Category : IBD

Recurrence of inflammatory lesions is frequent in patients undergoing ileal resection for Crohn’s disease (CD). Although male gender, active smoking at surgery and previous intestinal resection have all been associated with a higher risk of endoscopic post-operative recurrence—as assessed by ileocolonoscopy—there is not a single clinical risk factor that can be used as a perfect predictor of early postoperative endoscopic…

GMFH Editing Team
GMFH Editing Team

Recurrence of inflammatory lesions is frequent in patients undergoing ileal resection for Crohn’s disease (CD). Although male gender, active smoking at surgery and previous intestinal resection have all been associated with a higher risk of endoscopic post-operative recurrence—as assessed by ileocolonoscopy—there is not a single clinical risk factor that can be used as a perfect predictor of early postoperative endoscopic…

GMFH Editing Team
GMFH Editing Team

Although the underlying mechanisms involved in inflammatory bowel disease (IBD) pathogenesis remain elusive, it is known that certain genes, which are shared by both Crohn’s disease (CD) and ulcerative colitis (UC) patients, may show a predisposition to the development of this disease. Furthermore, the intestinal bacterial and fungal microbiota might also drive disease pathogenesis and progression. Despite this knowledge, the…

GMFH Editing Team
GMFH Editing Team

Although the underlying mechanisms involved in inflammatory bowel disease (IBD) pathogenesis remain elusive, it is known that certain genes, which are shared by both Crohn’s disease (CD) and ulcerative colitis (UC) patients, may show a predisposition to the development of this disease. Furthermore, the intestinal bacterial and fungal microbiota might also drive disease pathogenesis and progression. Despite this knowledge, the…

GMFH Editing Team
GMFH Editing Team

The use of complementary alternative medicine (CAM) is common among patients living with inflammatory bowel disease (IBD). For the purpose of this article, CAM is defined as therapies that go beyond traditional pharmacological approaches. Patients turn to CAM for many reasons, but most commonly the patient is either unhappy with their current treatment or is looking for a more holistic…

Natasha Haskey
Natasha Haskey is a Registered Dietitian and PhD student at The Centre for Microbiome and Inflammatory Research at the University of British Columbia – Okanagan (Kelowna, British Columbia, Canada). Her research work focuses on how dietary factors influence the gut microbiome, immune system and clinical disease in inflammatory bowel diseases. She is the co-author of the textbook Gut Microbiota: Interactive Effects on Nutrition and Health, which focuses on the gut microbiome as it relates to nutrition. Follow Natasha on Twitter @nhaskeyRD

The use of complementary alternative medicine (CAM) is common among patients living with inflammatory bowel disease (IBD). For the purpose of this article, CAM is defined as therapies that go beyond traditional pharmacological approaches. Patients turn to CAM for many reasons, but most commonly the patient is either unhappy with their current treatment or is looking for a more holistic…

Natasha Haskey
Natasha Haskey is a Registered Dietitian and PhD student at The Centre for Microbiome and Inflammatory Research at the University of British Columbia – Okanagan (Kelowna, British Columbia, Canada). Her research work focuses on how dietary factors influence the gut microbiome, immune system and clinical disease in inflammatory bowel diseases. She is the co-author of the textbook Gut Microbiota: Interactive Effects on Nutrition and Health, which focuses on the gut microbiome as it relates to nutrition. Follow Natasha on Twitter @nhaskeyRD

Recent research has involved genetics, altered mucosal immune responses, environmental factors and the gut microbiome as major players in the development of inflammatory bowel disease (IBD). Given that some patients do not respond to conventional treatments, scientists are currently exploring new gut microbiome-targeted therapeutic approaches to improve disease course. A new study, led by Dr. Ramnik Joseph Xavier from the…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Recent research has involved genetics, altered mucosal immune responses, environmental factors and the gut microbiome as major players in the development of inflammatory bowel disease (IBD). Given that some patients do not respond to conventional treatments, scientists are currently exploring new gut microbiome-targeted therapeutic approaches to improve disease course. A new study, led by Dr. Ramnik Joseph Xavier from the…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

An imbalance in gut microbial communities has been associated with inflammatory bowel diseases (IBD) and research aimed at elucidating the contribution of the microbiota to inflammatory diseases has primarily focused on bacteria. Subsequent and ongoing research has characterized the fungal microbiota (called mycobiome) in patients with IBD. However, even though bacterial and fungal microbiota might be altered in IBD patients,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

An imbalance in gut microbial communities has been associated with inflammatory bowel diseases (IBD) and research aimed at elucidating the contribution of the microbiota to inflammatory diseases has primarily focused on bacteria. Subsequent and ongoing research has characterized the fungal microbiota (called mycobiome) in patients with IBD. However, even though bacterial and fungal microbiota might be altered in IBD patients,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The enormous surface area of the human intestinal barrier is key to maintaining a delicate physiological homeostasis. On one hand, it must be optimized for absorption of water and nutrients; on the other hand, it must act as a tight barrier against chemical and microbial challenges - all while protecting us from unnecessary reactions to compounds that are harmful to…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

The enormous surface area of the human intestinal barrier is key to maintaining a delicate physiological homeostasis. On one hand, it must be optimized for absorption of water and nutrients; on the other hand, it must act as a tight barrier against chemical and microbial challenges - all while protecting us from unnecessary reactions to compounds that are harmful to…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

The fact that healthy relatives of patients with inflammatory bowel disease (IBD) have a higher risk of developing IBD and display mucosal microbiota dysbiosis indicates that both genetic background and alterations of the gut microbiome might trigger disease phenotype. A study, led by Prof. Kevin Whelan from the Faculty of Life Sciences & Medicine at King’s College London (United Kingdom),…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The fact that healthy relatives of patients with inflammatory bowel disease (IBD) have a higher risk of developing IBD and display mucosal microbiota dysbiosis indicates that both genetic background and alterations of the gut microbiome might trigger disease phenotype. A study, led by Prof. Kevin Whelan from the Faculty of Life Sciences & Medicine at King’s College London (United Kingdom),…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although recent research in humans has found that the gut microbiota follows a circadian rhythm in vitro and responds to fluctuations in the hormone melatonin, further studies in humans related to the circadian rhythms in vivo are necessary and the exact mechanisms accounting for the observed bacterial rhythms have not been shown yet. Moreover, the impact of timing of food…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although recent research in humans has found that the gut microbiota follows a circadian rhythm in vitro and responds to fluctuations in the hormone melatonin, further studies in humans related to the circadian rhythms in vivo are necessary and the exact mechanisms accounting for the observed bacterial rhythms have not been shown yet. Moreover, the impact of timing of food…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Over millions of years, microbes that have colonized and coevolved with humans have gradually come to help regulate nutrition and metabolism processes and train both innate and adaptive immune responses. Among commensal microorganisms that colonize healthy individuals, pathobionts -including Helicobacter species- are those that can potentially induce chronic inflammatory responses in genetically susceptible hosts or in the presence of certain…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Over millions of years, microbes that have colonized and coevolved with humans have gradually come to help regulate nutrition and metabolism processes and train both innate and adaptive immune responses. Among commensal microorganisms that colonize healthy individuals, pathobionts -including Helicobacter species- are those that can potentially induce chronic inflammatory responses in genetically susceptible hosts or in the presence of certain…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados