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GMFH Editing Team

A major focus of gut microbiome research in early life is how delivery mode affects the newborn gut microbiota and its impact on the health of the growing child. Although previous studies revealed that infants born by Caesarean section (C-section) develop a gut microbiota composition that more closely resembles adult skin and the hospital environment, and which may predispose newborns…

GMFH Editing Team
GMFH Editing Team

A major focus of gut microbiome research in early life is how delivery mode affects the newborn gut microbiota and its impact on the health of the growing child. Although previous studies revealed that infants born by Caesarean section (C-section) develop a gut microbiota composition that more closely resembles adult skin and the hospital environment, and which may predispose newborns…

GMFH Editing Team
GMFH Editing Team

A lack of sun exposure/UVB radiation has been linked to a decrease in vitamin D synthesis, which has been hypothesized to be one of the environmental factors related to the current rise in immune-related conditions through involving the gut microbiota. However, mouse and small human observational studies that showed associations between vitamin D and the gut microbiome do not allow…

GMFH Editing Team
GMFH Editing Team

A lack of sun exposure/UVB radiation has been linked to a decrease in vitamin D synthesis, which has been hypothesized to be one of the environmental factors related to the current rise in immune-related conditions through involving the gut microbiota. However, mouse and small human observational studies that showed associations between vitamin D and the gut microbiome do not allow…

GMFH Editing Team
GMFH Editing Team

Recurrent abdominal pain, which refers to functional abdominal pain disorders under the Rome IV classification, is a common problem affecting up to 25% of school-age children. As an organic cause is missing with this condition, parents of children affected by functional abdominal pain consider diet and behavioral therapies as methods of managing recurring problems. Although the treatment of functional abdominal…

GMFH Editing Team
GMFH Editing Team

Recurrent abdominal pain, which refers to functional abdominal pain disorders under the Rome IV classification, is a common problem affecting up to 25% of school-age children. As an organic cause is missing with this condition, parents of children affected by functional abdominal pain consider diet and behavioral therapies as methods of managing recurring problems. Although the treatment of functional abdominal…

GMFH Editing Team
GMFH Editing Team

Synbiotics are substances that combine a probiotic and prebiotic. While Gibson and Roberfroid were the first to anticipate that the two could be combined as synbiotics back in 1995, research in the field has accelerated over the past decade. The reported scientific literature on synbiotics includes a wide range of studies carried out under different conditions. Recent human trials have…

GMFH Editing Team
GMFH Editing Team

Synbiotics are substances that combine a probiotic and prebiotic. While Gibson and Roberfroid were the first to anticipate that the two could be combined as synbiotics back in 1995, research in the field has accelerated over the past decade. The reported scientific literature on synbiotics includes a wide range of studies carried out under different conditions. Recent human trials have…

GMFH Editing Team
GMFH Editing Team

Human milk contains nutrients, bioactive compounds and commensal bacteria that may improve maternal and infant health outcomes. Milk’s microbial composition varies greatly between women but the factors that might explain this variation remain unknown. A new longitudinal cohort investigation, led by Dr. Carolina de Weerth from Radboud University Medical Center in the Netherlands, has found for the first time associations…

GMFH Editing Team
GMFH Editing Team

Human milk contains nutrients, bioactive compounds and commensal bacteria that may improve maternal and infant health outcomes. Milk’s microbial composition varies greatly between women but the factors that might explain this variation remain unknown. A new longitudinal cohort investigation, led by Dr. Carolina de Weerth from Radboud University Medical Center in the Netherlands, has found for the first time associations…

GMFH Editing Team
GMFH Editing Team

This post has been written by Dr. Numan Oezguen and Dr. James Versalovic. Previous research has shown that differences in the gut microbiomes of adult patients with irritable bowel syndrome (IBS) -both in structure and in the levels of metabolites produced or modified by gut microbes- often accompany abdominal pain. An association between gastrointestinal microbes and IBS in children has…

GMFH Editing Team
GMFH Editing Team

This post has been written by Dr. Numan Oezguen and Dr. James Versalovic. Previous research has shown that differences in the gut microbiomes of adult patients with irritable bowel syndrome (IBS) -both in structure and in the levels of metabolites produced or modified by gut microbes- often accompany abdominal pain. An association between gastrointestinal microbes and IBS in children has…

GMFH Editing Team
GMFH Editing Team

The community of microorganisms residing in our gut have been shown to affect brain function and behavior. However, scientists still struggle to explain how gut-brain communication occurs. Chu and colleagues have unraveled mechanisms by which gut microbiota affects mice adaptation to fear conditioning. By using a classic Pavlovian test, the authors first trained mice to associate a tone with pain…

GMFH Editing Team
GMFH Editing Team

The community of microorganisms residing in our gut have been shown to affect brain function and behavior. However, scientists still struggle to explain how gut-brain communication occurs. Chu and colleagues have unraveled mechanisms by which gut microbiota affects mice adaptation to fear conditioning. By using a classic Pavlovian test, the authors first trained mice to associate a tone with pain…

GMFH Editing Team
GMFH Editing Team

Non-alcoholic fatty liver disease (NAFLD) is the main cause of chronic liver disease in developed countries. NAFLD often shares symptoms with other metabolic disorders such as type 2 diabetes and obesity. Recently, our gut microbiota has been revealed as a contributor to fatty liver disease development in both rodent models and NAFLD patients. However, the question of whether gut microbes…

GMFH Editing Team
GMFH Editing Team

Non-alcoholic fatty liver disease (NAFLD) is the main cause of chronic liver disease in developed countries. NAFLD often shares symptoms with other metabolic disorders such as type 2 diabetes and obesity. Recently, our gut microbiota has been revealed as a contributor to fatty liver disease development in both rodent models and NAFLD patients. However, the question of whether gut microbes…

GMFH Editing Team
GMFH Editing Team

Obesity and type 2 diabetes (T2D) have been associated with alterations in the gut microbiome. Given that both conditions are commonly manifested together and that ruling out the impact of external confounding factors in microbiome variation is a challenge, scientists struggle with teasing out gut microbiome hallmarks that uniquely characterize each of the two conditions. Louise Thingholm from Kiel University…

GMFH Editing Team
GMFH Editing Team

Obesity and type 2 diabetes (T2D) have been associated with alterations in the gut microbiome. Given that both conditions are commonly manifested together and that ruling out the impact of external confounding factors in microbiome variation is a challenge, scientists struggle with teasing out gut microbiome hallmarks that uniquely characterize each of the two conditions. Louise Thingholm from Kiel University…

GMFH Editing Team
GMFH Editing Team

Opting to follow a vegetarian diet is becoming a growing trend in Western countries, but is it a healthy choice as well? What impact does a plant-based diet have on the gut microbiota compared with an omnivorous one? Suzanne Devkota, PhD, Assistant Professor in the Gastroenterology division at Cedars Sinai Medical Centre (USA), is interested about the convergence of food, health…

GMFH Editing Team
GMFH Editing Team

Opting to follow a vegetarian diet is becoming a growing trend in Western countries, but is it a healthy choice as well? What impact does a plant-based diet have on the gut microbiota compared with an omnivorous one? Suzanne Devkota, PhD, Assistant Professor in the Gastroenterology division at Cedars Sinai Medical Centre (USA), is interested about the convergence of food, health…

GMFH Editing Team
GMFH Editing Team