The human gut microbiome is packed with enzymes that can transform food, drugs, or pollutants. New research maps interactions between dietary xenobiotics and the gut microbiome, explaining why diet can work differently for different people.
The link between environmental and microbial factors and Crohn’s disease risk
29 Jul 2024by Rene van den Wijngaard
Whether environmental and microbial factors are the cause or consequence of Crohn’s disease is still subject to debate. Two recent studies by the Crohn’s and Colitis Canada—Genetic, Environmental, Microbial project have identified new clues.
Gut fungi have effects beyond the gut through the gut-brain axis
14 Feb 2024by Rene van den Wijngaard, Andreu Prados
Most research on the role of gut microbiota in the gut-brain axis has focused on bacteria, while fungi living inside the gut have been overlooked. What do we know about the role of gut fungi in the communication between the gut and the brain?
Where are we on microbiome-based therapies in disorders of gut-brain interaction?
4 Dec 2023by Andreu Prados, Rene van den Wijngaard
NeuroGASTRO 2023, the leading meeting in Europe held by ESNM on the latest developments in neurogastroenterology, digestive motility, and disorders of gut-brain interaction, took place from August 31st to September 2nd, 2023. Find out more about the main takeaways from the role of fecal microbiota transplants, microbial consortia and probiotics in disorders of gut-brain interaction picked up by GMFH editors (Part 2).
Research highlights from NeuroGASTRO 2023: food, mast cells, eosinophils and gut barrier in disorders of gut-brain interaction
6 Nov 2023by Andreu Prados, Rene van den Wijngaard
NeuroGASTRO 2023, the leading meeting in Europe held by ESNM on the latest developments in neurogastroenterology, digestive motility, and disorders of the gut-brain interaction, took place from August 31st to September 2nd, 2023. Find out more what the latest research says about the involvement of the intestinal microbiota, mast cells, eosinophils and gut barrier in disorders of gut-brain interaction and dietary considerations in their management picked up by GMFH editors (Part 1).
Keystone Bacteroides strain restitution leads to microbiome recovery and reduced risk of colitis in genetically susceptible mice
29 Mar 2022by Rene van den Wijngaard
Alterations in the gut microbiome in early life have been associated with increased risk of inflammatory bowel diseases. New findings in mice have found a keystone Bacteroides strain that reduces colitis risk when engrafted during early life in a gut microbiome disrupted by antibiotics.
2021 at a glance: hotspots in gut microbiome research and predictions for the field’s future development
10 Jan 2022by GMFH Editing Team, Rene van den Wijngaard
Despite the global focus on COVID-19, 2021 was also a productive year in gut microbiome research. In this “2021 Year at a glance” report, discover emerging trends in postbiotics, the role of beneficial microbes in dietary guidelines, diet-related tools for shaping the gut microbiome and the potential role of newly identified probiotics in obesity and functional dyspepsia.
Spore-forming probiotic blend shows potential for managing functional dyspepsia in adults
11 Oct 2021by Rene van den Wijngaard
Long-term treatment of functional dyspepsia with proton-pump inhibitors can alter the gut microbiome. A new pilot randomized, double-blind, placebo-controlled trial suggests the potential of spore-forming probiotics in patients with functional dyspepsia.
Does functional abdominal pain have an organic explanation? Gut-localized immune responses offer new clues for patients with functional gastrointestinal disorders
8 Mar 2021by Rene van den Wijngaard
Abdominal pain affects a huge amount of people nowadays, though its underlying mechanisms are not always understood. New findings in mice and humans reveal that localized immune responses against harmless foods might be involved in persistent “functional” abdominal pain.
The inflammatory potential of diet is tied to Crohn’s disease risk but not to ulcerative colitis, suggests a new observational study
2 Nov 2020by Rene van den Wijngaard
Despite the fact that current guidelines for managing inflammatory bowel diseases do not devote attention to diet as a central element of treatment, there is an increasing amount of evidence that supports the role of diet in patients with IBD. A new nationwide cohort study shows the association between the level of inflammatory potential in diet and risk of Crohn’s disease.
