Category : Probiotics

It has been suggested that the first 3 years of life are a critical period for dietary interventions aimed at gut microbiota modulation for improving child growth and development—the so-called “window of opportunity for microbial modulation”. Contrary to current belief, recent research has found that the gut microbiome of young children (study; study) and adolescents (study) is different from that…

GMFH Editing Team
GMFH Editing Team

It has been suggested that the first 3 years of life are a critical period for dietary interventions aimed at gut microbiota modulation for improving child growth and development—the so-called “window of opportunity for microbial modulation”. Contrary to current belief, recent research has found that the gut microbiome of young children (study; study) and adolescents (study) is different from that…

GMFH Editing Team
GMFH Editing Team

The identification of an isolate at the strain level has been considered an essential requirement for any microbe that is intended to be commercialized as a probiotic. Strain-level identity is essential for both safety and efficacy evaluations. It enables traceability in laboratory tests, clinical trials and throughout the production and commercialization process. Although the health benefits of probiotics have been…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The identification of an isolate at the strain level has been considered an essential requirement for any microbe that is intended to be commercialized as a probiotic. Strain-level identity is essential for both safety and efficacy evaluations. It enables traceability in laboratory tests, clinical trials and throughout the production and commercialization process. Although the health benefits of probiotics have been…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

It is a well-known fact that caesarean section (c-section) birth is related to an increased risk of both immune and metabolic diseases later in life, possibly through aberrant gut microbiota composition and/or functional diversity. However, little is known about the effect of targeting gut microbiota with prebiotics and probiotics in c-section-born infants. A new randomized, double-blind, controlled multicentre study, led…

GMFH Editing Team
GMFH Editing Team

It is a well-known fact that caesarean section (c-section) birth is related to an increased risk of both immune and metabolic diseases later in life, possibly through aberrant gut microbiota composition and/or functional diversity. However, little is known about the effect of targeting gut microbiota with prebiotics and probiotics in c-section-born infants. A new randomized, double-blind, controlled multicentre study, led…

GMFH Editing Team
GMFH Editing Team

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team

Gut-related symptoms, including flatulence, bloating, heartburn, nausea, vomiting, constipation, diarrhoea, food intolerance, incontinence, and abdominal pain affect approximately one third of the general population, according to the World Gastroenterology Organisation. Among the functional gastrointestinal disorders (FGIDs) that are characterized by persistent and recurring GI symptoms, irritable bowel syndrome (IBS) affects around 11% of the population globally and can interfere with…

GMFH Editing Team
GMFH Editing Team

Gut-related symptoms, including flatulence, bloating, heartburn, nausea, vomiting, constipation, diarrhoea, food intolerance, incontinence, and abdominal pain affect approximately one third of the general population, according to the World Gastroenterology Organisation. Among the functional gastrointestinal disorders (FGIDs) that are characterized by persistent and recurring GI symptoms, irritable bowel syndrome (IBS) affects around 11% of the population globally and can interfere with…

GMFH Editing Team
GMFH Editing Team
Canadian Obesity Network

Although plenty of research in both animal models and humans during the last decade has explored the relationship between the gut microbiota and obesity and related metabolic disorders, the clinically relevant contribution of gut microbiota to obesity and related metabolic disorders is still unknown. The relationship between obesity and metabolic diseases has been recently covered in a review article by…

GMFH Editing Team
GMFH Editing Team

Canadian Obesity Network

Although plenty of research in both animal models and humans during the last decade has explored the relationship between the gut microbiota and obesity and related metabolic disorders, the clinically relevant contribution of gut microbiota to obesity and related metabolic disorders is still unknown. The relationship between obesity and metabolic diseases has been recently covered in a review article by…

GMFH Editing Team
GMFH Editing Team

Many questions arise when it comes to probiotics and gut microbiota. By what mechanisms of action can probiotics affect host health? What is the role of probiotics in preventing healthcare-associated infections? Do probiotics affect the intestinal barrier? The Gut Microbiota for Health publishing team has asked a selection of world-leading experts to weigh in on the answers, and we're pleased…

GMFH Editing Team
GMFH Editing Team

Many questions arise when it comes to probiotics and gut microbiota. By what mechanisms of action can probiotics affect host health? What is the role of probiotics in preventing healthcare-associated infections? Do probiotics affect the intestinal barrier? The Gut Microbiota for Health publishing team has asked a selection of world-leading experts to weigh in on the answers, and we're pleased…

GMFH Editing Team
GMFH Editing Team

At the end of 2017, GMFH celebrated its 5th anniversary. As a wrap-up of this celebration, we asked members of our Gut Microbiota for Health board of experts to share their thoughts, on video, about these 5 years in which they contributed toward increased knowledge about the gut microbiota and its role in health, and made the initiative what it’s…

GMFH Editing Team
GMFH Editing Team

At the end of 2017, GMFH celebrated its 5th anniversary. As a wrap-up of this celebration, we asked members of our Gut Microbiota for Health board of experts to share their thoughts, on video, about these 5 years in which they contributed toward increased knowledge about the gut microbiota and its role in health, and made the initiative what it’s…

GMFH Editing Team
GMFH Editing Team

Probiotics have a range of documented effects on human health, with hundreds of studies from the past several decades showing their ability to alter physical or behavioural phenotypes in humans. These human efficacy trials provide the necessary evidence to guide probiotic use. In designing a trial, however, the researchers often wonder how to select the best strain for the task…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Probiotics have a range of documented effects on human health, with hundreds of studies from the past several decades showing their ability to alter physical or behavioural phenotypes in humans. These human efficacy trials provide the necessary evidence to guide probiotic use. In designing a trial, however, the researchers often wonder how to select the best strain for the task…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.