At the Gut Microbiota for Health World Summit 2016 that was held in Miami (USA) March 5-6, 2016, leading experts presented up-to-date evidence on clinical applications of gut microbiota and its mechanisms and role in human health and disease.

Researchers know the fecal microbiota of infants is a treasure trove of information -- it can reveal details about delivery mode and diet -- but microbiota-based predictions about future health are only beginning to emerge. A team of researchers led

"The human microbiota is a fundamental component of what it means to be human," says David Relman in a recent JAMA opinion piece. In this article, Relman gives a picture of the importance of the human microbiota in health and a brief history of how scientists have measured it.

This Chinese study aimed to characterize the gut microbiota of patients with major depressive disorder (MDD): one group of patients with acute MDD (who scored high on a depression scale, indicating clinically significant depression), called 'active-MDD', and a second group of patients with a history of MDD who had responded to treatment (achieving a 50% reduction in depression scale scores after 4 weeks of treatment), called 'responded-MDD'.

Bifidobacteria colonization in newborns

5 Aug 2015

by GMFH Editing Team

Bifidobacteria is a key marker of a healthy gut flora in infants. A Brazilian study of 49 newborns -- 24 full-term and 25 pre-term (31.2 weeks) -- explored the prevalence and concentration of bifidobacteria in stools of one-month-old newborns using qPCR.

Previous research has shown that adults with irritable bowel syndrome (IBS) who adopt a low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet show an improvement in symptoms within 2 days. Would the low FODMAP diet have the same effect in childhood IBS? Does the gut microbiota predict the success of the diet in children who respond to this dietary intervention?

Faecalibacterium prausnitzii is known for exhibiting anti-inflammatory effects in vitro and in vivo by secreted metabolites that block nuclear factor (NF)-κB activation. The low proportion of F. prausnitzii in the microbiome of Crohn’s disease patients characterizes the microbial dysbiosis associated with that condition.