Category : Gut Microbiota Composition

Host genetics may impact the gut microbiome, as supported by twin studies revealing associations between specific alleles in the host and members or functions of the gut microbiome. However, it is unknown whether the gut microbiota could respond to copy-number variation in host genes, which are considered to be a source of genetic variation. A new study, led by Dr.…

GMFH Editing Team
GMFH Editing Team

Host genetics may impact the gut microbiome, as supported by twin studies revealing associations between specific alleles in the host and members or functions of the gut microbiome. However, it is unknown whether the gut microbiota could respond to copy-number variation in host genes, which are considered to be a source of genetic variation. A new study, led by Dr.…

GMFH Editing Team
GMFH Editing Team

The human milk microbiota is an important source of commensal microorganisms for the infant gut. Although both maternal and infant microbiomes are shaped by a multitude of factors, including delivery mode, geographic location and the method of breastfeeding, the extent to which bacterial taxa in a mother’s breast milk correlates with an infant’s fecal microbiota across different geographic locations is unclear.…

GMFH Editing Team
GMFH Editing Team

The human milk microbiota is an important source of commensal microorganisms for the infant gut. Although both maternal and infant microbiomes are shaped by a multitude of factors, including delivery mode, geographic location and the method of breastfeeding, the extent to which bacterial taxa in a mother’s breast milk correlates with an infant’s fecal microbiota across different geographic locations is unclear.…

GMFH Editing Team
GMFH Editing Team

Although twin research has shown that gut microbiota features a heritable component, we do not know whether gut microbial genetic variations can shape phenotypic differences that affect host health. A new study, led by Dr. Eran Segal from the Weizmann Institute of Science in Rehovot (Israel), has identified structural variations in gut microbial genomes that vary across people and are…

GMFH Editing Team
GMFH Editing Team

Although twin research has shown that gut microbiota features a heritable component, we do not know whether gut microbial genetic variations can shape phenotypic differences that affect host health. A new study, led by Dr. Eran Segal from the Weizmann Institute of Science in Rehovot (Israel), has identified structural variations in gut microbial genomes that vary across people and are…

GMFH Editing Team
GMFH Editing Team

Genes alone cannot explain the current rise in colorectal cancer (CRC) and scientists are now trying to elucidate the gut microbiota's contribution as an important player. Previous human research has shown mechanisms by which the bacteria might affect tumorigenesis, especially in the early stages. However, gut microbiome signatures of CRC in association studies have not always been validated across different…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Genes alone cannot explain the current rise in colorectal cancer (CRC) and scientists are now trying to elucidate the gut microbiota's contribution as an important player. Previous human research has shown mechanisms by which the bacteria might affect tumorigenesis, especially in the early stages. However, gut microbiome signatures of CRC in association studies have not always been validated across different…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Bariatric surgery (BS) appears as a solution for managing cardiovascular risk in people with a severe and morbid Body Mass Index (BMI > 35-40 kg/m2). Although previous research has shown that the gut microbiota profile in obesity is characterized by low microbial gene richness and is correlated with some metabolic and inflammatory markers, little is known about its contribution to…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Bariatric surgery (BS) appears as a solution for managing cardiovascular risk in people with a severe and morbid Body Mass Index (BMI > 35-40 kg/m2). Although previous research has shown that the gut microbiota profile in obesity is characterized by low microbial gene richness and is correlated with some metabolic and inflammatory markers, little is known about its contribution to…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The increase in cardiovascular diseases (CVD) that comes with age has been related to an arterial dysfunction linked to higher inflammatory and oxidative stress responses. Although there is suggestion that a perturbed gut microbiome plays a role in the aging phenotype and the onset of physical frailty, the mechanisms that link changes in gut microbiome composition and an increased risk…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The increase in cardiovascular diseases (CVD) that comes with age has been related to an arterial dysfunction linked to higher inflammatory and oxidative stress responses. Although there is suggestion that a perturbed gut microbiome plays a role in the aging phenotype and the onset of physical frailty, the mechanisms that link changes in gut microbiome composition and an increased risk…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Probiotics have different potential therapeutic uses, although their mechanisms of action and how they might change after administration are not fully studied. In contrast to traditional drugs, probiotics can evolve during treatment, but how this process works inside the gut remains largely elusive. A new study, led by Dr. Gautam Dantas from the Washington University School of Medicine in St.…

GMFH Editing Team
GMFH Editing Team

Probiotics have different potential therapeutic uses, although their mechanisms of action and how they might change after administration are not fully studied. In contrast to traditional drugs, probiotics can evolve during treatment, but how this process works inside the gut remains largely elusive. A new study, led by Dr. Gautam Dantas from the Washington University School of Medicine in St.…

GMFH Editing Team
GMFH Editing Team

Although the underlying mechanisms involved in inflammatory bowel disease (IBD) pathogenesis remain elusive, it is known that certain genes, which are shared by both Crohn’s disease (CD) and ulcerative colitis (UC) patients, may show a predisposition to the development of this disease. Furthermore, the intestinal bacterial and fungal microbiota might also drive disease pathogenesis and progression. Despite this knowledge, the…

GMFH Editing Team
GMFH Editing Team

Although the underlying mechanisms involved in inflammatory bowel disease (IBD) pathogenesis remain elusive, it is known that certain genes, which are shared by both Crohn’s disease (CD) and ulcerative colitis (UC) patients, may show a predisposition to the development of this disease. Furthermore, the intestinal bacterial and fungal microbiota might also drive disease pathogenesis and progression. Despite this knowledge, the…

GMFH Editing Team
GMFH Editing Team

Celiac disease is a common food sensitivity triggered by gluten and its incidence is rising at an alarming rate. The reasons for this are not fully understood but suggestions are that they relate to changes in gut microbial composition or function. As part of previous research into gluten digestion processes, Dr. Alberto Caminero of  McMaster University (Canada) had described a…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Celiac disease is a common food sensitivity triggered by gluten and its incidence is rising at an alarming rate. The reasons for this are not fully understood but suggestions are that they relate to changes in gut microbial composition or function. As part of previous research into gluten digestion processes, Dr. Alberto Caminero of  McMaster University (Canada) had described a…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Fermented foods have been produced and consumed since the beginning of human civilization and are now, once again, becoming more prevalent in our diets and in a variety of forms. Prof. Robert Hutkins from the University of Nebraska (USA) studies the role of beneficial microbes in manufacturing fermented foods and in human health. In January 2019, he published the second…

GMFH Editing Team
GMFH Editing Team

Fermented foods have been produced and consumed since the beginning of human civilization and are now, once again, becoming more prevalent in our diets and in a variety of forms. Prof. Robert Hutkins from the University of Nebraska (USA) studies the role of beneficial microbes in manufacturing fermented foods and in human health. In January 2019, he published the second…

GMFH Editing Team
GMFH Editing Team