Category : Gut Microbiota

Maternal physiology and metabolism during pregnancy adjust so the fetus may grow healthy. As part of these changes, the gut microbiota evolves towards a pro-inflammatory profile, which contributes to a healthy pregnancy. Even so, the extent to which gut microbiota alterations induced by pregnancy and lactation may change autoimmune mechanisms that are involved in disease has not yet been explored.…

GMFH Editing Team
GMFH Editing Team

Maternal physiology and metabolism during pregnancy adjust so the fetus may grow healthy. As part of these changes, the gut microbiota evolves towards a pro-inflammatory profile, which contributes to a healthy pregnancy. Even so, the extent to which gut microbiota alterations induced by pregnancy and lactation may change autoimmune mechanisms that are involved in disease has not yet been explored.…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

The microorganisms inhabiting the human gut can alter the chemical structures of drugs, leading to changes in their bioavailability, toxicity and efficacy. Although the gut microbial enzymes responsible for these chemical modifications are poorly understood, microbial mediation of therapeutic effects has been reported for metformin, chemotherapeutic drugs and antidepressants. A gut microbial enzymatic pathway is involved in metabolizing the drug…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The microorganisms inhabiting the human gut can alter the chemical structures of drugs, leading to changes in their bioavailability, toxicity and efficacy. Although the gut microbial enzymes responsible for these chemical modifications are poorly understood, microbial mediation of therapeutic effects has been reported for metformin, chemotherapeutic drugs and antidepressants. A gut microbial enzymatic pathway is involved in metabolizing the drug…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Preterm infants are at a high risk of growth failure that may affect their long-term health outcomes. Different factors have been involved in the etiology of postnatal growth failure in preterm infants, but despite research efforts regarding clinical management, growth failure rates continue to increase. Although differences in gut microbiota composition have been found in preterm infants compared with full-term…

GMFH Editing Team
GMFH Editing Team

Preterm infants are at a high risk of growth failure that may affect their long-term health outcomes. Different factors have been involved in the etiology of postnatal growth failure in preterm infants, but despite research efforts regarding clinical management, growth failure rates continue to increase. Although differences in gut microbiota composition have been found in preterm infants compared with full-term…

GMFH Editing Team
GMFH Editing Team

The modification of the human gut microbiota’s composition and function is one of the plausible mechanisms that has just recently started being explored in relation to how exercise affects health. Although gut microbiome composition tends to show higher variability under environmental pressures, its diversity functionality tends to remain consistent within and across subjects. In professional athletes, however, little is known…

GMFH Editing Team
GMFH Editing Team

The modification of the human gut microbiota’s composition and function is one of the plausible mechanisms that has just recently started being explored in relation to how exercise affects health. Although gut microbiome composition tends to show higher variability under environmental pressures, its diversity functionality tends to remain consistent within and across subjects. In professional athletes, however, little is known…

GMFH Editing Team
GMFH Editing Team

The enteric nervous system (ENS)—also called “our second brain”—is an autonomous part of the nervous system consisting of in the myenteric and submucosal plexus within the wall of the gastrointestinal tract. Comprising primary afferent neurons, interneurons and motor neurons, alongside intestinal cells involved in immune responses and endocrine and paracrine functions, it is involved in the sensory-motor control of the…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The enteric nervous system (ENS)—also called “our second brain”—is an autonomous part of the nervous system consisting of in the myenteric and submucosal plexus within the wall of the gastrointestinal tract. Comprising primary afferent neurons, interneurons and motor neurons, alongside intestinal cells involved in immune responses and endocrine and paracrine functions, it is involved in the sensory-motor control of the…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

A current challenge in gut microbiome science is that of characterizing the effects of food groups on gut microbial communities instead of focusing on isolated nutrients. Although prebiotics provide health benefits by specifically altering the composition or activity of the gut microbiota, not all dietary fibers are prebiotics and they can benefit gut bacterial groups in different ways. A new…

GMFH Editing Team
GMFH Editing Team

A current challenge in gut microbiome science is that of characterizing the effects of food groups on gut microbial communities instead of focusing on isolated nutrients. Although prebiotics provide health benefits by specifically altering the composition or activity of the gut microbiota, not all dietary fibers are prebiotics and they can benefit gut bacterial groups in different ways. A new…

GMFH Editing Team
GMFH Editing Team

The gut microbiome is made up of different taxonomic groups that include bacteria, archaea, microbial eukaryotes (fungi and protozoa) and viruses. Bacteriophages or phages are prokaryotic viruses that represent a substantial fraction of the microorganisms residing in the gut, although their interactions with gut bacteria have remained largely underexplored due to the challenge of characterizing phages encountered in previous research.…

GMFH Editing Team
GMFH Editing Team

The gut microbiome is made up of different taxonomic groups that include bacteria, archaea, microbial eukaryotes (fungi and protozoa) and viruses. Bacteriophages or phages are prokaryotic viruses that represent a substantial fraction of the microorganisms residing in the gut, although their interactions with gut bacteria have remained largely underexplored due to the challenge of characterizing phages encountered in previous research.…

GMFH Editing Team
GMFH Editing Team

Specific dietary modifications have been an area of focus to treat a myriad of diseases such as obesity and IBS. However, the individual response to dietary interventions can vary greatly, partly due to our unique gut microbiota compositions. Personalized nutrition is a promising area of research that aims to predict physiological response to dietary interventions based on a person's gut microbial…

Allison Clark
Allison Clark has a master in nutrition and health from Open University in Barcelona and a master in journalism. She is a freelance writer and nutritionist and has written various peer review papers about the role the gut microbiota plays in health, disease and endurance exercise performance. Allison is passionate about the role diet and the gut microbiota play in health and disease. Follow her on Twitter @Heal_your_Gut

Specific dietary modifications have been an area of focus to treat a myriad of diseases such as obesity and IBS. However, the individual response to dietary interventions can vary greatly, partly due to our unique gut microbiota compositions. Personalized nutrition is a promising area of research that aims to predict physiological response to dietary interventions based on a person's gut microbial…

Allison Clark
Allison Clark has a master in nutrition and health from Open University in Barcelona and a master in journalism. She is a freelance writer and nutritionist and has written various peer review papers about the role the gut microbiota plays in health, disease and endurance exercise performance. Allison is passionate about the role diet and the gut microbiota play in health and disease. Follow her on Twitter @Heal_your_Gut

Recurrence of inflammatory lesions is frequent in patients undergoing ileal resection for Crohn’s disease (CD). Although male gender, active smoking at surgery and previous intestinal resection have all been associated with a higher risk of endoscopic post-operative recurrence—as assessed by ileocolonoscopy—there is not a single clinical risk factor that can be used as a perfect predictor of early postoperative endoscopic…

GMFH Editing Team
GMFH Editing Team

Recurrence of inflammatory lesions is frequent in patients undergoing ileal resection for Crohn’s disease (CD). Although male gender, active smoking at surgery and previous intestinal resection have all been associated with a higher risk of endoscopic post-operative recurrence—as assessed by ileocolonoscopy—there is not a single clinical risk factor that can be used as a perfect predictor of early postoperative endoscopic…

GMFH Editing Team
GMFH Editing Team