While the idea that our gut can influence our brain is not new, this is a rapidly growing area of research. Find out more on how gut microbes influence anxiety and stress and why tackling these psychological traits matters for irritable bowel syndrome.

Non-prescription therapeutics for IBS: where are we?

30 Jan 2024

by Andrea Costantino

Alterations in the gut microbiome composition and functions are emerging as a potential target for managing IBS. Discover how microbiota-modifying treatments, including prebiotics, probiotics, antibiotics, and fecal microbiota transplantation, hold promise in alleviating symptoms of this vexing condition.

Where are we on microbiome-based therapies in disorders of gut-brain interaction?

4 Dec 2023

by Andreu Prados, Rene van den Wijngaard

NeuroGASTRO 2023, the leading meeting in Europe held by ESNM on the latest developments in neurogastroenterology, digestive motility, and disorders of gut-brain interaction, took place from August 31st to September 2nd, 2023. Find out more about the main takeaways from the role of fecal microbiota transplants, microbial consortia and probiotics in disorders of gut-brain interaction picked up by GMFH editors (Part 2).

NeuroGASTRO 2023, the leading meeting in Europe held by ESNM on the latest developments in neurogastroenterology, digestive motility, and disorders of the gut-brain interaction, took place from August 31st to September 2nd, 2023. Find out more what the latest research says about the involvement of the intestinal microbiota, mast cells, eosinophils and gut barrier in disorders of gut-brain interaction and dietary considerations in their management picked up by GMFH editors (Part 1).

Chronic abdominal pain, diarrhea, constipation, and bloating are common gastrointestinal symptoms. While a structural or an organic disease can be suspected because of the symptoms and is often easy to be diagnosed by endoscopy or imaging methods, sometimes gastrointestinal symptoms are not related to any alteration that may be seen through diagnostic techniques, and consequently have been classified under the umbrella of “disorders of gut-brain interaction”.

Bacteria and fungi in the human gut microbiota may contribute to the underlying mechanisms of IBS, which means the latter can be explored as a potential target for IBS. This article explores what is known about the role of the gut microbiome and yeast probiotics in irritable bowel syndrome.

Little is known about the relationship between diet, the composition and function of the gut microbiota and clinical symptoms of IBS. New findings identify how IBS symptom severity is related to a higher intake of foods with poor nutritional quality and gut microbiome features at both subspecies level and metabolic pathways involved in carbohydrate metabolism.

Analysing the molecular and biochemical mechanisms disturbing the complex network of communication is key to our understanding of the pathophysiology of the functional GI disorders. Together with ESNM we have prepared an exciting webinar series under the topic: Microbiota and Gut-Brain Connection: A new Frontier in Neurogastroenterology. This free resource is a great opportunity to hear leading worldwide experts presenting the most recent findings on this topic.

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