Category : Research & Practice

A major focus of gut microbiome research in early life is how delivery mode affects the newborn gut microbiota and its impact on the health of the growing child. Although previous studies revealed that infants born by Caesarean section (C-section) develop a gut microbiota composition that more closely resembles adult skin and the hospital environment, and which may predispose newborns…

GMFH Editing Team
GMFH Editing Team

A major focus of gut microbiome research in early life is how delivery mode affects the newborn gut microbiota and its impact on the health of the growing child. Although previous studies revealed that infants born by Caesarean section (C-section) develop a gut microbiota composition that more closely resembles adult skin and the hospital environment, and which may predispose newborns…

GMFH Editing Team
GMFH Editing Team

The symbiotic relationship between host and microbes starts early in life and is important not only in terms of how the neonate microbiome ultimately develops, but also its potential impact on long-term infant health. A current ongoing debate within the scientific community is whether gut colonization starts during pregnancy or at birth. Indeed, the crucial question of when bacteria first…

Joël Doré
Research Director at the French Research Institute in Agricultural Sciences, INRA, Dr. Joël Doré is currently President of the Executive Committee of the Pre-Industrial Demonstrator MetaGenoPolis, a platform of excellence dedicated to quantitative and functional metagenomics, funded by the French government Futures Investments. He is Deputy Head of the MICALIS institute “Food and Gut Microbiology for Human Health” and scientific board member of Microbiology Pole of the Doctoral School “Therapeutic Innovations” at Paris-XI University. Joël Doré received his PhD from the University of Illinois at Urbana-Champaign, USA, in 1988. His main research interest is the molecular assessment of the human intestinal microbiota in health and disease and metagenomic investigation of the molecular cross-talk between intestinal bacteria and human cells. Dr. Doré has published >120 publications in peer reviewed scientific journals. His goal is to provide a better understanding of the intestinal ecosystem in order to support therapeutic choices in the medical area, as well as health claims for functional foods.

The symbiotic relationship between host and microbes starts early in life and is important not only in terms of how the neonate microbiome ultimately develops, but also its potential impact on long-term infant health. A current ongoing debate within the scientific community is whether gut colonization starts during pregnancy or at birth. Indeed, the crucial question of when bacteria first…

Joël Doré
Research Director at the French Research Institute in Agricultural Sciences, INRA, Dr. Joël Doré is currently President of the Executive Committee of the Pre-Industrial Demonstrator MetaGenoPolis, a platform of excellence dedicated to quantitative and functional metagenomics, funded by the French government Futures Investments. He is Deputy Head of the MICALIS institute “Food and Gut Microbiology for Human Health” and scientific board member of Microbiology Pole of the Doctoral School “Therapeutic Innovations” at Paris-XI University. Joël Doré received his PhD from the University of Illinois at Urbana-Champaign, USA, in 1988. His main research interest is the molecular assessment of the human intestinal microbiota in health and disease and metagenomic investigation of the molecular cross-talk between intestinal bacteria and human cells. Dr. Doré has published >120 publications in peer reviewed scientific journals. His goal is to provide a better understanding of the intestinal ecosystem in order to support therapeutic choices in the medical area, as well as health claims for functional foods.

A lack of sun exposure/UVB radiation has been linked to a decrease in vitamin D synthesis, which has been hypothesized to be one of the environmental factors related to the current rise in immune-related conditions through involving the gut microbiota. However, mouse and small human observational studies that showed associations between vitamin D and the gut microbiome do not allow…

GMFH Editing Team
GMFH Editing Team

A lack of sun exposure/UVB radiation has been linked to a decrease in vitamin D synthesis, which has been hypothesized to be one of the environmental factors related to the current rise in immune-related conditions through involving the gut microbiota. However, mouse and small human observational studies that showed associations between vitamin D and the gut microbiome do not allow…

GMFH Editing Team
GMFH Editing Team

Recurrent abdominal pain, which refers to functional abdominal pain disorders under the Rome IV classification, is a common problem affecting up to 25% of school-age children. As an organic cause is missing with this condition, parents of children affected by functional abdominal pain consider diet and behavioral therapies as methods of managing recurring problems. Although the treatment of functional abdominal…

GMFH Editing Team
GMFH Editing Team

Recurrent abdominal pain, which refers to functional abdominal pain disorders under the Rome IV classification, is a common problem affecting up to 25% of school-age children. As an organic cause is missing with this condition, parents of children affected by functional abdominal pain consider diet and behavioral therapies as methods of managing recurring problems. Although the treatment of functional abdominal…

GMFH Editing Team
GMFH Editing Team

Synbiotics are substances that combine a probiotic and prebiotic. While Gibson and Roberfroid were the first to anticipate that the two could be combined as synbiotics back in 1995, research in the field has accelerated over the past decade. The reported scientific literature on synbiotics includes a wide range of studies carried out under different conditions. Recent human trials have…

