Category : Digestive Health

Mutations that lead to an impairment of tet methylcytosine dioxygenase 2 (Tet2) function or/and expression -  a gene that encodes an epigenetic modifier enzyme - have been related to the development of haematopoietic malignancies in both mice and humans. According to a new study in Nature by Marlies Meisel and Reinhard Hinterleitner from the University of Chicago and collaborators, gut…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Mutations that lead to an impairment of tet methylcytosine dioxygenase 2 (Tet2) function or/and expression -  a gene that encodes an epigenetic modifier enzyme - have been related to the development of haematopoietic malignancies in both mice and humans. According to a new study in Nature by Marlies Meisel and Reinhard Hinterleitner from the University of Chicago and collaborators, gut…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

An imbalance in gut microbial communities has been associated with inflammatory bowel diseases (IBD) and research aimed at elucidating the contribution of the microbiota to inflammatory diseases has primarily focused on bacteria. Subsequent and ongoing research has characterized the fungal microbiota (called mycobiome) in patients with IBD. However, even though bacterial and fungal microbiota might be altered in IBD patients,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

An imbalance in gut microbial communities has been associated with inflammatory bowel diseases (IBD) and research aimed at elucidating the contribution of the microbiota to inflammatory diseases has primarily focused on bacteria. Subsequent and ongoing research has characterized the fungal microbiota (called mycobiome) in patients with IBD. However, even though bacterial and fungal microbiota might be altered in IBD patients,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that some subgroups of patients with irritable bowel syndrome (IBS) exhibit a different gut microbiota composition. Although previous small not blinded studies and one randomized placebo-controlled study have looked at the effectiveness of fecal microbiota transplantation (FMT) in patients with IBS, its utility in these patients remains unknown. A new randomized, double-blind placebo-controlled study, led by…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Previous research has shown that some subgroups of patients with irritable bowel syndrome (IBS) exhibit a different gut microbiota composition. Although previous small not blinded studies and one randomized placebo-controlled study have looked at the effectiveness of fecal microbiota transplantation (FMT) in patients with IBS, its utility in these patients remains unknown. A new randomized, double-blind placebo-controlled study, led by…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The enormous surface area of the human intestinal barrier is key to maintaining a delicate physiological homeostasis. On one hand, it must be optimized for absorption of water and nutrients; on the other hand, it must act as a tight barrier against chemical and microbial challenges - all while protecting us from unnecessary reactions to compounds that are harmful to…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

The enormous surface area of the human intestinal barrier is key to maintaining a delicate physiological homeostasis. On one hand, it must be optimized for absorption of water and nutrients; on the other hand, it must act as a tight barrier against chemical and microbial challenges - all while protecting us from unnecessary reactions to compounds that are harmful to…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

Patients with gastrointestinal diseases often experience symptoms (diarrhea, constipation, abdominal pain, bloating) that worsen after a meal. They draw linkages between what they eat and negative consequences for their well-being. In an attempt to self-manage, patients often end up removing foods from their diet that are needed for nutritional health. They turn to their medical practitioners for information and support…

Andrea Hardy
Registered Dietitian, Andrea Hardy from Calgary, Canada specializes in gastrointestinal disorders and the gut microbiome. She is recognized as Canada’s gut health dietitian – educating health care professionals and the public on the pivotal role nutrition plays in gut health. You can find her at Ignite Nutrition, or on Twitter (@AndreaHardyRD).

Patients with gastrointestinal diseases often experience symptoms (diarrhea, constipation, abdominal pain, bloating) that worsen after a meal. They draw linkages between what they eat and negative consequences for their well-being. In an attempt to self-manage, patients often end up removing foods from their diet that are needed for nutritional health. They turn to their medical practitioners for information and support…

Andrea Hardy
Registered Dietitian, Andrea Hardy from Calgary, Canada specializes in gastrointestinal disorders and the gut microbiome. She is recognized as Canada’s gut health dietitian – educating health care professionals and the public on the pivotal role nutrition plays in gut health. You can find her at Ignite Nutrition, or on Twitter (@AndreaHardyRD).

While changes in the human gut microbiome's composition and function have been related to several diseases and types of medication, variability between studies limits the comparing of findings. Another factor that limits our understanding of how disease-medication interactions have an impact on gut microbiota is the fact that the gut microbiome has been studied in relation to single diseases without…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

While changes in the human gut microbiome's composition and function have been related to several diseases and types of medication, variability between studies limits the comparing of findings. Another factor that limits our understanding of how disease-medication interactions have an impact on gut microbiota is the fact that the gut microbiome has been studied in relation to single diseases without…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The fact that healthy relatives of patients with inflammatory bowel disease (IBD) have a higher risk of developing IBD and display mucosal microbiota dysbiosis indicates that both genetic background and alterations of the gut microbiome might trigger disease phenotype. A study, led by Prof. Kevin Whelan from the Faculty of Life Sciences & Medicine at King’s College London (United Kingdom),…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The fact that healthy relatives of patients with inflammatory bowel disease (IBD) have a higher risk of developing IBD and display mucosal microbiota dysbiosis indicates that both genetic background and alterations of the gut microbiome might trigger disease phenotype. A study, led by Prof. Kevin Whelan from the Faculty of Life Sciences & Medicine at King’s College London (United Kingdom),…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Metabolites produced by the gut microbiota may affect host physiology both directly and indirectly. Tryptophan is an essential amino acid and a precursor to several such metabolites. Tryptamine is important example of a bacterially-produced, tryptophan-derived metabolite with previously unknown functions in the gastrointestinal tract. A new study, published in Cell Host & Microbe and led by Dr. Purna C. Kashyap…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

Metabolites produced by the gut microbiota may affect host physiology both directly and indirectly. Tryptophan is an essential amino acid and a precursor to several such metabolites. Tryptamine is important example of a bacterially-produced, tryptophan-derived metabolite with previously unknown functions in the gastrointestinal tract. A new study, published in Cell Host & Microbe and led by Dr. Purna C. Kashyap…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

How the gut microbiota can relate to preventing and treating obesity and what are the potential gut microbiota targets in gluten-related disorders were the key subjects discussed in the workshop on nutrition organized by GMFH during the Gut Microbiota for Health World Summit 2018, held in Rome on March 10 and 11. The workshop, called ‘Gut microbiota targets in nutrition’,…

GMFH Editing Team
GMFH Editing Team

How the gut microbiota can relate to preventing and treating obesity and what are the potential gut microbiota targets in gluten-related disorders were the key subjects discussed in the workshop on nutrition organized by GMFH during the Gut Microbiota for Health World Summit 2018, held in Rome on March 10 and 11. The workshop, called ‘Gut microbiota targets in nutrition’,…

GMFH Editing Team
GMFH Editing Team

Mice models are widely used to assess the impact of exposure to environmental factors such as chemicals, drugs or infectious agents on host homeostasis through modulation of the gut microbiota. A new study, led by Dr. Guodong Zhang from the University of Massachusetts (USA), has found that exposure to triclosan increases colonic inflammation and colitis-associated colon tumorigenesis in mice. Triclosan…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Mice models are widely used to assess the impact of exposure to environmental factors such as chemicals, drugs or infectious agents on host homeostasis through modulation of the gut microbiota. A new study, led by Dr. Guodong Zhang from the University of Massachusetts (USA), has found that exposure to triclosan increases colonic inflammation and colitis-associated colon tumorigenesis in mice. Triclosan…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados