Category : Cancer & Tumors

Yava L. Jones-Hall, Ariangela Kozik and Cindy Nakatsu from Purdue University, West Lafayette, Indiana, USA, have recently published a paper in PLoS ONE on the role of Tumor Necrosis Factor (TNF) in Inflammatory Bowel Disease (IBD) and the impact of this pro-inflammatory cytokine on the gut microbiota. The data presented in this paper show that TNF contributes to the local inflammation…

GMFH Editing Team
GMFH Editing Team

Yava L. Jones-Hall, Ariangela Kozik and Cindy Nakatsu from Purdue University, West Lafayette, Indiana, USA, have recently published a paper in PLoS ONE on the role of Tumor Necrosis Factor (TNF) in Inflammatory Bowel Disease (IBD) and the impact of this pro-inflammatory cytokine on the gut microbiota. The data presented in this paper show that TNF contributes to the local inflammation…

GMFH Editing Team
GMFH Editing Team

Do specific microbiota determine levels of specific metabolites? How does the metabolite profile develop during establishment of the microbiome in infants? Can we assess an individual’s physiological state based on gut flora and metabolites? These questions are key to translating scientific findings related to intestinal metabolites in order to bring them to the clinic. The relatively new scientific field of…

Stefan Jellbauer
Stefan Jellbauer is a Field Application Scientist in the Biotech industry. Previously, he was an ORISE fellow at the Food Safety division of the FDA and a Postdoc in Manuela Raffatellu’s lab at University of California, Irvine, where he studied host-pathogen interactions and mucosal immunology. He obtained his PhD in 2010 from Ludwig-Maximilians University in Munich, Germany.

Do specific microbiota determine levels of specific metabolites? How does the metabolite profile develop during establishment of the microbiome in infants? Can we assess an individual’s physiological state based on gut flora and metabolites? These questions are key to translating scientific findings related to intestinal metabolites in order to bring them to the clinic. The relatively new scientific field of…

Stefan Jellbauer
Stefan Jellbauer is a Field Application Scientist in the Biotech industry. Previously, he was an ORISE fellow at the Food Safety division of the FDA and a Postdoc in Manuela Raffatellu’s lab at University of California, Irvine, where he studied host-pathogen interactions and mucosal immunology. He obtained his PhD in 2010 from Ludwig-Maximilians University in Munich, Germany.

The higher rates of colon cancer in Americans of African origin compared to South Africans are usually attributed to diets containing more animal protein and fat and less fibre. O'Keefe et al. investigated (in a paper published in Nature Communications) the role of fat and fibre in this association by conducting 2-week-long food changes in volunteers from both populations: African-Americans…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The higher rates of colon cancer in Americans of African origin compared to South Africans are usually attributed to diets containing more animal protein and fat and less fibre. O'Keefe et al. investigated (in a paper published in Nature Communications) the role of fat and fibre in this association by conducting 2-week-long food changes in volunteers from both populations: African-Americans…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Keku et al. recently published a review called "The Gastrointestinal Microbiota and Colorectal Cancer" in the American Journal of Physiology - Gastrointestinal and Liver Physiology. Although genes contribute to colorectal cancer (CRC), the gut microbiota are an important player. Correlational studies have observed changes in fecal microbiota composition in CRC compared to healthy controls; cancer is associated with reduced abundances…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Keku et al. recently published a review called "The Gastrointestinal Microbiota and Colorectal Cancer" in the American Journal of Physiology - Gastrointestinal and Liver Physiology. Although genes contribute to colorectal cancer (CRC), the gut microbiota are an important player. Correlational studies have observed changes in fecal microbiota composition in CRC compared to healthy controls; cancer is associated with reduced abundances…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Prof. Iradj Sobhani is a physician in the Department of Gastroenterology at Assistance Publique-Hôpitaux de Paris, and a professor of medicine at University Paris-Est Créteil, in France. He is the director of the interdisciplinary research team Macbeth-EC2M3 (Microbiota and early colon cancer detection by using multimodal molecular markers). He and his co-authors recently published a paper in Molecular Systems Biology called 'Potential of fecal…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Prof. Iradj Sobhani is a physician in the Department of Gastroenterology at Assistance Publique-Hôpitaux de Paris, and a professor of medicine at University Paris-Est Créteil, in France. He is the director of the interdisciplinary research team Macbeth-EC2M3 (Microbiota and early colon cancer detection by using multimodal molecular markers). He and his co-authors recently published a paper in Molecular Systems Biology called 'Potential of fecal…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

I participated to the conference "Targeting Microbiota" to update my knowledge concerning the gut microbiota and to foster collaborations with other scientists in the field. It was also a great opportunity to present my ongoing work. This congress was scientifically very fruitful. I was impressed by the quality of the invited speakers. The congress covered a broad panel of pathologies…

