Category : Functional Disorders

Recently, an (open-access) article co-authored with colleagues Hans Törnblom & Magnus Simrén appeared in Nature Reviews Gastroenterology and Hepatology - Crosstalk at the mucosal border: importance of the gut microenvironment in IBS. This review addresses the complex pathophysiology of irritable bowel syndrome (IBS). We discuss four factors that may be involved: Gut microbiota composition Increased intestinal permeability Imbalance in the…

GMFH Editing Team
GMFH Editing Team

Recently, an (open-access) article co-authored with colleagues Hans Törnblom & Magnus Simrén appeared in Nature Reviews Gastroenterology and Hepatology - Crosstalk at the mucosal border: importance of the gut microenvironment in IBS. This review addresses the complex pathophysiology of irritable bowel syndrome (IBS). We discuss four factors that may be involved: Gut microbiota composition Increased intestinal permeability Imbalance in the…

GMFH Editing Team
GMFH Editing Team

While a lot of research in gut microbiota is focused on the bacterial community, little research data is available on the microeukaryotic community. Knowledge about the role of the microeukaryotic community in the gut and its interaction with the bacterial community and its host is insufficient (Anderson et al., 2013). One of the commonly observed microeukaryotes is Blastocystis. There is ongoing…

Sudarshan Shetty
PhD candidate at Wageningen UR, studying the human gut microbiome for understanding its role and function in human health.

While a lot of research in gut microbiota is focused on the bacterial community, little research data is available on the microeukaryotic community. Knowledge about the role of the microeukaryotic community in the gut and its interaction with the bacterial community and its host is insufficient (Anderson et al., 2013). One of the commonly observed microeukaryotes is Blastocystis. There is ongoing…

Sudarshan Shetty
PhD candidate at Wageningen UR, studying the human gut microbiome for understanding its role and function in human health.

The pathomechanism of Parkinson´s disease (PD) is well known but its origin is far from completely understood. The fact that among the prodromal signs of PD are constipation and a number of other (autonomically regulated) symptoms that occur years before the onset of movement disorders has given rise to the idea that a peripheral origin may exist. Since a-synuclein inclusions…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The pathomechanism of Parkinson´s disease (PD) is well known but its origin is far from completely understood. The fact that among the prodromal signs of PD are constipation and a number of other (autonomically regulated) symptoms that occur years before the onset of movement disorders has given rise to the idea that a peripheral origin may exist. Since a-synuclein inclusions…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

I participated in the "Targeting microbiota" congress at Pasteur Institute because I considered the topics discussed very interesting and relevant to my research. For me microbiome conferences are still a rather foreign territory, but I very much like to talk to people with a very different view from what I have. And my learning curve in the microbiome field is…

Filip Scheperjans
I am German and studied medicine at the Heinrich-Heine-University in Duesseldorf, Germany and was a visiting student at the National Hospital for Neurology and Neurosurgery in London and at the Mount Sinai Medical School in New York. During my studies I started work on my doctoral theses in the C & U Vogt Brain Research Institute about the microscopical and neurochemical anatomy of the human parietal lobe. After graduating, I continued work on my thesis at the Institute of Medicine at the Research Center in Juelich. I received my doctoral degree and my thesis was awarded the best medical thesis in 2008 at Duesseldorf University. In 2007 I moved to Finland and started my clinical specialization in neurology. During this period I completed a 6 month fellowship in our clinical stroke research lab which gave me experience in the planning and conduction of clinical trials. I received my specialist degree in 2013.

I participated in the "Targeting microbiota" congress at Pasteur Institute because I considered the topics discussed very interesting and relevant to my research. For me microbiome conferences are still a rather foreign territory, but I very much like to talk to people with a very different view from what I have. And my learning curve in the microbiome field is…

Filip Scheperjans
I am German and studied medicine at the Heinrich-Heine-University in Duesseldorf, Germany and was a visiting student at the National Hospital for Neurology and Neurosurgery in London and at the Mount Sinai Medical School in New York. During my studies I started work on my doctoral theses in the C & U Vogt Brain Research Institute about the microscopical and neurochemical anatomy of the human parietal lobe. After graduating, I continued work on my thesis at the Institute of Medicine at the Research Center in Juelich. I received my doctoral degree and my thesis was awarded the best medical thesis in 2008 at Duesseldorf University. In 2007 I moved to Finland and started my clinical specialization in neurology. During this period I completed a 6 month fellowship in our clinical stroke research lab which gave me experience in the planning and conduction of clinical trials. I received my specialist degree in 2013.

