Category : Fecal Microbiota Transplant

Faecal microbiota transplantation (FMT) has been previously reported as an effective treatment for recurrent Clostridium difficile infection (rCDI). Preclinical and clinical data have shown that restoration of donor-like beta diversity (i.e. species diversity compared to another individual) did not always correspond to direct restoration of an individual’s alpha diversity (i.e. the mean species diversity on a local scale), which suggests…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation (FMT) has been previously reported as an effective treatment for recurrent Clostridium difficile infection (rCDI). Preclinical and clinical data have shown that restoration of donor-like beta diversity (i.e. species diversity compared to another individual) did not always correspond to direct restoration of an individual’s alpha diversity (i.e. the mean species diversity on a local scale), which suggests…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The accumulation of excess abdominal fat is a crucial risk factor for cardio-metabolic disease and recent research has shown that gut microbiota may play an important role in obesity and metabolic disorders. However, little is known regarding the relationship between visceral fat and the human faecal microbiome. A recent cross-sectional study, led by Prof. Tim Spector and Dr. Jordana Bell…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The accumulation of excess abdominal fat is a crucial risk factor for cardio-metabolic disease and recent research has shown that gut microbiota may play an important role in obesity and metabolic disorders. However, little is known regarding the relationship between visceral fat and the human faecal microbiome. A recent cross-sectional study, led by Prof. Tim Spector and Dr. Jordana Bell…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Antibiotics, while highly effective at treating and preventing infections, may also increase the risk of susceptibility to infections, allergy, and metabolic syndrome and might even decrease efficacy outcomes of pharmacologic therapies by altering the composition and functions of the commensal microbiota.   In a perspective paper published in Science, Dr. Martin Blaser, from the New York University Langone Medical Centre…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Antibiotics, while highly effective at treating and preventing infections, may also increase the risk of susceptibility to infections, allergy, and metabolic syndrome and might even decrease efficacy outcomes of pharmacologic therapies by altering the composition and functions of the commensal microbiota.   In a perspective paper published in Science, Dr. Martin Blaser, from the New York University Langone Medical Centre…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation has been demonstrated to be a safe and highly effective therapeutic option for refractory C. difficile infection (CDI), and many studies have shown that it may possibly have applications in other illnesses such as inflammatory bowel disease (IBD) and in particular for ulcerative colitis (UC). According to a recent systematic review with meta-analysis including observational studies, during…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation has been demonstrated to be a safe and highly effective therapeutic option for refractory C. difficile infection (CDI), and many studies have shown that it may possibly have applications in other illnesses such as inflammatory bowel disease (IBD) and in particular for ulcerative colitis (UC). According to a recent systematic review with meta-analysis including observational studies, during…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Fecal microbiota transplantation (FMT) for patients with ulcerative colitis (UC) has shown mixed clinical results (see recent trials here and here). In a new pilot study, published as open access, Faming Zhang and colleagues tested the safety and efficacy of a "step-up" FMT strategy in 15 steroid-dependent UC patients. The step-up strategy was as follows: After all medications were discontinued,…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Fecal microbiota transplantation (FMT) for patients with ulcerative colitis (UC) has shown mixed clinical results (see recent trials here and here). In a new pilot study, published as open access, Faming Zhang and colleagues tested the safety and efficacy of a "step-up" FMT strategy in 15 steroid-dependent UC patients. The step-up strategy was as follows: After all medications were discontinued,…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

United European Gastroenterology (UEG) week starts today and runs until October 28th in Barcelona, Spain. UEG is a non-profit organization focused on advancing gastroenterology care, comprising 22,000 professional members from several European societies. With the event underway, GMFH brings you the ideas of two gastroenterologist-researchers about the impact of gut microbiota science on clinical practice. For clinicians, what are the…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

United European Gastroenterology (UEG) week starts today and runs until October 28th in Barcelona, Spain. UEG is a non-profit organization focused on advancing gastroenterology care, comprising 22,000 professional members from several European societies. With the event underway, GMFH brings you the ideas of two gastroenterologist-researchers about the impact of gut microbiota science on clinical practice. For clinicians, what are the…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Collection and sequencing of fecal material as a proxy of gut microbial content is becoming more and more frequent for clinical and/or research studies. However, there are still no universally accepted guidelines and it is consequently often difficult to choose appropriate methodologies for those who are not familiar with the field. This review evaluates the different options available for conducting…

Vincent Thomas
Vincent has a broad range of experience in microbial ecology, including environmental and clinical microbiology. He worked for 10 years at the interface between academics and private companies, succeeding in conducting strategic research projects and publishing more than 35 peer-reviewed papers.

Collection and sequencing of fecal material as a proxy of gut microbial content is becoming more and more frequent for clinical and/or research studies. However, there are still no universally accepted guidelines and it is consequently often difficult to choose appropriate methodologies for those who are not familiar with the field. This review evaluates the different options available for conducting…

Vincent Thomas
Vincent has a broad range of experience in microbial ecology, including environmental and clinical microbiology. He worked for 10 years at the interface between academics and private companies, succeeding in conducting strategic research projects and publishing more than 35 peer-reviewed papers.

In a recent issue of Annals of Internal Medicine, Cammarota et al. showed that the implementation of a fecal microbiota transplantation (FMT) program, available from June 2013 in the A. Gemelli University Hospital, an Italian academic tertiary care centre, led to fewer surgical procedures for severe C. difficile infection (CDI). Between January 2010 and April 2015, 901 patients with CDI…

GMFH Editing Team
GMFH Editing Team

In a recent issue of Annals of Internal Medicine, Cammarota et al. showed that the implementation of a fecal microbiota transplantation (FMT) program, available from June 2013 in the A. Gemelli University Hospital, an Italian academic tertiary care centre, led to fewer surgical procedures for severe C. difficile infection (CDI). Between January 2010 and April 2015, 901 patients with CDI…

GMFH Editing Team
GMFH Editing Team