Category : Gut Microbiota Composition

The current antibiotic resistance epidemic is reaching levels higher than previously reported. And the roots of this epidemic can be found not only in an increase in outpatient antibiotic use, but also on the high proportions of resistant bacteria transmitted from food-producing animals. The effects of antibiotics on human gut bacterial diversity is of particular relevance during early life. It…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The current antibiotic resistance epidemic is reaching levels higher than previously reported. And the roots of this epidemic can be found not only in an increase in outpatient antibiotic use, but also on the high proportions of resistant bacteria transmitted from food-producing animals. The effects of antibiotics on human gut bacterial diversity is of particular relevance during early life. It…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Short-chain fatty acids (SCFAs) (such as acetate, propionate, butyrate) are byproducts of bacterial fermentation in the gut and are frequently reduced in people with diabetes, obesity, autoimmune disorders, and cancer. A growing body of research points to the role of SCFAs in governing the mechanism by which the gut microbiome affects host physiology - an exciting prospect considering the current…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

Short-chain fatty acids (SCFAs) (such as acetate, propionate, butyrate) are byproducts of bacterial fermentation in the gut and are frequently reduced in people with diabetes, obesity, autoimmune disorders, and cancer. A growing body of research points to the role of SCFAs in governing the mechanism by which the gut microbiome affects host physiology - an exciting prospect considering the current…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

Other than gut microbiota's well-known functions, which include nutrient metabolism and absorption, xenobiotic and drug metabolism, and immune development, its role in protecting against pathogens has been poorly characterized. Previous research has identified some microbiota-mediated colonization resistance mechanisms, while little is known about whether microbial metabolites may also limit pathogen colonization. A new study, led by Dr. Denise Monack from…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Other than gut microbiota's well-known functions, which include nutrient metabolism and absorption, xenobiotic and drug metabolism, and immune development, its role in protecting against pathogens has been poorly characterized. Previous research has identified some microbiota-mediated colonization resistance mechanisms, while little is known about whether microbial metabolites may also limit pathogen colonization. A new study, led by Dr. Denise Monack from…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Surf the web and you’ll find many claims about probiotics, but many times what’s said isn’t based on fact. Sometimes this is because the author just doesn’t know the science. Sometimes it seems to be intentional, to promote some aspect of one product as better than other products. The International Scientific Association for Probiotics and Prebiotics (ISAPP) created an infographic…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

Surf the web and you’ll find many claims about probiotics, but many times what’s said isn’t based on fact. Sometimes this is because the author just doesn’t know the science. Sometimes it seems to be intentional, to promote some aspect of one product as better than other products. The International Scientific Association for Probiotics and Prebiotics (ISAPP) created an infographic…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

While changes in the human gut microbiome's composition and function have been related to several diseases and types of medication, variability between studies limits the comparing of findings. Another factor that limits our understanding of how disease-medication interactions have an impact on gut microbiota is the fact that the gut microbiome has been studied in relation to single diseases without…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

While changes in the human gut microbiome's composition and function have been related to several diseases and types of medication, variability between studies limits the comparing of findings. Another factor that limits our understanding of how disease-medication interactions have an impact on gut microbiota is the fact that the gut microbiome has been studied in relation to single diseases without…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The fact that healthy relatives of patients with inflammatory bowel disease (IBD) have a higher risk of developing IBD and display mucosal microbiota dysbiosis indicates that both genetic background and alterations of the gut microbiome might trigger disease phenotype. A study, led by Prof. Kevin Whelan from the Faculty of Life Sciences & Medicine at King’s College London (United Kingdom),…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The fact that healthy relatives of patients with inflammatory bowel disease (IBD) have a higher risk of developing IBD and display mucosal microbiota dysbiosis indicates that both genetic background and alterations of the gut microbiome might trigger disease phenotype. A study, led by Prof. Kevin Whelan from the Faculty of Life Sciences & Medicine at King’s College London (United Kingdom),…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

According to many scientific studies, having a balanced gut microbiota is essential for gut health. Just like a big city, where the whole community works together to make the place work, our gut is populated by trillions of microbes that help us live a healthy life. “We have a lot of bacteria in our body and the reason they are…

GMFH Editing Team
GMFH Editing Team

According to many scientific studies, having a balanced gut microbiota is essential for gut health. Just like a big city, where the whole community works together to make the place work, our gut is populated by trillions of microbes that help us live a healthy life. “We have a lot of bacteria in our body and the reason they are…

GMFH Editing Team
GMFH Editing Team

Arterial stiffness—defined as the reduced capability of an artery to expand and contract in response to pressure changes—has been previously reported as an independent predictor of major adverse cardiovascular events in individuals with metabolic syndrome. However, it is poorly associated with traditional cardiovascular risk factors, including hyperlipidemia, diabetes mellitus, obesity and smoking. Furthermore, we do not know whether gut microbiome…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Arterial stiffness—defined as the reduced capability of an artery to expand and contract in response to pressure changes—has been previously reported as an independent predictor of major adverse cardiovascular events in individuals with metabolic syndrome. However, it is poorly associated with traditional cardiovascular risk factors, including hyperlipidemia, diabetes mellitus, obesity and smoking. Furthermore, we do not know whether gut microbiome…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

One of the strategies used by vertebrate hosts to defend against bacterial pathogens is that of sequestering transition metals required for intracellular and extracellular pathogen survival. This process is called “nutritional immunity” and, in response, bacteria have evolved strategies to access metals and counteract this host mechanism of defense. A new review, led by Dr. Christopher Lopez and Prof. Eric…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

One of the strategies used by vertebrate hosts to defend against bacterial pathogens is that of sequestering transition metals required for intracellular and extracellular pathogen survival. This process is called “nutritional immunity” and, in response, bacteria have evolved strategies to access metals and counteract this host mechanism of defense. A new review, led by Dr. Christopher Lopez and Prof. Eric…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous experimental research has found that metabolomics can be used to monitor the impact of host diet on gut microbiota functionality. These data suggest that focusing on gut microbiota functionality may allow for a better characterization of the gut microbiota and its interaction with the host than only studying its composition. A new study, led by Dr. Tim Spector and…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous experimental research has found that metabolomics can be used to monitor the impact of host diet on gut microbiota functionality. These data suggest that focusing on gut microbiota functionality may allow for a better characterization of the gut microbiota and its interaction with the host than only studying its composition. A new study, led by Dr. Tim Spector and…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados