Category : Immune Health

Over the past decade of studying the gut microbiome, we have learned that environmental factors related to diet and drugs are major determinants of gut microbiota composition and that their effects outweigh the influence of genetics. The GMFH publishing team is pleased to share a new summary document on the latest evidence regarding the influencing role of diet and probiotics…

GMFH Editing Team
GMFH Editing Team

Over the past decade of studying the gut microbiome, we have learned that environmental factors related to diet and drugs are major determinants of gut microbiota composition and that their effects outweigh the influence of genetics. The GMFH publishing team is pleased to share a new summary document on the latest evidence regarding the influencing role of diet and probiotics…

GMFH Editing Team
GMFH Editing Team

Gut Microbiota for Health is pleased to present its “Year at a Glance 2018” document! This new report is led by an editorial from Prof. Stéphane Schneider, Head of the Nutritional Support Unit in the Gastroenterology and Nutrition Department at Archet University Hospital in Nice (France), and summarizes the relevant advances in gut microbiota science in 2018. The last year…

GMFH Editing Team
GMFH Editing Team

Gut Microbiota for Health is pleased to present its “Year at a Glance 2018” document! This new report is led by an editorial from Prof. Stéphane Schneider, Head of the Nutritional Support Unit in the Gastroenterology and Nutrition Department at Archet University Hospital in Nice (France), and summarizes the relevant advances in gut microbiota science in 2018. The last year…

GMFH Editing Team
GMFH Editing Team

Hypotheses regarding the current rise in food allergies in Westernized countries tend to focus on the effect of an altered gut microbiome due to lifestyle changes. Among them, Westernized dietary patterns (but also antibiotic misuse and higher rates of Caesarean birth), have been the most closely studied factors in terms of their possible adverse effect on the gut microbiome, especially…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Hypotheses regarding the current rise in food allergies in Westernized countries tend to focus on the effect of an altered gut microbiome due to lifestyle changes. Among them, Westernized dietary patterns (but also antibiotic misuse and higher rates of Caesarean birth), have been the most closely studied factors in terms of their possible adverse effect on the gut microbiome, especially…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

This article has been coauthored by Marina Pérez-Gordo, Cristobalina Mayorga and Mariona Pascal. Allergic diseases include heterogenous inflammatory pathologies such as respiratory, cutaneous and food allergies. They are characterized by an immunological response with T lymphocytes as the main effector T cells, which promote the induction of other effector cells involved in allergic inflammation, such as mast cells, basophils, and…

Marina Pérez-Gordo
Basic Medical Science Department, Faculty of Medicine, CEU San Pablo University, ARADyAL, Madrid, Spain. Institute of Applied and Molecular Medicine (IMMA), Faculty of Medicine, CEU San Pablo University, Madrid, Spain.

This article has been coauthored by Marina Pérez-Gordo, Cristobalina Mayorga and Mariona Pascal. Allergic diseases include heterogenous inflammatory pathologies such as respiratory, cutaneous and food allergies. They are characterized by an immunological response with T lymphocytes as the main effector T cells, which promote the induction of other effector cells involved in allergic inflammation, such as mast cells, basophils, and…

Marina Pérez-Gordo
Basic Medical Science Department, Faculty of Medicine, CEU San Pablo University, ARADyAL, Madrid, Spain. Institute of Applied and Molecular Medicine (IMMA), Faculty of Medicine, CEU San Pablo University, Madrid, Spain.

Although the human gut microbiome is a source of antibiotic resistance genes (ARGs), until now, the intestinal resistome has not been extensively characterized. Challenges therefore remain, and they include figuring out the gut microbiota's contribution to the total pool of known ARGs and identifying ARGs in metagenomic data, given that they show distant homologies with known genes in databases. Researchers…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although the human gut microbiome is a source of antibiotic resistance genes (ARGs), until now, the intestinal resistome has not been extensively characterized. Challenges therefore remain, and they include figuring out the gut microbiota's contribution to the total pool of known ARGs and identifying ARGs in metagenomic data, given that they show distant homologies with known genes in databases. Researchers…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The intestinal epithelial barrier is not just a static physical barrier but rather interacts continuously with the gut microbiome and immune cells. An intact intestinal barrier protects the host against invasion of microorganisms and toxins whereas at the same time it allows absorption of essential fluids and nutrients. The pathophysiology of cirrhosis is associated with a dysfunctional intestinal barrier, which…

