Heather Galipeau, Author at Gut Microbiota for Health

About Heather Galipeau

Heather Galipeau is an Assistant Professor (part-time) and Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Study identifies a role for bacterial proteases in Crohn’s disease

26 Jun 2023

by Amber Hann, Heather Galipeau

Inflammatory bowel disease is a chronic remitting and relapsing condition that causes severe inflammation of the intestines and disabling bowel symptoms. It affects millions of lives globally, and although alterations in the gut microbiome have been associated with IBD, precise mechanisms remain incompletely understood. New research from McMaster University now implicates bacterial proteases in Crohn’s disease.

Small Intestinal Microbiome: An understudied ecosystem in celiac disease

8 Aug 2022

by Heather Galipeau

While celiac disease affects predominantly the small intestine, the contribution of the small intestinal microbiota has been largely understudied. New findings characterize the duodenal microbiota in patients with active celiac disease and explores its functional relevance.

Fecal bacterial protease activity may indicate progression to ulcerative colitis

14 Dec 2020

by Heather Galipeau

Many studies have reported changes in gut microbiome composition in patients with inflammatory bowel disease, including ulcerative colitis, when compared with healthy individuals. While that clearly raises the question about the key role played by gut microbes in IBD pathogenesis, we have yet to pinpoint the causative microbes and their mechanisms.

Gut microbes in celiac disease show impaired metabolism of dietary tryptophan, according to researchers at McMaster University

27 Oct 2020

by Heather Galipeau

Evidence over the past few years suggests that metabolites produced from microbes in the gut play a crucial role in maintaining gut health.

Advances in the understanding of how microbes promote food sensitivity

4 Apr 2019

by Heather Galipeau

Genetic predisposition alone cannot fully explain the current rise of food sensitivities, like celiac disease. Scientists have characterized the bacterial enzyme elastase involved in driving immune activation and worsening reactions to gluten in genetically susceptible hosts.

Microbiota plays key role in shaping intestinal barrier structure and permeability

31 Oct 2018

by Heather Galipeau

The effects of the microbiota on immunity and metabolism have been well characterized, but the basic understanding of how microbes influence the overall structure and function of the intestinal barrier is not well understood.

Microbial-dependent inflammation may predispose to pre-leukemic changes in mice

11 Oct 2018

by Heather Galipeau

According to a new study gut microbiota-dependent signals are critical contributors to a pre-leukemic state in mice that lack Tet2 expression.

In irritable bowel syndrome, probiotic bacteria show promise for improving mood

5 Jul 2017

by Heather Galipeau

A new study shows that a specific probiotic can help treat symptoms of depression in patients who suffer from irritable bowel syndrome (or IBS).

Virus may lead to celiac disease through disruption of intestinal immune homeostasis

10 Apr 2017

by Heather Galipeau

A new study published in Science by Bouziat and colleagues show that reovirus, which are mild or clinically silent viruses that infect humans frequently over the course of a lifetime, can break tolerance to dietary proteins and may constitute an environmental modifier for CeD development.

Heather Galipeau

27 Mar 2017

by Heather Galipeau

Canada Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during

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