by GMFH Editing Team
Gut microbiome-targeted interventions are being explored as means of improving cognitive performance. A new meta-analysis of 22 randomized controlled studies has found no significant effect on improving cognition for probiotics, prebiotics and fermented foods, whether alone or used in combination.
by GMFH Editing Team
Host lifestyle and diet are known to have a significant impact on the gut microbiome. A large observational study across 3400 individuals shows that, beyond interindividual variability, gut microbiome heterogeneity may play a role in individual responses to diet, lifestyle and medication.
by GMFH Editing Team
How the enteric nervous system interacts with surrounding host and microbial cells is largely unknown, mainly due to the limitations of available methodologies for studying enteric neurons. A recent study provides new insights into enteric nervous system cells from both the mouse and human intestine.
by Rene van den Wijngaard
Despite the fact that current guidelines for managing inflammatory bowel diseases do not devote attention to diet as a central element of treatment, there is an increasing amount of evidence that supports the role of diet in patients with IBD. A new nationwide cohort study shows the association between the level of inflammatory potential in diet and risk of Crohn’s disease.
by Heather Galipeau
Evidence over the past few years suggests that metabolites produced from microbes in the gut play a crucial role in maintaining gut health.
by Patrice D. Cani
Enteric neurons have recently emerged as a new target in the management of type 2 diabetes. The findings in mice and humans identify new intestinal bioactive compounds released after prebiotic administration, with potential for improving glucose metabolism.
by Andreu Prados
The microbiota of infants born by caesarean section resembles that of maternal oral cavity and skin, whereas that of vaginally born infants resembles that of the maternal gut microbiome. A new proof-of-concept study shows that the gut microbiota of C-section-born infants can be restored after delivery via orally administered maternal fecal microbiota transplantation.
by GMFH Editing Team
The heterogeneity of cross-sectional IBS studies has limited elucidating the gut ecosystem’s overall involvement in the disease pathogenesis. New longitudinal research that integrates multi-omics, patient and gastrointestinal data reveals previously unidentified targets that accompany changes in IBS activity.
by Andreu Prados
An altered balance of the community of microbes that reside in our body, especially within the gut, has been linked to a wide range of intestinal and extraintestinal diseases. What evidence-based strategies are currently available for modulating the gut microbiota?
Irritable bowel syndrome is one of the most common disorders diagnosed by gastroenterologists. Peppermint oil, specific probiotics, psyllium supplementation, first-line IBS dietary advice, and a low FODMAP diet can aid in improving IBS symptoms.