About Mark Wulczynski

Dr. Mark Wulczynski is a postdoctoral fellow with the Farncombe Institute Nutrition Initiative at McMaster University, investigating how diet-host-microbe interactions affect gastrointestinal disorders such as celiac disease and inflammatory bowel diseases. Ultimately, Wulczynski envisions a personalized approach to the gluten-free diet, one where microbiome profiles or function help determine which fibres and other dietary approaches are most effective for each individual. He is now involved in clinical trials investigating microbiota in celiac disease and the immune response against gluten challenge.

Celiac disease is a chronic immune-mediated enteropathy that may be unleashed by enteric viral infections. However, new findings in mice identified a commensal protist, Tritrichomonas arnold, that protects against reovirus-induced intolerance to gluten by counteracting virus-induced proinflammatory dendritic cell activation.

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