Prebiotics have been widely researched in the context of gastrointestinal conditions and might hold potential to influence cognition outcomes by modulating the microbiota-gut-brain axis. A new randomised controlled trial in individuals aged over 60s showed that a prebiotic blend (inulin and fructo-oligosaccharides) is well tolerated and may improve cognition compared with a placebo.

Carbohydrate malabsorption is an underlying cause of irritable bowel syndrome-type symptoms in some patients. This article explores the impact of fermentable short-chain carbohydrates (FODMAPs) on gut function, the benefits and risks of a low-FODMAP diet, and how probiotics can help individuals with carbohydrate malabsorption.

Non-prescription therapeutics for IBS: where are we?

30 Jan 2024

by Andrea Costantino

Alterations in the gut microbiome composition and functions are emerging as a potential target for managing IBS. Discover how microbiota-modifying treatments, including prebiotics, probiotics, antibiotics, and fecal microbiota transplantation, hold promise in alleviating symptoms of this vexing condition.

Dietary fibers, known to regulate intestinal inflammation and gut barrier functions, have been avoided by patients with inflammatory bowel diseases (IBD) to avoid flare-ups. However, recent findings suggest that if fiber type, patient immunological condition, and the fermentative ability of the gut microbiota are taken into account, they could be beneficial and prevent relapses.

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