Category : Antibiotics

Although there is strong evidence in mouse models of obesity that the gut microbiome can be manipulated to target obesity-related metabolic disorders, evidence in humans is scarce. Human studies examining the effects and underlying mechanisms of gut microbiota modulation on host metabolism are currently lacking. A recent randomized double-blind placebo-controlled trial, led by Dr. Ellen Blaak from the Department of…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although there is strong evidence in mouse models of obesity that the gut microbiome can be manipulated to target obesity-related metabolic disorders, evidence in humans is scarce. Human studies examining the effects and underlying mechanisms of gut microbiota modulation on host metabolism are currently lacking. A recent randomized double-blind placebo-controlled trial, led by Dr. Ellen Blaak from the Department of…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A recent study, led by Dr. Menghui Zhang from the State Key Laboratory of Microbial Metabolism at Shanghai Jiao Tong University (China), has shown that gut resistome of obese children is reduced after a dietary intervention.   The resistome refers to the collection of all the antibiotic resistant genes (ARGs) in a specific environment. The human gut microbiota includes a…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A recent study, led by Dr. Menghui Zhang from the State Key Laboratory of Microbial Metabolism at Shanghai Jiao Tong University (China), has shown that gut resistome of obese children is reduced after a dietary intervention.   The resistome refers to the collection of all the antibiotic resistant genes (ARGs) in a specific environment. The human gut microbiota includes a…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Inappropriate use of antibiotics promotes the emergence of multidrug-resistant pathogens, such as Vancomycin-resistant Enterococci (VRE), Methicillin-resistant Staphylococcus aureus (MRSA), and Multidrug-resistant (MDR) Enterobacteriaceae, which justifies the search for alternative clinical approaches. Indeed, increasing antibiotic resistance (AR) is partly an economic problem and is considered one of the most important threats to human health according to the World Health Organization. Noticeably,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Inappropriate use of antibiotics promotes the emergence of multidrug-resistant pathogens, such as Vancomycin-resistant Enterococci (VRE), Methicillin-resistant Staphylococcus aureus (MRSA), and Multidrug-resistant (MDR) Enterobacteriaceae, which justifies the search for alternative clinical approaches. Indeed, increasing antibiotic resistance (AR) is partly an economic problem and is considered one of the most important threats to human health according to the World Health Organization. Noticeably,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

For Dr. Vanni Bucci, assistant professor of computational biology at the University of Massachusetts Dartmouth, new treatments are not the only way to make progress in medicine. He believes doctors can greatly improve care by making better use of treatments that already exist -- even common ones like antibiotics. Bucci, a chemical/environmental engineer by training, builds mathematical models to describe…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

For Dr. Vanni Bucci, assistant professor of computational biology at the University of Massachusetts Dartmouth, new treatments are not the only way to make progress in medicine. He believes doctors can greatly improve care by making better use of treatments that already exist -- even common ones like antibiotics. Bucci, a chemical/environmental engineer by training, builds mathematical models to describe…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

After intestinal anastomosis -- resection and reconnection of intestinal segments -- the intestine sometimes fails to heal. Leakage, peritonitis, and sepsis can result: in other words, anastomotic leak. The underlying cause of this complication is unknown, but evidence is growing that intestinal microbes play a role. Authors of this paper showed the commensal bacterium Enterococcus faecalis contributes to the development…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

After intestinal anastomosis -- resection and reconnection of intestinal segments -- the intestine sometimes fails to heal. Leakage, peritonitis, and sepsis can result: in other words, anastomotic leak. The underlying cause of this complication is unknown, but evidence is growing that intestinal microbes play a role. Authors of this paper showed the commensal bacterium Enterococcus faecalis contributes to the development…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

An article published in Science Advances studied the microbiome of Yanomami subjects in the Amazon with no previous record of contact with non-Yanomami - the most isolated community ever explored in the microbiome literature. Researchers sampled the oral cavity, forearm skin, and feces from 34 Yanomami villagers. Overall, they found that the microbiome had the highest diversity ever reported in…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

An article published in Science Advances studied the microbiome of Yanomami subjects in the Amazon with no previous record of contact with non-Yanomami - the most isolated community ever explored in the microbiome literature. Researchers sampled the oral cavity, forearm skin, and feces from 34 Yanomami villagers. Overall, they found that the microbiome had the highest diversity ever reported in…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Stein and colleagues describe in their study, published in PLOS computational biology, how time series can help to study dynamics of the microbiota. Moreover, unlike usual cross sectional studies which lack a mechanistic understanding of the ecosystem's structure and its response to external perturbations, modelling dynamics can help to predict and recover the microbiota temporal dynamics. For example, they modeled…

GMFH Editing Team
GMFH Editing Team

Stein and colleagues describe in their study, published in PLOS computational biology, how time series can help to study dynamics of the microbiota. Moreover, unlike usual cross sectional studies which lack a mechanistic understanding of the ecosystem's structure and its response to external perturbations, modelling dynamics can help to predict and recover the microbiota temporal dynamics. For example, they modeled…

GMFH Editing Team
GMFH Editing Team

A Nature Medicine paper by Hitesh S Deshmukh and colleagues from the Division of Neonatology, Childrens Hospital of Philadelphia, Pennsilvania, USA reports an important aspect to the use of antibiotics in the integrity of the immune system in the newborn. Neonatal colonization by microbes, which begins immediately after birth, is influenced by gestational age and the mother’s microbiota and is…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

A Nature Medicine paper by Hitesh S Deshmukh and colleagues from the Division of Neonatology, Childrens Hospital of Philadelphia, Pennsilvania, USA reports an important aspect to the use of antibiotics in the integrity of the immune system in the newborn. Neonatal colonization by microbes, which begins immediately after birth, is influenced by gestational age and the mother’s microbiota and is…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.