Certainties and uncertainties of SIBO

26 Oct 2023

by Andreu Prados

While SIBO is not new, it has recently gained popularity on the internet and on social media as the result of a set of non-specific symptoms such as abdominal pain, bloating, and even chronic fatigue. In this post, we will discuss what SIBO is and what it is not, its roots, symptoms, diagnosis, and management.

Chronic abdominal pain, diarrhea, constipation, and bloating are common gastrointestinal symptoms. While a structural or an organic disease can be suspected because of the symptoms and is often easy to be diagnosed by endoscopy or imaging methods, sometimes gastrointestinal symptoms are not related to any alteration that may be seen through diagnostic techniques, and consequently have been classified under the umbrella of “disorders of gut-brain interaction”.

Dietary fibers, known to regulate intestinal inflammation and gut barrier functions, have been avoided by patients with inflammatory bowel diseases (IBD) to avoid flare-ups. However, recent findings suggest that if fiber type, patient immunological condition, and the fermentative ability of the gut microbiota are taken into account, they could be beneficial and prevent relapses.

It’s time to delve into the world of short-chain fatty acids (SCFAs) and the crucial role they play in maintaining digestive health to gain a deeper understanding of how they contribute to overall well-being.

While celiac disease affects predominantly the small intestine, the contribution of the small intestinal microbiota has been largely understudied. New findings characterize the duodenal microbiota in patients with active celiac disease and explores its functional relevance.

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