Scientists have discovered a fungus that delays wound healing in mice and is enriched in inflamed tissue from patients with Crohn’s disease. The findings, coupled with the discovery of an engineered yeast that suppresses inflammation in a mouse model of colitis, highlights the potential of studying fungi-host interactions in IBD.

The role of gut microbiota in shaping immune responses has led scientists to explore the modulation of the immune system as a mechanism underlying the health benefits of probiotics. A new systematic review and meta-analysis of 9 randomized clinical trials suggest probiotics may reduce the incidence of respiratory and gastrointestinal tract infections in generally healthy children and adults.

Although the COVID-19 pandemic has shifted the focus of research for scientists worldwide, major breakthroughs in gut microbiome science have been made in 2020. In this last post of the year, we bring you articles from our blog that cover the major advances in the gut microbiome in 2020, from bench to bedside.