Inflammation has been involved in the onset of chronic diseases. Probiotics emerge as a potential dietary tool for managing those conditions, partly through their role in immune system modulation and the anti-inflammatory response. Find out what is known about the anti-inflammatory effects of probiotics and their potential applications at the bedside.

Fecal microbiota transplantation is being studied in the context of metabolic health, beyond its use for recurrent Clostridioides difficile infection. A new proof-of-principle study reveals that supplementing low-fermentable fiber following fecal microbiota transplantation may improve insulin sensitivity in individuals with severe obesity.

Despite the fact that current guidelines for managing inflammatory bowel diseases do not devote attention to diet as a central element of treatment, there is an increasing amount of evidence that supports the role of diet in patients with IBD. A new nationwide cohort study shows the association between the level of inflammatory potential in diet and risk of Crohn’s disease.

Gut microbiota alterations in obesity remain the subject of debate. Writing in Nature, Vieira-Silva and colleagues found that the undesirable Bacteroides 2 enterotype was more frequent in people with a higher body mass index, but not if they were taking statins.

Gut microbiota, with its close links to metabolism and the immune system, could potentially be a factor that lies at the core of good health. This means it can be positioned at the heart of the processes that influence the risk of contracting different diseases.