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Written by GMFH Editing Team

GMFH Editing Team

Emerging evidence shows the involvement of our gut microbiome in conditions apparently unrelated to the gut ecosystem. And it seems that is the case with polycystic ovary syndrome (PCOS), which is a heterogeneous endocrine disorder that is often accompanied by altered insulin activity. Recent studies have associated alterations in gut microbiome composition and barrier function with imbalances in the stool…

GMFH Editing Team
GMFH Editing Team

Emerging evidence shows the involvement of our gut microbiome in conditions apparently unrelated to the gut ecosystem. And it seems that is the case with polycystic ovary syndrome (PCOS), which is a heterogeneous endocrine disorder that is often accompanied by altered insulin activity. Recent studies have associated alterations in gut microbiome composition and barrier function with imbalances in the stool…

GMFH Editing Team
GMFH Editing Team

The source of variation in the composition and function of the microbiome within and between species is yet to be fully understood. Although genetic background and diet have been suggested as major drivers of gut microbiome composition, the role of genetics versus environmental factors in driving gut microbiome variation in closely related primates remains unclear. A new study by Dr.…

GMFH Editing Team
GMFH Editing Team

The source of variation in the composition and function of the microbiome within and between species is yet to be fully understood. Although genetic background and diet have been suggested as major drivers of gut microbiome composition, the role of genetics versus environmental factors in driving gut microbiome variation in closely related primates remains unclear. A new study by Dr.…

GMFH Editing Team
GMFH Editing Team

Traditionally, microbial communities that inhabit the human body and surrounding environments have been characterized through culturing on selective plates. However, this approach shows a low sensitivity and does not allow for exploring the unculturable fraction of the microbiome that may account for between 60% and 80% of the observable bacteria. Although culture-independent methods based on characterizing the 16S ribosomal ribonucleic…

GMFH Editing Team
GMFH Editing Team

Traditionally, microbial communities that inhabit the human body and surrounding environments have been characterized through culturing on selective plates. However, this approach shows a low sensitivity and does not allow for exploring the unculturable fraction of the microbiome that may account for between 60% and 80% of the observable bacteria. Although culture-independent methods based on characterizing the 16S ribosomal ribonucleic…

GMFH Editing Team
GMFH Editing Team

Parkinson’s disease is caused by the progressive loss of dopaminergic neurons and recent studies have widened the immune system and the gut microbiota's contribution to the disease. A new study in mice, led by researchers from the Université de Montréal and McGill University in Canada, shows the involvement of intestinal infections as a trigger in Parkinson’s disease through autoimmune mechanisms.…

GMFH Editing Team
GMFH Editing Team

Parkinson’s disease is caused by the progressive loss of dopaminergic neurons and recent studies have widened the immune system and the gut microbiota's contribution to the disease. A new study in mice, led by researchers from the Université de Montréal and McGill University in Canada, shows the involvement of intestinal infections as a trigger in Parkinson’s disease through autoimmune mechanisms.…

GMFH Editing Team
GMFH Editing Team

The fact some people respond to a drug treatment while for others the same treatment is totally ineffective may depend on our gut microbiota. In other words, after a drug is administered orally, it could either be absorbed into the bloodstream and metabolized by the liver, or it remains in the intestine where it can be metabolized by the gut…

GMFH Editing Team
GMFH Editing Team

The fact some people respond to a drug treatment while for others the same treatment is totally ineffective may depend on our gut microbiota. In other words, after a drug is administered orally, it could either be absorbed into the bloodstream and metabolized by the liver, or it remains in the intestine where it can be metabolized by the gut…

GMFH Editing Team
GMFH Editing Team

In Canada, 3,500 kids and their families are part of the CHILD Cohort Study, which is a large research project that is figuring out how the human microbiome influences allergies, asthma, obesity, and our everyday health and wellbeing, especially during childhood. Find out in the next video, produced by AllerGen NCE Inc., how the gut microbiota can be altered by many…

GMFH Editing Team
GMFH Editing Team

In Canada, 3,500 kids and their families are part of the CHILD Cohort Study, which is a large research project that is figuring out how the human microbiome influences allergies, asthma, obesity, and our everyday health and wellbeing, especially during childhood. Find out in the next video, produced by AllerGen NCE Inc., how the gut microbiota can be altered by many…

GMFH Editing Team
GMFH Editing Team

Imbalances in the small intestinal microbiome can drive clinical consequences in the form of small intestinal bacterial overgrowth (SIBO), characterized by higher numbers of bacteria and a distribution more commonly associated with the colon. In recent times, SIBO has been recognized as a frequent cause of common gastrointestinal conditions that share risk factors such as maldigestion and malabsorption. Methods used…

GMFH Editing Team
GMFH Editing Team

Imbalances in the small intestinal microbiome can drive clinical consequences in the form of small intestinal bacterial overgrowth (SIBO), characterized by higher numbers of bacteria and a distribution more commonly associated with the colon. In recent times, SIBO has been recognized as a frequent cause of common gastrointestinal conditions that share risk factors such as maldigestion and malabsorption. Methods used…

GMFH Editing Team
GMFH Editing Team

Maternal physiology and metabolism during pregnancy adjust so the fetus may grow healthy. As part of these changes, the gut microbiota evolves towards a pro-inflammatory profile, which contributes to a healthy pregnancy. Even so, the extent to which gut microbiota alterations induced by pregnancy and lactation may change autoimmune mechanisms that are involved in disease has not yet been explored.…

GMFH Editing Team
GMFH Editing Team

Maternal physiology and metabolism during pregnancy adjust so the fetus may grow healthy. As part of these changes, the gut microbiota evolves towards a pro-inflammatory profile, which contributes to a healthy pregnancy. Even so, the extent to which gut microbiota alterations induced by pregnancy and lactation may change autoimmune mechanisms that are involved in disease has not yet been explored.…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

Preterm infants are at a high risk of growth failure that may affect their long-term health outcomes. Different factors have been involved in the etiology of postnatal growth failure in preterm infants, but despite research efforts regarding clinical management, growth failure rates continue to increase. Although differences in gut microbiota composition have been found in preterm infants compared with full-term…

GMFH Editing Team
GMFH Editing Team

Preterm infants are at a high risk of growth failure that may affect their long-term health outcomes. Different factors have been involved in the etiology of postnatal growth failure in preterm infants, but despite research efforts regarding clinical management, growth failure rates continue to increase. Although differences in gut microbiota composition have been found in preterm infants compared with full-term…

GMFH Editing Team
GMFH Editing Team