Category : Dysbiosis

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating illness of unknown underlying mechanisms and without an accepted therapy. According to Fukuda diagnostic criteria, primary symptoms reported by patients are fatigue, muscle and/or joint paint, sore throat, headaches, unrefreshing sleep, and post-exertional malaise. Individuals diagnosed with ME/CFS often report gastrointestinal symptoms such as constipation, diarrhoea, and intestinal discomfort that are part…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating illness of unknown underlying mechanisms and without an accepted therapy. According to Fukuda diagnostic criteria, primary symptoms reported by patients are fatigue, muscle and/or joint paint, sore throat, headaches, unrefreshing sleep, and post-exertional malaise. Individuals diagnosed with ME/CFS often report gastrointestinal symptoms such as constipation, diarrhoea, and intestinal discomfort that are part…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Beyond affecting host metabolism, the gut microbiota may be able to shape brain function and behaviour through the microbiota-gut-brain axis. A recent study, led by Dr. John Penders, from the Department of Medical Microbiology at Maastricht University Medical Centre (The Netherlands), has found that gut dysbiosis and gastrointestinal complaints in anorexia nervosa patients do not recover after weight gain and/or…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Beyond affecting host metabolism, the gut microbiota may be able to shape brain function and behaviour through the microbiota-gut-brain axis. A recent study, led by Dr. John Penders, from the Department of Medical Microbiology at Maastricht University Medical Centre (The Netherlands), has found that gut dysbiosis and gastrointestinal complaints in anorexia nervosa patients do not recover after weight gain and/or…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

A recent study, led by Dr. Peng Xie from the Chongqing Medical University in China, has demonstrated that intestinal ‘dysbiosis’ may have a causal role in the development of depressive-like behaviours in mice through altering host metabolism.   It has been previously described that the gut microbiota may be an environmental factor that can modulate brain physiology through the microbiota-gut-brain…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

A recent study, led by Dr. Peng Xie from the Chongqing Medical University in China, has demonstrated that intestinal ‘dysbiosis’ may have a causal role in the development of depressive-like behaviours in mice through altering host metabolism.   It has been previously described that the gut microbiota may be an environmental factor that can modulate brain physiology through the microbiota-gut-brain…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

It has been previously reported that systemic lupus erythematosus (SLE) patients show intestinal ‘dysbiosis’, characterized by a reduced Firmicutes/Bacteroidetes ratio. The overall bacterial load and diversity is similar between those with SLE and controls.   A new study, led by Dr. Ana Suárez from the Department of Functional Biology at Faculty of Medicine in the University of Oviedo (Asturias, Spain),…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

It has been previously reported that systemic lupus erythematosus (SLE) patients show intestinal ‘dysbiosis’, characterized by a reduced Firmicutes/Bacteroidetes ratio. The overall bacterial load and diversity is similar between those with SLE and controls.   A new study, led by Dr. Ana Suárez from the Department of Functional Biology at Faculty of Medicine in the University of Oviedo (Asturias, Spain),…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A new study, led by Dr. Susanne Wolf from the Department of Cellular Neuroscience at Max-Delbrueck-Centre for Molecular Medicine in Berlin (Germany), has found that prolonged antibiotic treatment, which kills gut bacteria, can also stop growth of new brain cells in mice. Although it has been previously reported that antibiotic-induced gut dysbiosis may lead to impaired cognition in mice, little…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A new study, led by Dr. Susanne Wolf from the Department of Cellular Neuroscience at Max-Delbrueck-Centre for Molecular Medicine in Berlin (Germany), has found that prolonged antibiotic treatment, which kills gut bacteria, can also stop growth of new brain cells in mice. Although it has been previously reported that antibiotic-induced gut dysbiosis may lead to impaired cognition in mice, little…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Mechanisms involved in gut microbiota-brain communication are largely unknown and a better understanding of these complex relationships might provide new targeted therapies. A recent study, led by Prof. Peter Holzer from the Research Unit of Translational Neurogastroenterology at Medical University of Graz in Austria, has found that intragastric treatment of mice with an antibiotic mixture impaired novel object recognition. This…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Mechanisms involved in gut microbiota-brain communication are largely unknown and a better understanding of these complex relationships might provide new targeted therapies. A recent study, led by Prof. Peter Holzer from the Research Unit of Translational Neurogastroenterology at Medical University of Graz in Austria, has found that intragastric treatment of mice with an antibiotic mixture impaired novel object recognition. This…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A new study, led by Professor Heinrich Jasper from the Buck Institute for Research on Aging in Novato (USA), has found that inhibiting age-related inflammation maintains a healthy gut microbiota and extends lifespan in flies.   Aging in flies and humans is associated with chronic inflammation, several tissue dysfunctions such as metaplasias, and ‘dysbiosis’ of the commensal microbiota. Research at…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A new study, led by Professor Heinrich Jasper from the Buck Institute for Research on Aging in Novato (USA), has found that inhibiting age-related inflammation maintains a healthy gut microbiota and extends lifespan in flies.   Aging in flies and humans is associated with chronic inflammation, several tissue dysfunctions such as metaplasias, and ‘dysbiosis’ of the commensal microbiota. Research at…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A recent study, led by Dr Heping Zhang from the Key Laboratory of Dairy Biotechnology and Bioengineering in China, has reported that early detection of gout may be possible through a diagnosis model that uses gout-associated bacteria.   Gout is an auto-inflammatory disease that has been rising worldwide. It is characterized by increased accumulation and reduced excretion of uric acid,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A recent study, led by Dr Heping Zhang from the Key Laboratory of Dairy Biotechnology and Bioengineering in China, has reported that early detection of gout may be possible through a diagnosis model that uses gout-associated bacteria.   Gout is an auto-inflammatory disease that has been rising worldwide. It is characterized by increased accumulation and reduced excretion of uric acid,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Rheumatoid arthritis (RA) is a debilitating immune disorder of unknown cause. Recent studies have raised the possibility that changes in the mucosal microbiome could be involved in disease onset and progression. Zhang and colleagues conducted a case-control metagenome-wide association study (MGWAS) of the fecal, dental, and salivary microbiome in patients with RA. The microbiome at all three sites deviated from…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Rheumatoid arthritis (RA) is a debilitating immune disorder of unknown cause. Recent studies have raised the possibility that changes in the mucosal microbiome could be involved in disease onset and progression. Zhang and colleagues conducted a case-control metagenome-wide association study (MGWAS) of the fecal, dental, and salivary microbiome in patients with RA. The microbiome at all three sites deviated from…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

A study by De Palma, et al. used germ-free and specific pathogen-free mouse models to investigate the effects of early-life stress. Researchers reported that stress (maternal separation) altered the hypothalamic-pituitary-adrenal axis in mice. Colonizing adult germ-free mice with the same microbiota led to distinct microbial profiles in mice who had experienced early-life stress. After colonization, behaviour was altered in the stressed…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

A study by De Palma, et al. used germ-free and specific pathogen-free mouse models to investigate the effects of early-life stress. Researchers reported that stress (maternal separation) altered the hypothalamic-pituitary-adrenal axis in mice. Colonizing adult germ-free mice with the same microbiota led to distinct microbial profiles in mice who had experienced early-life stress. After colonization, behaviour was altered in the stressed…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.