Laure Bindels
I am a PharmD with a PhD in Pharmaceutical Sciences. I did my PhD in nutrition and metabolism in the lab of Prof Delzenne (Université catholique de Louvain), working on the interest of gut microbiota modulation in the control of cancer progression and associated cachexia. I spent a year as a Postdoctoral Research Associate at the University of Nebraska-Lincoln (Prof Ramer-Tait and Prof Jens Walter) working on resistant starches and gut microbiota, where I acquired skills in gnotobiology and bioinformatics analysis. I am now a FNRS Postdoctoral fellow in the lab of Prof Delzenne.

I participated to the conference "Targeting Microbiota" to update my knowledge concerning the gut microbiota and to foster collaborations with other scientists in the field. It was also a great opportunity to present my ongoing work. This congress was scientifically very fruitful. I was impressed by the quality of the invited speakers. The congress covered a broad panel of pathologies…

Laure Bindels
I am a PharmD with a PhD in Pharmaceutical Sciences. I did my PhD in nutrition and metabolism in the lab of Prof Delzenne (Université catholique de Louvain), working on the interest of gut microbiota modulation in the control of cancer progression and associated cachexia. I spent a year as a Postdoctoral Research Associate at the University of Nebraska-Lincoln (Prof Ramer-Tait and Prof Jens Walter) working on resistant starches and gut microbiota, where I acquired skills in gnotobiology and bioinformatics analysis. I am now a FNRS Postdoctoral fellow in the lab of Prof Delzenne.

In a study published in Cancer Prevention Research, Dr. Patrick Schloss (University of Michigan) and his team found that the gut microbiome could enrich current methods of testing for colon cancer. The group characterized the gut microbiome from stool samples of patients in three stages of colorectal cancer development: healthy, adenoma, and carcinoma. They found distinct features of the bacterial populations…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

In a study published in Cancer Prevention Research, Dr. Patrick Schloss (University of Michigan) and his team found that the gut microbiome could enrich current methods of testing for colon cancer. The group characterized the gut microbiome from stool samples of patients in three stages of colorectal cancer development: healthy, adenoma, and carcinoma. They found distinct features of the bacterial populations…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

In this study, Aviles-Jimenez and co-workers aimed to characterize microbiota of the gastric mucosa as its progress to intestinal type of cancer. To do that, they analysed gastric tissue in patients with non-atrophic gastritis (NAG), intestinal metaplasia (IM) and intestinal-type gastric cancer (GC). After performing genetic analyses on the samples, the researchers quantified a low bacterial diversity in all samples,…

GMFH Editing Team
GMFH Editing Team

In this study, Aviles-Jimenez and co-workers aimed to characterize microbiota of the gastric mucosa as its progress to intestinal type of cancer. To do that, they analysed gastric tissue in patients with non-atrophic gastritis (NAG), intestinal metaplasia (IM) and intestinal-type gastric cancer (GC). After performing genetic analyses on the samples, the researchers quantified a low bacterial diversity in all samples,…

GMFH Editing Team
GMFH Editing Team

Science’s editors named “Our Microbes, Our Health” as runner-up for Breakthrough of the Year 2013.   This Science Magazine “News” article highlighted some studies on gut microbiota, published in several magazines in 2013. It represented a good collection of some of the most important findings involving microbioma and health. Among the selected topics, we could find studies connecting gut microbiota…

GMFH Editing Team
GMFH Editing Team

Science’s editors named “Our Microbes, Our Health” as runner-up for Breakthrough of the Year 2013.   This Science Magazine “News” article highlighted some studies on gut microbiota, published in several magazines in 2013. It represented a good collection of some of the most important findings involving microbioma and health. Among the selected topics, we could find studies connecting gut microbiota…

GMFH Editing Team
GMFH Editing Team

[This article is an outside contribution by Dr Patricia Lepage (INRA), co-author of the paper. For further references about the author, see the short bio hereunder]   Research jointly conducted by investigators at Institut Gustave Roussy, Inserm, Institut Pasteur and INRA (National Agronomic Research Institute) in France has led to a rather surprising discovery on the manner in which cancer…

GMFH Editing Team
GMFH Editing Team

[This article is an outside contribution by Dr Patricia Lepage (INRA), co-author of the paper. For further references about the author, see the short bio hereunder]   Research jointly conducted by investigators at Institut Gustave Roussy, Inserm, Institut Pasteur and INRA (National Agronomic Research Institute) in France has led to a rather surprising discovery on the manner in which cancer…

GMFH Editing Team
GMFH Editing Team