Oriol Juanola & Rubén Francés
Oriol Juanola is a PhD. student of the Hepatic and Intestinal Immunobiology Group at Miguel Hernández University (Alicante, Spain). The group is interested in molecular and cellular aspects around the immune system that are responsible for the surveillance, response and regulation of homeostasis with our gut microbiota in the so-called "gut-liver axis", a central element in different metabolic pathologies within the scope of the gastroenterology and hepatology. The translation of these aspects, addressed from different methodological perspectives, to the clinical field is also relevant for the Group in order to improve the diagnosis, treatment and/or prognosis of these diseases. Rubén Francés is professor of Immunology and Head of the Hepatic and Intestinal Immunobiology Group at Miguel Hernández University and the Biomedical Research Networking Center in Hepatic and Digestive Diseases (CIBEREHD).

The intestinal epithelial barrier is not just a static physical barrier but rather interacts continuously with the gut microbiome and immune cells. An intact intestinal barrier protects the host against invasion of microorganisms and toxins whereas at the same time it allows absorption of essential fluids and nutrients. The pathophysiology of cirrhosis is associated with a dysfunctional intestinal barrier, which…

Oriol Juanola & Rubén Francés
Oriol Juanola is a PhD. student of the Hepatic and Intestinal Immunobiology Group at Miguel Hernández University (Alicante, Spain). The group is interested in molecular and cellular aspects around the immune system that are responsible for the surveillance, response and regulation of homeostasis with our gut microbiota in the so-called "gut-liver axis", a central element in different metabolic pathologies within the scope of the gastroenterology and hepatology. The translation of these aspects, addressed from different methodological perspectives, to the clinical field is also relevant for the Group in order to improve the diagnosis, treatment and/or prognosis of these diseases. Rubén Francés is professor of Immunology and Head of the Hepatic and Intestinal Immunobiology Group at Miguel Hernández University and the Biomedical Research Networking Center in Hepatic and Digestive Diseases (CIBEREHD).

Studies exploring the neonatal microbiome during early life have been performed mainly in the hospital setting, with both mode of delivery and antibiotics having the most profound impact on the microbiome. However, the development of the neonatal microbiome in the absence of routine hospital interventions during delivery has not yet been studied. A new study, led by Prof. Maria Gloria…

GMFH Editing Team
GMFH Editing Team

Studies exploring the neonatal microbiome during early life have been performed mainly in the hospital setting, with both mode of delivery and antibiotics having the most profound impact on the microbiome. However, the development of the neonatal microbiome in the absence of routine hospital interventions during delivery has not yet been studied. A new study, led by Prof. Maria Gloria…

GMFH Editing Team
GMFH Editing Team

The use of antibiotics has long been related to a perturbation of the composition and functions of commensal bacterial communities. Some bacteria die in response to antibiotics while gut microbes that harbor antibiotic resistance genes survive. However, little is known regarding the impact of antibiotics on the eradication and recovery of gut microorganisms. A new study, led by Prof. Oluf…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The use of antibiotics has long been related to a perturbation of the composition and functions of commensal bacterial communities. Some bacteria die in response to antibiotics while gut microbes that harbor antibiotic resistance genes survive. However, little is known regarding the impact of antibiotics on the eradication and recovery of gut microorganisms. A new study, led by Prof. Oluf…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Western diets high in fats and sugars, modern lifestyles with stress and sedentarism and the indiscriminate use of antibiotics together with other frequently prescribed drugs -such as non-steroidal anti-inflammatory drugs and proton pump inhibitors- are major drivers of changes in microbiota composition and gut barrier disruption. (Dr. Maria Rescigno) The GMFH publishing team is pleased to share a new summary…

GMFH Editing Team
GMFH Editing Team

Western diets high in fats and sugars, modern lifestyles with stress and sedentarism and the indiscriminate use of antibiotics together with other frequently prescribed drugs -such as non-steroidal anti-inflammatory drugs and proton pump inhibitors- are major drivers of changes in microbiota composition and gut barrier disruption. (Dr. Maria Rescigno) The GMFH publishing team is pleased to share a new summary…

GMFH Editing Team
GMFH Editing Team