Differences in the gut microbiota in patients with IBD compared to healthy controls suggest that probiotics may be of help. This article takes an in-depth look into the rationale of using probiotics for IBD and summarizes the evidence from recent clinical guidelines for the use of probiotics in Crohn’s disease, ulcerative colitis and pouchitis.
Study identifies a role for bacterial proteases in Crohn’s disease
26 Jun 2023by Amber Hann, Heather Galipeau
Inflammatory bowel disease is a chronic remitting and relapsing condition that causes severe inflammation of the intestines and disabling bowel symptoms. It affects millions of lives globally, and although alterations in the gut microbiome have been associated with IBD, precise mechanisms remain incompletely understood. New research from McMaster University now implicates bacterial proteases in Crohn’s disease.
Which dietary components should be promoted, and which ones should be limited in inflammatory bowel disease?
19 May 2023by GMFH Editing Team
What to eat or not to eat as a means of reducing IBD symptoms is one of the main queries a patient might have following diagnosis. Although there is no simple answer and dietary changes are not a substitute for medical therapy, to help consider this question, we have prepared a new infographic on the dietary components to promote and limit in patients with IBD.
Targeting fungi for Crohn’s disease? A fungus used in the food industry for surface ripening cheese and meat is involved in impairing colonic healing
15 Sep 2021by Andreu Prados
Scientists have discovered a fungus that delays wound healing in mice and is enriched in inflamed tissue from patients with Crohn’s disease. The findings, coupled with the discovery of an engineered yeast that suppresses inflammation in a mouse model of colitis, highlights the potential of studying fungi-host interactions in IBD.
Higher mucins production and an imbalanced gut microbiota found in Crohn´s Disease remission patients
26 Sep 2019by Allison Clark
Scientists struggle to understand why some gut bacteria are sensitive to antibiotics while a fraction of them survive treatment. New research in mice reveals that gut microbial metabolism alongside diet play a key role in modifying the extent of gut microbiome disruption in response to antibiotics.
The ileal mucosa-associated microbiota may help predict recurrence in patients with Crohn’s disease
20 Jun 2019by GMFH Editing Team
Clinicians struggle with finding a single risk marker for predicting early postoperative endoscopic recurrence in Crohn’s disease. Researchers from Saint Antoine Hospital and other institutions reveal that ileal mucosa-associated microbiota may help predict recurrence in patients with CD after ileocecal resection.
New research supports the contribution of the gut microbiota in Crohn’s disease pathogenesis
13 Aug 2018by Andreu Prados
The researchers studied the influence of genotypic and phenotypic factors on the gut microbiota and characterized the mucosal microbiota in 21 patients with quiescent Crohn’s disease (CD), 17 young healthy siblings of CD patients and 19 unrelated healthy controls.
The timing of food consumption influences the human salivary microbiota
22 Mar 2018by Andreu Prados
A recent study has found that meal timing affects the daily rhythm of the human salivary microbiota and that timing differences may have a deleterious effect on the metabolism of the host.
A new study has confirmed that certain oral bacteria can travel to the intestine and alter the balance of the gut microbiota, leading to the development of chronic intestinal diseases.
Scientists discover a possible link between gut microbiota and autoimmune diseases
31 Jan 2018by Cristina Sáez
A new study performed on mice by researchers from Spain and Canada has found that gut bacteria may play a role in protecting us from inflammatory bowel diseases (IBD) and specifically ulcerative colitis.
