Category : Digestive Health

Although nowadays diet plays only a small part in published guidelines for managing inflammatory bowel diseases (IBDs), there is an increasing amount of evidence that supports the role of diet in patients with IBD, especially at early stages. Evidence of diet modulating intestinal inflammation comes mainly from mice studies. An elegant mice study published in 2018 examined the effects of…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Although nowadays diet plays only a small part in published guidelines for managing inflammatory bowel diseases (IBDs), there is an increasing amount of evidence that supports the role of diet in patients with IBD, especially at early stages. Evidence of diet modulating intestinal inflammation comes mainly from mice studies. An elegant mice study published in 2018 examined the effects of…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Macronutrients, micronutrients and non-nutritive compounds are major drivers of the composition and metabolic functions of gut microbial communities. However, nutrient composition alone cannot explain the way people’s gut microbiomes are so different to each other. One feature that distinguishes humans from other species is our ability to heat-treat our meals. This process alters nutrients and makes foods more digestible, while…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Macronutrients, micronutrients and non-nutritive compounds are major drivers of the composition and metabolic functions of gut microbial communities. However, nutrient composition alone cannot explain the way people’s gut microbiomes are so different to each other. One feature that distinguishes humans from other species is our ability to heat-treat our meals. This process alters nutrients and makes foods more digestible, while…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Crohn’s Disease (CD) is one of the sets of inflammatory bowel disease (IBD) that consists of chronic inflammation of the terminal ileum, that can extend throughout the gastrointestinal tract. Researchers have focused more on the role the gut microbiota plays in CD over the years to better understand disease progression. Increased endotoxemia, inflammation, fungal loads and changes in the gut…

Allison Clark
Allison Clark has a master in nutrition and health from Open University in Barcelona and a master in journalism. She is a freelance writer and nutritionist and has written various peer review papers about the role the gut microbiota plays in health, disease and endurance exercise performance. Allison is passionate about the role diet and the gut microbiota play in health and disease. Follow her on Twitter @Heal_your_Gut

Crohn’s Disease (CD) is one of the sets of inflammatory bowel disease (IBD) that consists of chronic inflammation of the terminal ileum, that can extend throughout the gastrointestinal tract. Researchers have focused more on the role the gut microbiota plays in CD over the years to better understand disease progression. Increased endotoxemia, inflammation, fungal loads and changes in the gut…

Allison Clark
Allison Clark has a master in nutrition and health from Open University in Barcelona and a master in journalism. She is a freelance writer and nutritionist and has written various peer review papers about the role the gut microbiota plays in health, disease and endurance exercise performance. Allison is passionate about the role diet and the gut microbiota play in health and disease. Follow her on Twitter @Heal_your_Gut

With the huge amount of press coverage of the effectiveness of probiotics and prebiotics as a way to improve human health and wellbeing, it’s difficult to keep abreast of everything that’s going on in the field. A recent narrative review, authored by five of the world’s leading scientists in the field, summarizes the clinical application and use in humans of…

GMFH Editing Team
GMFH Editing Team

With the huge amount of press coverage of the effectiveness of probiotics and prebiotics as a way to improve human health and wellbeing, it’s difficult to keep abreast of everything that’s going on in the field. A recent narrative review, authored by five of the world’s leading scientists in the field, summarizes the clinical application and use in humans of…

GMFH Editing Team
GMFH Editing Team

Numerous claims are currently being made about different dietary patterns as a means of ensuring optimal gut health. Even so, their effectiveness and safety are not always supported by scientific evidence. The Paleolithic (or ‘paleo’) diet is often promoted as a means of improving gut health. But despite its popularity, the science-based long-term effects of this diet remain unknown. A…

GMFH Editing Team
GMFH Editing Team

Numerous claims are currently being made about different dietary patterns as a means of ensuring optimal gut health. Even so, their effectiveness and safety are not always supported by scientific evidence. The Paleolithic (or ‘paleo’) diet is often promoted as a means of improving gut health. But despite its popularity, the science-based long-term effects of this diet remain unknown. A…

GMFH Editing Team
GMFH Editing Team

The fact some people respond to a drug treatment while for others the same treatment is totally ineffective may depend on our gut microbiota. In other words, after a drug is administered orally, it could either be absorbed into the bloodstream and metabolized by the liver, or it remains in the intestine where it can be metabolized by the gut…

GMFH Editing Team
GMFH Editing Team

The fact some people respond to a drug treatment while for others the same treatment is totally ineffective may depend on our gut microbiota. In other words, after a drug is administered orally, it could either be absorbed into the bloodstream and metabolized by the liver, or it remains in the intestine where it can be metabolized by the gut…

GMFH Editing Team
GMFH Editing Team

Imbalances in the small intestinal microbiome can drive clinical consequences in the form of small intestinal bacterial overgrowth (SIBO), characterized by higher numbers of bacteria and a distribution more commonly associated with the colon. In recent times, SIBO has been recognized as a frequent cause of common gastrointestinal conditions that share risk factors such as maldigestion and malabsorption. Methods used…

GMFH Editing Team
GMFH Editing Team

Imbalances in the small intestinal microbiome can drive clinical consequences in the form of small intestinal bacterial overgrowth (SIBO), characterized by higher numbers of bacteria and a distribution more commonly associated with the colon. In recent times, SIBO has been recognized as a frequent cause of common gastrointestinal conditions that share risk factors such as maldigestion and malabsorption. Methods used…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

The gut microbiota has become a new player in the onset and development of metabolic syndrome and its associated pathologies. One gut bacterium that has been positively associated with leanness in mice and humans is Akkermansia muciniphila, which is naturally present in the gut microbiota of healthy people. In 2017, our research team at UCLouvain (Belgium) found that a pasteurized…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

The gut microbiota has become a new player in the onset and development of metabolic syndrome and its associated pathologies. One gut bacterium that has been positively associated with leanness in mice and humans is Akkermansia muciniphila, which is naturally present in the gut microbiota of healthy people. In 2017, our research team at UCLouvain (Belgium) found that a pasteurized…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

The enteric nervous system (ENS)—also called “our second brain”—is an autonomous part of the nervous system consisting of in the myenteric and submucosal plexus within the wall of the gastrointestinal tract. Comprising primary afferent neurons, interneurons and motor neurons, alongside intestinal cells involved in immune responses and endocrine and paracrine functions, it is involved in the sensory-motor control of the…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The enteric nervous system (ENS)—also called “our second brain”—is an autonomous part of the nervous system consisting of in the myenteric and submucosal plexus within the wall of the gastrointestinal tract. Comprising primary afferent neurons, interneurons and motor neurons, alongside intestinal cells involved in immune responses and endocrine and paracrine functions, it is involved in the sensory-motor control of the…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.