In this contribution, GMFH board member Mary Ellen Sanders analyzes one of our recent website selections:  Veiga et al. (2014) Changes of the human gut microbiome induced by a fermented milk product. Probiotics are a promising means to manipulate the microbiome, but there is little evidence that they can do this by changing the microbiota composition. Yes, the genus or…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

In this contribution, GMFH board member Mary Ellen Sanders analyzes one of our recent website selections:  Veiga et al. (2014) Changes of the human gut microbiome induced by a fermented milk product. Probiotics are a promising means to manipulate the microbiome, but there is little evidence that they can do this by changing the microbiota composition. Yes, the genus or…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

Professor Mihai Pop, of University of Maryland Institute for Advanced Computer Studies, recently co-authored a paper entitled Diarrhea in young children from low-income countries leads to large-scale alterations in intestinal microbiota composition. He took the time to speak with Gut Microbiota for Health about this study. Why is it important to understand what causes diarrhea? Our study is part of a…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Professor Mihai Pop, of University of Maryland Institute for Advanced Computer Studies, recently co-authored a paper entitled Diarrhea in young children from low-income countries leads to large-scale alterations in intestinal microbiota composition. He took the time to speak with Gut Microbiota for Health about this study. Why is it important to understand what causes diarrhea? Our study is part of a…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Dr. Stephen Collins is a gastroenterologist and a researcher at McMaster University in Canada. Collins’ recent studies on the functional relevance of the gut microbiota, in collaboration with Dr. R. DePalma & Dr. P. Bercik, were recently presented at the American Gastroenterological Society’s annual meeting. Meanwhile, in April 2014, his review of the role of the gut microbiota in Irritable…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Dr. Stephen Collins is a gastroenterologist and a researcher at McMaster University in Canada. Collins’ recent studies on the functional relevance of the gut microbiota, in collaboration with Dr. R. DePalma & Dr. P. Bercik, were recently presented at the American Gastroenterological Society’s annual meeting. Meanwhile, in April 2014, his review of the role of the gut microbiota in Irritable…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Professor Barbara’s main scientific interest is in functional gastrointestinal disorders, including constipation, irritable bowel syndrome and diarrhea. These conditions have been considered for a long time mood disorders. However, there is clear recognition that peripheral and environmental factors as well as the intestinal microbiota participate to their pathophysiology. Subsets of patients develop these condition after a bout of infectious gastroenteritis,…

GMFH Editing Team
GMFH Editing Team

Professor Barbara’s main scientific interest is in functional gastrointestinal disorders, including constipation, irritable bowel syndrome and diarrhea. These conditions have been considered for a long time mood disorders. However, there is clear recognition that peripheral and environmental factors as well as the intestinal microbiota participate to their pathophysiology. Subsets of patients develop these condition after a bout of infectious gastroenteritis,…

GMFH Editing Team
GMFH Editing Team

One year at a glance is the compilation of the most relevant and popular content on gut microbiota as published on the GMFH website.   The topic is rapidly growing across all fields of expertise and questions it raises are endless. It seems that hardly a day goes without gut microbiota being related to the health status (enterotypes, second genotype, ageing),…

GMFH Editing Team
GMFH Editing Team

One year at a glance is the compilation of the most relevant and popular content on gut microbiota as published on the GMFH website.   The topic is rapidly growing across all fields of expertise and questions it raises are endless. It seems that hardly a day goes without gut microbiota being related to the health status (enterotypes, second genotype, ageing),…

GMFH Editing Team
GMFH Editing Team

(Berlin, October 16, 2013) Clinicians with gastrointestinal (GI) patients often wish – and are asked by their patients – to recommend specific probiotics. However, a clear and accessible evidence-based reference guide on the role and effectiveness of specific probiotics and their clinical use for managing particular lower gastrointestinal problems has been lacking so far. Now a new reference guide, which…

GMFH Editing Team
GMFH Editing Team

(Berlin, October 16, 2013) Clinicians with gastrointestinal (GI) patients often wish – and are asked by their patients – to recommend specific probiotics. However, a clear and accessible evidence-based reference guide on the role and effectiveness of specific probiotics and their clinical use for managing particular lower gastrointestinal problems has been lacking so far. Now a new reference guide, which…

GMFH Editing Team
GMFH Editing Team