Research into microbial extracellular vesicles has progressed significantly over several decades. Following up on the 1989 breakthrough that bacterial extracellular vesicles contain genetic information, and the recent ISAPP definition on postbiotics, current research suggests bacterial extracellular vesicles derived from probiotic bacteria may be the postbiotics of the future with potential health benefits.
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What is bifidobacteria’s role in establishing a healthy infant gut microbiome and immune system?
20 Jun 2022by Andreu Prados
The role of the infant gut microbiome in immunological development is largely mediated by bifidobacteria. This article updates what factors affect bifidobacteria colonization in the gut and why bifidobacteria are relevant for infants, and reveals the groups of infants that will benefit from supplementation with bifidobacterial.
Allergic children present different bacterial strains that promote inflammation
21 Apr 2022by Manon Oliero
Rural living, vaginal delivery, pet ownership, eating a wide variety of foods, low antibiotic use, and breast milk microbiota can prevent your children from developing a respiratory or food allergy. But what if differences in the gut microbiota could predict which children will grow out of their allergies?
The first 1,000 days of life: the prominence of bifidobacteria for infants’ gut microbiota development and later health outcomes
4 Mar 2022by Konstantina Zafeiropoulou
The first 2-3 years of life are crucial for shaping childhood health. Amid others, the importance of early-life gut microbiota in infant’s development and later human health has been long speculated. In particular, bifidobacteria are playing an essential role in infant’s gut microbiota and immune system maturation that supports its probiotic use in that age span.
Calorie restriction leads to weight loss but may promote pathogenic bacteria
27 Oct 2021by Allison Clark
Restrictive diets in terms of calories and nutrients are widespread among people. Although this type of diets could help with weight loss in the short term, their long-term effects on the gut microbiome and overall health remain unknown.
Fecal bacterial protease activity may indicate progression to ulcerative colitis
14 Dec 2020by Heather Galipeau
Many studies have reported changes in gut microbiome composition in patients with inflammatory bowel disease, including ulcerative colitis, when compared with healthy individuals. While that clearly raises the question about the key role played by gut microbes in IBD pathogenesis, we have yet to pinpoint the causative microbes and their mechanisms.
Stunted growth in children does not have a simple root cause: bacteria in the small intestine emerge as new driver
31 Aug 2020by GMFH Editing Team
Undernutrition still remains a major cause of death in children in some locations. A team led by Tahmeed Ahmed and Jeffrey I. Gordon have found a new driver for stunting: the bacteria that reside within the small intestine.
New research shows the keto diet, used to treat neurological and metabolic diseases, suppresses bifidobacteria and Th17 cells
15 Jun 2020by Andreu Prados
Could the keto diet’s therapeutic benefits be linked to changes in the gut microbiota? New work in mice and 17 men who are overweight or obese reveals ketone bodies exert suppression of bifidobacteria and intestinal pro-inflammatory Th17 cells.
Lactic acid bacteria in fermented foods can be transferred to the human gut
8 Jun 2020by GMFH Editing Team
Fermented foods are a known source of lactic acid bacteria. A high-throughput sequencing analysis of food and human metagenomes proves that fermented foods are a source of lactic acid bacteria for the gut microbiome, and that abundance is shaped by both age and lifestyle.
Analysis of the fetal intestine suggests limited bacterial colonization with potential immunological functions
27 Apr 2020by Andreu Prados
Whether bacterial colonization starts in utero is still a matter for scientific debate. The study of the fetal intestinal content collected from terminated pregnancies reveals some evidence for early bacterial colonization linked to distinct immune imprinting.
