by GMFH Editing Team
Ulcerative colitis is a chronic debilitating inflammatory bowel disease with no curative treatment currently available. INRAE scientists have developed a novel predictive model of disease progression in pediatric patients that integrates both gut microbiota and host inflammation data.
by Heather Galipeau
Many studies have reported changes in gut microbiome composition in patients with inflammatory bowel disease, including ulcerative colitis, when compared with healthy individuals. While that clearly raises the question about the key role played by gut microbes in IBD pathogenesis, we have yet to pinpoint the causative microbes and their mechanisms.
by Rene van den Wijngaard
Despite the fact that current guidelines for managing inflammatory bowel diseases do not devote attention to diet as a central element of treatment, there is an increasing amount of evidence that supports the role of diet in patients with IBD. A new nationwide cohort study shows the association between the level of inflammatory potential in diet and risk of Crohn’s disease.
by Andreu Prados
The researchers investigated the role of the gut microbiome in disease severity, progression and treatment response in 405 pediatric.
A recent randomised placebo-controlled trial, led by Prof. Thomas Borody from the Centre for Digestive Diseases in Sydney (Australia), has found that faecal microbiota transplantation induces clinical remission and endoscopic improvement in patients with active ulcerative colitis.
Fecal microbiota transplantation (FMT) for patients with ulcerative colitis (UC) has shown mixed clinical results (see recent trials here and here). In a new pilot study, published as open access, Faming Zhang and colleagues tested the safety and efficacy of a "step-up" FMT strategy in 15 steroid-dependent UC patients.
by Kristina Campbell
Dr. Paul Moayyedi, a gastroenterologist and researcher at McMaster University in Hamilton, Canada, was the first author of a study published earlier this year that investigated fecal microbiota transplantation (FMT) as a way to induce remission in patients with ulcerative colitis (UC). (See the study summary here.)
by Paul Enck
Amsterdam researchers recently published an investigation of fecal microbiota transplantation (FMT) for the treatment of ulcerative colitis (UC).
by Paul Enck
Moayyedi et al. from Canada recently published a paper entitled Fecal Microbiota Transplantation Induces Remission in Patients with Active Ulcerative Colitis in a Randomized, Controlled Trial.
The Inflammatory Bowel Diseases (IBDs), which include Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic relapsing and remitting inflammatory disorders of the gastrointestinal tract.
