Digestive Health

News Watch

Stomach pain, flatulence, bloating, discomfort. These are just some of the symptoms of Irritable Bowel Syndrome (IBS), a chronic condition affecting more than 10% of the population with highest impact in women. Treatment cannot cure the condition, only alleviate the symptoms. Its origin is unknown, although increasingly more researchers suspect that imbalances in the gut microbiota may play a major…

GMFH Editing Team
GMFH Editing Team

Stomach pain, flatulence, bloating, discomfort. These are just some of the symptoms of Irritable Bowel Syndrome (IBS), a chronic condition affecting more than 10% of the population with highest impact in women. Treatment cannot cure the condition, only alleviate the symptoms. Its origin is unknown, although increasingly more researchers suspect that imbalances in the gut microbiota may play a major…

GMFH Editing Team
GMFH Editing Team

Thirty-three percent of people have a gene that predisposes them to celiac disease (CD), while only two to five percent of the population will receive a diagnosis of the condition. Elena Verdú, Associate Professor and researcher at McMaster University in Canada, wants to know why the unlucky minority end up with the disease. "We know that genes are necessary, but…

GMFH Editing Team
GMFH Editing Team

Thirty-three percent of people have a gene that predisposes them to celiac disease (CD), while only two to five percent of the population will receive a diagnosis of the condition. Elena Verdú, Associate Professor and researcher at McMaster University in Canada, wants to know why the unlucky minority end up with the disease. "We know that genes are necessary, but…

GMFH Editing Team
GMFH Editing Team

In inflammatory bowel disease (IBD), a set of conditions that includes Crohn’s disease and ulcerative colitis (UC), parts of the digestive tract become chronically inflamed. 'Debilitating' doesn't begin to describe IBD at its most intense: during a disease flare, someone who normally leads a busy and active life may have to put everything on hold to stay at home, close…

GMFH Editing Team
GMFH Editing Team

In inflammatory bowel disease (IBD), a set of conditions that includes Crohn’s disease and ulcerative colitis (UC), parts of the digestive tract become chronically inflamed. 'Debilitating' doesn't begin to describe IBD at its most intense: during a disease flare, someone who normally leads a busy and active life may have to put everything on hold to stay at home, close…

GMFH Editing Team
GMFH Editing Team

Butterflies in your stomach before a big presentation is a familiar experience, but surprisingly, scientists don't yet know exactly how this happens. The gut-brain axis – the brain's influence on the gastrointestinal tract and the other way around – is now a subject of keen scientific interest. A recent review, published in Neuropsychiatric Disease and Treatment, covered what we know…

GMFH Editing Team
GMFH Editing Team

Butterflies in your stomach before a big presentation is a familiar experience, but surprisingly, scientists don't yet know exactly how this happens. The gut-brain axis – the brain's influence on the gastrointestinal tract and the other way around – is now a subject of keen scientific interest. A recent review, published in Neuropsychiatric Disease and Treatment, covered what we know…

GMFH Editing Team
GMFH Editing Team

Digestion is extraordinarily complex, and there is a long list of ways it can go wrong. From constipation to bloating, digestive disorders can cause significant distress for infants and children as they develop. Fortunately, with emerging research on the microbiota, doctors, dietitians, and other healthcare professionals have a growing list of science-based strategies to use in addressing these problems. Healthcare…

GMFH Editing Team
GMFH Editing Team

Digestion is extraordinarily complex, and there is a long list of ways it can go wrong. From constipation to bloating, digestive disorders can cause significant distress for infants and children as they develop. Fortunately, with emerging research on the microbiota, doctors, dietitians, and other healthcare professionals have a growing list of science-based strategies to use in addressing these problems. Healthcare…

GMFH Editing Team
GMFH Editing Team

Research & Practice

Helicobacter pylori (Hp) chronic infection is increasing worldwide and is involved in the pathogenesis of chronic gastritis, peptic ulcers, and gastric cancer. Eradication of the bacterium through proton-pump inhibitor (PPI)-based triple therapy (PPI, amoxicillin and either clarithromycin or metronidazole and clarithromycin) or bismuth-based quadruple therapy (bismuth added to the standard twice-daily PPI-based triple therapy) has recently decreased, mainly due to…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Helicobacter pylori (Hp) chronic infection is increasing worldwide and is involved in the pathogenesis of chronic gastritis, peptic ulcers, and gastric cancer. Eradication of the bacterium through proton-pump inhibitor (PPI)-based triple therapy (PPI, amoxicillin and either clarithromycin or metronidazole and clarithromycin) or bismuth-based quadruple therapy (bismuth added to the standard twice-daily PPI-based triple therapy) has recently decreased, mainly due to…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Faecal microbiota transplantation (FMT) is currently investigated as a novel treatment option for several chronic diseases related to gut dysbiosis with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although clear reporting of FMT methodology is important to better understand and reproduce studies, reports of the methodological components of FMT interventions in clinical trials vary…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation (FMT) is currently investigated as a novel treatment option for several chronic diseases related to gut dysbiosis with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although clear reporting of FMT methodology is important to better understand and reproduce studies, reports of the methodological components of FMT interventions in clinical trials vary…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the gut microbiome could influence cancer outcomes through its interaction with host immunity. Indeed, mouse studies have shown the anti-cancer effects of chemotherapeutic drugs such as cyclophosphamide and celecoxib could be mediated by commensal species. However, the mechanisms by which gut microbial communities influence response to chemotherapeutic drugs remains poorly understood. Two recent studies using…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the gut microbiome could influence cancer outcomes through its interaction with host immunity. Indeed, mouse studies have shown the anti-cancer effects of chemotherapeutic drugs such as cyclophosphamide and celecoxib could be mediated by commensal species. However, the mechanisms by which gut microbial communities influence response to chemotherapeutic drugs remains poorly understood. Two recent studies using…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.