Archives des Chron

Targeting fungi for Crohn’s disease? A fungus used in the food industry for surface ripening cheese and meat is involved in impairing colonic healing

15 Sep 2021

by Andreu Prados

Scientists have discovered a fungus that delays wound healing in mice and is enriched in inflamed tissue from patients with Crohn’s disease. The findings, coupled with the discovery of an engineered yeast that suppresses inflammation in a mouse model of colitis, highlights the potential of studying fungi-host interactions in IBD.

The inflammatory potential of diet is tied to Crohn’s disease risk but not to ulcerative colitis, suggests a new observational study

2 Nov 2020

by Rene van den Wijngaard

Despite the fact that current guidelines for managing inflammatory bowel diseases do not devote attention to diet as a central element of treatment, there is an increasing amount of evidence that supports the role of diet in patients with IBD. A new nationwide cohort study shows the association between the level of inflammatory potential in diet and risk of Crohn’s disease.

Higher mucins production and an imbalanced gut microbiota found in Crohn´s Disease remission patients

26 Sep 2019

by Allison Clark

Scientists struggle to understand why some gut bacteria are sensitive to antibiotics while a fraction of them survive treatment. New research in mice reveals that gut microbial metabolism alongside diet play a key role in modifying the extent of gut microbiome disruption in response to antibiotics.

The ileal mucosa-associated microbiota may help predict recurrence in patients with Crohn’s disease

20 Jun 2019

by GMFH Editing Team

Clinicians struggle with finding a single risk marker for predicting early postoperative endoscopic recurrence in Crohn’s disease. Researchers from Saint Antoine Hospital and other institutions reveal that ileal mucosa-associated microbiota may help predict recurrence in patients with CD after ileocecal resection.

New research sheds light on the effects of inflammatory bowel disease risk alleles on gut bacterial taxa

8 Apr 2019

by GMFH Editing Team

Scientists struggle with elucidating how host and gut microbiome interact for shaping the genetic susceptibility of IBD. In 633 IBD patients, Harry Sokol and colleagues have found associations between genetic variants associated with a higher risk of IBD and the depletion of certain gut bacterial taxa.

The most significant achievements in gut microbiome science in 2018

27 Dec 2018

by GMFH Editing Team

GMFH continue to cover the important progress made in our knowledge of the gut microbiota's impact on wellbeing and disease.

New research supports the contribution of the gut microbiota in Crohn’s disease pathogenesis

13 Aug 2018

by Andreu Prados

The researchers studied the influence of genotypic and phenotypic factors on the gut microbiota and characterized the mucosal microbiota in 21 patients with quiescent Crohn’s disease (CD), 17 young healthy siblings of CD patients and 19 unrelated healthy controls.

The timing of food consumption influences the human salivary microbiota

22 Mar 2018

by Andreu Prados

A recent study has found that meal timing affects the daily rhythm of the human salivary microbiota and that timing differences may have a deleterious effect on the metabolism of the host.

Rome to host 7th edition of Gut Microbiota for Health World Summit

4 Dec 2017

by GMFH Editing Team

A scientific committee chaired has taken care to put together a program that covers the most relevant issues in the field today.

A new review explores how targeting gut bacteria and fungi interactions may help manage chronic intestinal inflammation

23 Nov 2017

by Andreu Prados

A recent review article explores the role of the interactions between bacteria and fungi in Crohn’s disease and potential strategies to target the gut microbiota in gastrointestinal diseases.