GMFH Editing Team
GMFH Editing Team

Synbiotics are substances that combine a probiotic and prebiotic. While Gibson and Roberfroid were the first to anticipate that the two could be combined as synbiotics back in 1995, research in the field has accelerated over the past decade. The reported scientific literature on synbiotics includes a wide range of studies carried out under different conditions. Recent human trials have…

GMFH Editing Team
GMFH Editing Team

Human milk contains nutrients, bioactive compounds and commensal bacteria that may improve maternal and infant health outcomes. Milk’s microbial composition varies greatly between women but the factors that might explain this variation remain unknown. A new longitudinal cohort investigation, led by Dr. Carolina de Weerth from Radboud University Medical Center in the Netherlands, has found for the first time associations…

GMFH Editing Team
GMFH Editing Team

Human milk contains nutrients, bioactive compounds and commensal bacteria that may improve maternal and infant health outcomes. Milk’s microbial composition varies greatly between women but the factors that might explain this variation remain unknown. A new longitudinal cohort investigation, led by Dr. Carolina de Weerth from Radboud University Medical Center in the Netherlands, has found for the first time associations…

GMFH Editing Team
GMFH Editing Team

This post has been written by Dr. Numan Oezguen and Dr. James Versalovic. Previous research has shown that differences in the gut microbiomes of adult patients with irritable bowel syndrome (IBS) -both in structure and in the levels of metabolites produced or modified by gut microbes- often accompany abdominal pain. An association between gastrointestinal microbes and IBS in children has…

GMFH Editing Team
GMFH Editing Team

This post has been written by Dr. Numan Oezguen and Dr. James Versalovic. Previous research has shown that differences in the gut microbiomes of adult patients with irritable bowel syndrome (IBS) -both in structure and in the levels of metabolites produced or modified by gut microbes- often accompany abdominal pain. An association between gastrointestinal microbes and IBS in children has…

GMFH Editing Team
GMFH Editing Team

Poor sleep quality is a widespread problem and has been associated with several diseases in humans such as cardiovascular disease and cancer. Previous research has reported that the human gut microbiota may express endogenous circadian rhythms, together with findings showing alterations of the gut microbiota in response to sleep deprivation. On the other hand, the gut microbiota and its metabolites…

Allison Clark
Allison Clark has a master in nutrition and health from Open University in Barcelona and a master in journalism. She is a freelance writer and nutritionist and has written various peer review papers about the role the gut microbiota plays in health, disease and endurance exercise performance. Allison is passionate about the role diet and the gut microbiota play in health and disease. Follow her on Twitter @Heal_your_Gut

Poor sleep quality is a widespread problem and has been associated with several diseases in humans such as cardiovascular disease and cancer. Previous research has reported that the human gut microbiota may express endogenous circadian rhythms, together with findings showing alterations of the gut microbiota in response to sleep deprivation. On the other hand, the gut microbiota and its metabolites…

Allison Clark
Allison Clark has a master in nutrition and health from Open University in Barcelona and a master in journalism. She is a freelance writer and nutritionist and has written various peer review papers about the role the gut microbiota plays in health, disease and endurance exercise performance. Allison is passionate about the role diet and the gut microbiota play in health and disease. Follow her on Twitter @Heal_your_Gut

The community of microorganisms residing in our gut have been shown to affect brain function and behavior. However, scientists still struggle to explain how gut-brain communication occurs. Chu and colleagues have unraveled mechanisms by which gut microbiota affects mice adaptation to fear conditioning. By using a classic Pavlovian test, the authors first trained mice to associate a tone with pain…

GMFH Editing Team
GMFH Editing Team

The community of microorganisms residing in our gut have been shown to affect brain function and behavior. However, scientists still struggle to explain how gut-brain communication occurs. Chu and colleagues have unraveled mechanisms by which gut microbiota affects mice adaptation to fear conditioning. By using a classic Pavlovian test, the authors first trained mice to associate a tone with pain…

GMFH Editing Team
GMFH Editing Team

Non-alcoholic fatty liver disease (NAFLD) is the main cause of chronic liver disease in developed countries. NAFLD often shares symptoms with other metabolic disorders such as type 2 diabetes and obesity. Recently, our gut microbiota has been revealed as a contributor to fatty liver disease development in both rodent models and NAFLD patients. However, the question of whether gut microbes…

GMFH Editing Team
GMFH Editing Team

Non-alcoholic fatty liver disease (NAFLD) is the main cause of chronic liver disease in developed countries. NAFLD often shares symptoms with other metabolic disorders such as type 2 diabetes and obesity. Recently, our gut microbiota has been revealed as a contributor to fatty liver disease development in both rodent models and NAFLD patients. However, the question of whether gut microbes…

GMFH Editing Team
GMFH Editing Team