Category : Ulcerative Colitis

Although the underlying mechanisms involved in inflammatory bowel disease (IBD) pathogenesis remain elusive, it is known that certain genes, which are shared by both Crohn’s disease (CD) and ulcerative colitis (UC) patients, may show a predisposition to the development of this disease. Furthermore, the intestinal bacterial and fungal microbiota might also drive disease pathogenesis and progression. Despite this knowledge, the…

GMFH Editing Team
GMFH Editing Team

Although the underlying mechanisms involved in inflammatory bowel disease (IBD) pathogenesis remain elusive, it is known that certain genes, which are shared by both Crohn’s disease (CD) and ulcerative colitis (UC) patients, may show a predisposition to the development of this disease. Furthermore, the intestinal bacterial and fungal microbiota might also drive disease pathogenesis and progression. Despite this knowledge, the…

GMFH Editing Team
GMFH Editing Team

Recent research has involved genetics, altered mucosal immune responses, environmental factors and the gut microbiome as major players in the development of inflammatory bowel disease (IBD). Given that some patients do not respond to conventional treatments, scientists are currently exploring new gut microbiome-targeted therapeutic approaches to improve disease course. A new study, led by Dr. Ramnik Joseph Xavier from the…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Recent research has involved genetics, altered mucosal immune responses, environmental factors and the gut microbiome as major players in the development of inflammatory bowel disease (IBD). Given that some patients do not respond to conventional treatments, scientists are currently exploring new gut microbiome-targeted therapeutic approaches to improve disease course. A new study, led by Dr. Ramnik Joseph Xavier from the…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

An imbalance in gut microbial communities has been associated with inflammatory bowel diseases (IBD) and research aimed at elucidating the contribution of the microbiota to inflammatory diseases has primarily focused on bacteria. Subsequent and ongoing research has characterized the fungal microbiota (called mycobiome) in patients with IBD. However, even though bacterial and fungal microbiota might be altered in IBD patients,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

An imbalance in gut microbial communities has been associated with inflammatory bowel diseases (IBD) and research aimed at elucidating the contribution of the microbiota to inflammatory diseases has primarily focused on bacteria. Subsequent and ongoing research has characterized the fungal microbiota (called mycobiome) in patients with IBD. However, even though bacterial and fungal microbiota might be altered in IBD patients,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Over millions of years, microbes that have colonized and coevolved with humans have gradually come to help regulate nutrition and metabolism processes and train both innate and adaptive immune responses. Among commensal microorganisms that colonize healthy individuals, pathobionts -including Helicobacter species- are those that can potentially induce chronic inflammatory responses in genetically susceptible hosts or in the presence of certain…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Over millions of years, microbes that have colonized and coevolved with humans have gradually come to help regulate nutrition and metabolism processes and train both innate and adaptive immune responses. Among commensal microorganisms that colonize healthy individuals, pathobionts -including Helicobacter species- are those that can potentially induce chronic inflammatory responses in genetically susceptible hosts or in the presence of certain…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Changes in the gut microbiota are involved in both homeostatic and inflammatory immune responses. T regulatory (Treg) immune cells tolerate diverse bacterial communities, whereas inflammatory conditions activate T effector (Teff) immune cells to react against the body’s own commensal microbiota. However, little is known regarding the role of commensal bacteria in inducing Teff cells during inflammation. A new study, led…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Changes in the gut microbiota are involved in both homeostatic and inflammatory immune responses. T regulatory (Treg) immune cells tolerate diverse bacterial communities, whereas inflammatory conditions activate T effector (Teff) immune cells to react against the body’s own commensal microbiota. However, little is known regarding the role of commensal bacteria in inducing Teff cells during inflammation. A new study, led…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

For those seeking the latest science on gut health and its applications to clinical practice, Paris was the place to be on March 11th and 12th, 2017. At the 6th GMFH World Summit, over 400 professionals from all over the world met to review the past decade of advances in gut microbiota science and where the field is headed in…

GMFH Editing Team
GMFH Editing Team

For those seeking the latest science on gut health and its applications to clinical practice, Paris was the place to be on March 11th and 12th, 2017. At the 6th GMFH World Summit, over 400 professionals from all over the world met to review the past decade of advances in gut microbiota science and where the field is headed in…

GMFH Editing Team
GMFH Editing Team

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Gut microbiome in Crohn’s disease (CD) and ulcerative colitis (UC), the two main forms of inflammatory bowel disease (IBD), has been previously shown to have a reduced microbial diversity and may play a role in their aetiology and pathogenesis. However, until now no clear comparison between dysbiosis in CD and in UC has been investigated in a large cohort. A…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Gut microbiome in Crohn’s disease (CD) and ulcerative colitis (UC), the two main forms of inflammatory bowel disease (IBD), has been previously shown to have a reduced microbial diversity and may play a role in their aetiology and pathogenesis. However, until now no clear comparison between dysbiosis in CD and in UC has been investigated in a large cohort. A…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados