Fernando Aspiroz

Written by Fernando Aspiroz

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"The human microbiota is a fundamental component of what it means to be human," says David Relman in a recent JAMA opinion piece. In this article, Relman gives a picture of the importance of the human microbiota in health and a brief history of how scientists have measured it. Relman names body site as one of the strongest determinants of…

Fernando Aspiroz

"The human microbiota is a fundamental component of what it means to be human," says David Relman in a recent JAMA opinion piece. In this article, Relman gives a picture of the importance of the human microbiota in health and a brief history of how scientists have measured it. Relman names body site as one of the strongest determinants of…

Fernando Aspiroz

The Third International Congress of Translational Research in Human Nutrition (ICTRHN) took place in Clermont-Ferrand, France, on June 26 & 27, 2015. This post is an overview of the final ICTRHN symposium on clinical implications. (See here and here for the rest of the GMFH coverage of ICTRHN.) Prof. Karine Clément, Institute of Cardiometabolism and Nutrition, France -- Microbiota in…

Fernando Aspiroz

The Third International Congress of Translational Research in Human Nutrition (ICTRHN) took place in Clermont-Ferrand, France, on June 26 & 27, 2015. This post is an overview of the final ICTRHN symposium on clinical implications. (See here and here for the rest of the GMFH coverage of ICTRHN.) Prof. Karine Clément, Institute of Cardiometabolism and Nutrition, France -- Microbiota in…

Fernando Aspiroz

At the second PreProSim -- Brazilian Congress on Pre, Pro and Synbiotics --, several sessions on June 16th covered the topic of metabolic disorders and obesity. Koen Venema, Top Institute Food & Nutrition [TIFN], the Netherlands - Prebiotics and probiotics in metabolic syndrome Koen Venema says transplant studies show the microbiota can induce obesity. He introduced a review on the topic…

Fernando Aspiroz

At the second PreProSim -- Brazilian Congress on Pre, Pro and Synbiotics --, several sessions on June 16th covered the topic of metabolic disorders and obesity. Koen Venema, Top Institute Food & Nutrition [TIFN], the Netherlands - Prebiotics and probiotics in metabolic syndrome Koen Venema says transplant studies show the microbiota can induce obesity. He introduced a review on the topic…

Fernando Aspiroz

Topics at the IHMC 2015 meeting in Luxembourg were wide-ranging. Here are some highlights of particular interest: Sven Pettersson, Karolinska Institute, on MICROBE COMPARTMENTALIZATION Pettersson talked about possible compartmentalization of microbe-host interactions. He noted that keeping microbes within the boundaries in which they are compartmentalized is an energy-saving process. The stressed immune system consumes energy, and if the microbiome is involved in…

Fernando Aspiroz

Topics at the IHMC 2015 meeting in Luxembourg were wide-ranging. Here are some highlights of particular interest: Sven Pettersson, Karolinska Institute, on MICROBE COMPARTMENTALIZATION Pettersson talked about possible compartmentalization of microbe-host interactions. He noted that keeping microbes within the boundaries in which they are compartmentalized is an energy-saving process. The stressed immune system consumes energy, and if the microbiome is involved in…

Fernando Aspiroz

This is an update, on a rainy March 31, 2015, live from the 5th Congress of the International Human Microbiome Consortium, held in LuxExpo, Luxembourg. Here we are again, after the Hangzhou meeting 18 months ago, in Europe this time. We are all expecting another nice meeting and indeed the plenary sessions of the afternoon did set the pace nicely. Joe…

Fernando Aspiroz

This is an update, on a rainy March 31, 2015, live from the 5th Congress of the International Human Microbiome Consortium, held in LuxExpo, Luxembourg. Here we are again, after the Hangzhou meeting 18 months ago, in Europe this time. We are all expecting another nice meeting and indeed the plenary sessions of the afternoon did set the pace nicely. Joe…

Fernando Aspiroz

Gnotobiotic animals have long been used to highlight major functions of the intestinal microbiota such as its contribution to trophic development of gut tissues, immune maturation, direct protection from colonization/proliferation of pathogens (the barrier effect) and more recently its implication in metabolism and fat storage. Yet gnotobiology had never been used in a systematic way as a screening tool. This…

Fernando Aspiroz

Gnotobiotic animals have long been used to highlight major functions of the intestinal microbiota such as its contribution to trophic development of gut tissues, immune maturation, direct protection from colonization/proliferation of pathogens (the barrier effect) and more recently its implication in metabolism and fat storage. Yet gnotobiology had never been used in a systematic way as a screening tool. This…

Fernando Aspiroz

The intestinal microbiota is known to modulate bioavailability and efficacy of endogenous compounds, nutrients or drugs, with large interindividual variations. The least conserved fraction of our microbiota may hence explain a stratification of the human population in converters and non converters for numerous compounds. As an example, the reduction of cholesterol to coprostanol is only active in a fraction of…

Fernando Aspiroz

The intestinal microbiota is known to modulate bioavailability and efficacy of endogenous compounds, nutrients or drugs, with large interindividual variations. The least conserved fraction of our microbiota may hence explain a stratification of the human population in converters and non converters for numerous compounds. As an example, the reduction of cholesterol to coprostanol is only active in a fraction of…

Fernando Aspiroz