Category : Dysbiosis

Previous research has shown that gut microbiota dysbiosis may be involved in the pathogenesis of ankylosing spondylitis (AS), which is a chronic inflammatory disease that mainly affects the sacroiliac joints and spine. However, the implications it could have for both local and systemic immune responses in AS has not yet been explored. A recent study, led by Dr. Giovanni Triolo…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that gut microbiota dysbiosis may be involved in the pathogenesis of ankylosing spondylitis (AS), which is a chronic inflammatory disease that mainly affects the sacroiliac joints and spine. However, the implications it could have for both local and systemic immune responses in AS has not yet been explored. A recent study, led by Dr. Giovanni Triolo…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Gut microbiota dysbiosis, which has been defined as “the altered proportion and activity of bacterial groups of gut microbiota”, is suspected to be involved in several metabolic diseases such as hepatic steatosis, type 2 diabetes, and obesity. However, the underlying mechanisms are still a matter of debate. In a recent study, led by Dr. Matteo Serino from the Institut Nacional…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Gut microbiota dysbiosis, which has been defined as “the altered proportion and activity of bacterial groups of gut microbiota”, is suspected to be involved in several metabolic diseases such as hepatic steatosis, type 2 diabetes, and obesity. However, the underlying mechanisms are still a matter of debate. In a recent study, led by Dr. Matteo Serino from the Institut Nacional…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Celiac disease (CeD) is a complex immune mediated disorder that is triggered by abnormal immune responses to the dietary protein gluten, which is found in grains like wheat, barley, and rye. Normally, immune tolerance to dietary proteins prevents inflammatory immune responses from developing. However, in those with CeD, the presence of HLA susceptibility genes plus unknown environmental or immune triggers…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Celiac disease (CeD) is a complex immune mediated disorder that is triggered by abnormal immune responses to the dietary protein gluten, which is found in grains like wheat, barley, and rye. Normally, immune tolerance to dietary proteins prevents inflammatory immune responses from developing. However, in those with CeD, the presence of HLA susceptibility genes plus unknown environmental or immune triggers…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

A recent study led by Dr. Jun Sun (Department of Medicine, University of Illinois, Chicago, USA) has found that butyrate, a bacterial metabolic by-product, may normalize the intestinal environment, including gut microbiota composition, and increase life span in a mouse model of amyotrophic lateral sclerosis (ALS). In humans, ALS (also known as Lou Gehrig’s disease) is a neurodegenerative disease in…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A recent study led by Dr. Jun Sun (Department of Medicine, University of Illinois, Chicago, USA) has found that butyrate, a bacterial metabolic by-product, may normalize the intestinal environment, including gut microbiota composition, and increase life span in a mouse model of amyotrophic lateral sclerosis (ALS). In humans, ALS (also known as Lou Gehrig’s disease) is a neurodegenerative disease in…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the gut microbiota may have a role in the pathogenesis of immune-related diseases involving chronic inflammation, such as rheumatoid arthritis, Crohn’s disease, multiple sclerosis, and others. A recent review, led by Dr. Hai Lu from the Department of Orthopedic Surgery at The Third Affiliated Hospital of Southern Medical University in Guangzhou (China), discusses the existing…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the gut microbiota may have a role in the pathogenesis of immune-related diseases involving chronic inflammation, such as rheumatoid arthritis, Crohn’s disease, multiple sclerosis, and others. A recent review, led by Dr. Hai Lu from the Department of Orthopedic Surgery at The Third Affiliated Hospital of Southern Medical University in Guangzhou (China), discusses the existing…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Individuals with cirrhosis have been reported to show a duodenal bacterial dysbiosis that might be related to the composition of the oral microbiota. Although the relationship between cirrhosis and gut microbiota is only observational and causality cannot be inferred yet, studying the effects of probiotics in patients with cirrhosis is promising. A recent study, led by Vanessa Stadlbauer from the…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Individuals with cirrhosis have been reported to show a duodenal bacterial dysbiosis that might be related to the composition of the oral microbiota. Although the relationship between cirrhosis and gut microbiota is only observational and causality cannot be inferred yet, studying the effects of probiotics in patients with cirrhosis is promising. A recent study, led by Vanessa Stadlbauer from the…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Recent studies have pointed out the role a dysbiosis in gut microbiota plays in the onset and progression of liver disease. Chronic alcohol consumption is known to be a major disruptor of the microbial community harboured in the intestines and can both cause bacterial alteration, increasing the proportion of harmful bacteria and reducing levels of beneficial bacteria; and also it…

GMFH Editing Team
GMFH Editing Team

Recent studies have pointed out the role a dysbiosis in gut microbiota plays in the onset and progression of liver disease. Chronic alcohol consumption is known to be a major disruptor of the microbial community harboured in the intestines and can both cause bacterial alteration, increasing the proportion of harmful bacteria and reducing levels of beneficial bacteria; and also it…

GMFH Editing Team
GMFH Editing Team

A mounting body of scientific evidence suggests a link between the gut microbiome and human metabolic health. Indeed, alteration of microbial composition and function in patients with type 2 diabetes (T2D) appears to be a key feature in the pathogenesis of the disease. However, whether the insulin resistance (IR)-associated serum metabolome may predict metabolic and cardiovascular disorders is unknown. A…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A mounting body of scientific evidence suggests a link between the gut microbiome and human metabolic health. Indeed, alteration of microbial composition and function in patients with type 2 diabetes (T2D) appears to be a key feature in the pathogenesis of the disease. However, whether the insulin resistance (IR)-associated serum metabolome may predict metabolic and cardiovascular disorders is unknown. A…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

It is already known that a reduction in gut microbial richness is the hallmark change of human immunodeficiency virus (HIV) infection, but how this dysbiosis is established in the HIV-exposed uninfected infant is poorly understood. A recent cross-sectional study, led by Dr. Grace M. Aldrovandi from the Children’s Hospital Los Angeles in Los Angeles (USA), suggests that perturbations in the…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

It is already known that a reduction in gut microbial richness is the hallmark change of human immunodeficiency virus (HIV) infection, but how this dysbiosis is established in the HIV-exposed uninfected infant is poorly understood. A recent cross-sectional study, led by Dr. Grace M. Aldrovandi from the Children’s Hospital Los Angeles in Los Angeles (USA), suggests that perturbations in the…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

It has been previously reported that the gut microbiota might influence cancer outcomes through its interaction with host immunity at different levels. Current scientific evidence indicates that the gut microbiota may play a role in the progression from normal to advanced adenoma, and subsequently to colorectal cancer (CRC). Controversial data exist regarding the gut microbiota composition associated with CRC or…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

It has been previously reported that the gut microbiota might influence cancer outcomes through its interaction with host immunity at different levels. Current scientific evidence indicates that the gut microbiota may play a role in the progression from normal to advanced adenoma, and subsequently to colorectal cancer (CRC). Controversial data exist regarding the gut microbiota composition associated with CRC or…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados