Beyond live microorganisms, inanimate microorganisms and their components can also confer a health benefit on the host. A panel of experts under the auspices of the International Scientific Association for Probiotics and Prebiotics (ISAPP) updates the definition and scope of postbiotics.

Analysing the molecular and biochemical mechanisms disturbing the complex network of communication is key to our understanding of the pathophysiology of the functional GI disorders. Together with ESNM we have prepared an exciting webinar series under the topic: Microbiota and Gut-Brain Connection: A new Frontier in Neurogastroenterology. This free resource is a great opportunity to hear leading worldwide experts presenting the most recent findings on this topic.

The role of gut microbiota in shaping immune responses has led scientists to explore the modulation of the immune system as a mechanism underlying the health benefits of probiotics. A new systematic review and meta-analysis of 9 randomized clinical trials suggest probiotics may reduce the incidence of respiratory and gastrointestinal tract infections in generally healthy children and adults.

Beyond antibiotics, a wide range of commonly used non-antibiotic drugs can affect the gut microbiome. In addition, the gut microbiome can also influence an individual’s response to drugs by affecting their efficacy and safety. What are the implications of the bidirectional interaction between non-antibiotic drugs and the gut microbiome in the clinical setting?

Although the COVID-19 pandemic has shifted the focus of research for scientists worldwide, major breakthroughs in gut microbiome science have been made in 2020. In this last post of the year, we bring you articles from our blog that cover the major advances in the gut microbiome in 2020, from bench to bedside.