Digestive Health

News Watch

According to the World Health Organization (WHO) and the Food and Agriculture Organization of the United Nations (FAO), probiotics are live microorganisms that, when consumed or administered in adequate amounts, have beneficial effects on the body. Probiotics are also usually used for the prevention and management of digestive symptoms that may be related to changes or an imbalance in the…

GMFH Editing Team
GMFH Editing Team

According to the World Health Organization (WHO) and the Food and Agriculture Organization of the United Nations (FAO), probiotics are live microorganisms that, when consumed or administered in adequate amounts, have beneficial effects on the body. Probiotics are also usually used for the prevention and management of digestive symptoms that may be related to changes or an imbalance in the…

GMFH Editing Team
GMFH Editing Team

Functional disorders are those in which the parameters of analyses and tests are normal, even though people may be suffering from pain or other symptoms. According to what Prof. Magnus Simren, chairman of the United European Gastroenterology (UEG) Scientific Committee, tells us in this interview, this kind of disorder frequently affects the digestive system. This video discusses the relationship that…

GMFH Editing Team
GMFH Editing Team

Functional disorders are those in which the parameters of analyses and tests are normal, even though people may be suffering from pain or other symptoms. According to what Prof. Magnus Simren, chairman of the United European Gastroenterology (UEG) Scientific Committee, tells us in this interview, this kind of disorder frequently affects the digestive system. This video discusses the relationship that…

GMFH Editing Team
GMFH Editing Team

Abdominal gases are created in the intestine during digestion and, beyond the jokes that this subject usually generates, it is an absolutely normal physiological process. In some cases, however, abdominal gases can be a source of discomfort. This situation may now have a scientific explanation. A study by the Physiology and Pathophysiology of the Digestive Tract Group at Vall d’Hebron…

GMFH Editing Team
GMFH Editing Team

Abdominal gases are created in the intestine during digestion and, beyond the jokes that this subject usually generates, it is an absolutely normal physiological process. In some cases, however, abdominal gases can be a source of discomfort. This situation may now have a scientific explanation. A study by the Physiology and Pathophysiology of the Digestive Tract Group at Vall d’Hebron…

GMFH Editing Team
GMFH Editing Team

Gastric bypass surgery has been revealed as an effective method for fighting morbid obesity, as this kind of intervention usually leads to a significant weight loss. Until now, scientists were not aware of the important role of the gut microbiota in the positive effects of this treatment. According to a recent study published in Science Translational Medicine, the intervention could…

GMFH Editing Team
GMFH Editing Team

Gastric bypass surgery has been revealed as an effective method for fighting morbid obesity, as this kind of intervention usually leads to a significant weight loss. Until now, scientists were not aware of the important role of the gut microbiota in the positive effects of this treatment. According to a recent study published in Science Translational Medicine, the intervention could…

GMFH Editing Team
GMFH Editing Team

As it has been mentioned since the beginning of our blog, gut microbiota is increasingly raising more interest both from experts and society as a whole. Although some projects have been completed, there are others on the way. The good news right now comes from the United States, as the American Gastroenterological Association (AGA), co-organiser of the 2nd Gut Microbiota…

GMFH Editing Team
GMFH Editing Team

As it has been mentioned since the beginning of our blog, gut microbiota is increasingly raising more interest both from experts and society as a whole. Although some projects have been completed, there are others on the way. The good news right now comes from the United States, as the American Gastroenterological Association (AGA), co-organiser of the 2nd Gut Microbiota…

GMFH Editing Team
GMFH Editing Team

Research & Practice

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Celiac disease (CeD) is a complex immune mediated disorder that is triggered by abnormal immune responses to the dietary protein gluten, which is found in grains like wheat, barley, and rye. Normally, immune tolerance to dietary proteins prevents inflammatory immune responses from developing. However, in those with CeD, the presence of HLA susceptibility genes plus unknown environmental or immune triggers…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Celiac disease (CeD) is a complex immune mediated disorder that is triggered by abnormal immune responses to the dietary protein gluten, which is found in grains like wheat, barley, and rye. Normally, immune tolerance to dietary proteins prevents inflammatory immune responses from developing. However, in those with CeD, the presence of HLA susceptibility genes plus unknown environmental or immune triggers…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Mutualistic interactions between host and commensal microbiota have a pivotal role in colonization resistance (CR), protection against infections by enteric pathogens such as Salmonella spp. Previous research supporting this idea includes a study of the commensal bacterium Enterococcus faecium found in the mammals’ intestines that may improve host intestinal barrier function and limit the pathogenesis of infections caused by Salmonella…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Mutualistic interactions between host and commensal microbiota have a pivotal role in colonization resistance (CR), protection against infections by enteric pathogens such as Salmonella spp. Previous research supporting this idea includes a study of the commensal bacterium Enterococcus faecium found in the mammals’ intestines that may improve host intestinal barrier function and limit the pathogenesis of infections caused by Salmonella…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Gut microbiome in Crohn’s disease (CD) and ulcerative colitis (UC), the two main forms of inflammatory bowel disease (IBD), has been previously shown to have a reduced microbial diversity and may play a role in their aetiology and pathogenesis. However, until now no clear comparison between dysbiosis in CD and in UC has been investigated in a large cohort. A…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Gut microbiome in Crohn’s disease (CD) and ulcerative colitis (UC), the two main forms of inflammatory bowel disease (IBD), has been previously shown to have a reduced microbial diversity and may play a role in their aetiology and pathogenesis. However, until now no clear comparison between dysbiosis in CD and in UC has been investigated in a large cohort. A…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados