Scientists have discovered a fungus that delays wound healing in mice and is enriched in inflamed tissue from patients with Crohn’s disease. The findings, coupled with the discovery of an engineered yeast that suppresses inflammation in a mouse model of colitis, highlights the potential of studying fungi-host interactions in IBD.

Little is known about the relationship between diet, the composition and function of the gut microbiota and clinical symptoms of IBS. New findings identify how IBS symptom severity is related to a higher intake of foods with poor nutritional quality and gut microbiome features at both subspecies level and metabolic pathways involved in carbohydrate metabolism.

Analysing the molecular and biochemical mechanisms disturbing the complex network of communication is key to our understanding of the pathophysiology of the functional GI disorders. Together with ESNM we have prepared an exciting webinar series under the topic: Microbiota and Gut-Brain Connection: A new Frontier in Neurogastroenterology. This free resource is a great opportunity to hear leading worldwide experts presenting the most recent findings on this topic.

Although the COVID-19 pandemic has shifted the focus of research for scientists worldwide, major breakthroughs in gut microbiome science have been made in 2020. In this last post of the year, we bring you articles from our blog that cover the major advances in the gut microbiome in 2020, from bench to bedside.

Many studies have reported changes in gut microbiome composition in patients with inflammatory bowel disease, including ulcerative colitis, when compared with healthy individuals. While that clearly raises the question about the key role played by gut microbes in IBD pathogenesis, we have yet to pinpoint the causative microbes and their mechanisms.

Does glyphosate affect the gut microbiome?

7 Dec 2020

by Andreu Prados

Gluten is not the only culprit in unwanted intestinal and extra-intestinal symptoms among non-celiac individuals. Recently, the herbicide glyphosate, present in residual amounts in foods, has received a lot of attention when it comes to digestive and overall health.