Category : Gut Microbiota

Pediatric acute-onset neuropsychiatric syndrome (PANS) refers to a clinical spectrum of neuropsychiatric disorders triggered by environmental conditions, metabolic disorders and/or infections, which may increase children’s risk of sleep disturbances and mood disorders. A specific subset within the broader clinical spectrum of PANS includes pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections syndrome (PANDAS). An increasing amount of research is focusing…

GMFH Editing Team
GMFH Editing Team

Pediatric acute-onset neuropsychiatric syndrome (PANS) refers to a clinical spectrum of neuropsychiatric disorders triggered by environmental conditions, metabolic disorders and/or infections, which may increase children’s risk of sleep disturbances and mood disorders. A specific subset within the broader clinical spectrum of PANS includes pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections syndrome (PANDAS). An increasing amount of research is focusing…

GMFH Editing Team
GMFH Editing Team

Although intake of certain non-antibiotic drugs -antidiabetics such as metformin and acarbose, proton pump inhibitors, non-steroidal anti-inflammatory drugs, and second-generation antipsychotics, opioids and statins- that target human cells have been related to changes in the gut microbiome composition, little is known regarding the extent to which this happens for a broader range of drugs. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although intake of certain non-antibiotic drugs -antidiabetics such as metformin and acarbose, proton pump inhibitors, non-steroidal anti-inflammatory drugs, and second-generation antipsychotics, opioids and statins- that target human cells have been related to changes in the gut microbiome composition, little is known regarding the extent to which this happens for a broader range of drugs. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A carbohydrate-restricted diet has been emerging as an effective dietary intervention for non-alcoholic fatty liver disease (NAFLD) in humans. NAFLD is the most prevalent form of liver disease in western countries, affecting an estimated up to 30% of the population and has been reported to be an independent risk factor for increased mortality related to cardiovascular and liver diseases. However,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A carbohydrate-restricted diet has been emerging as an effective dietary intervention for non-alcoholic fatty liver disease (NAFLD) in humans. NAFLD is the most prevalent form of liver disease in western countries, affecting an estimated up to 30% of the population and has been reported to be an independent risk factor for increased mortality related to cardiovascular and liver diseases. However,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The prevalence of childhood allergic diseases is increasing throughout the world. Although previous research (here; here) has found that gut microbial colonization dynamics differ between allergic and healthy infants, little is known regarding the extent to which specific changes in gut microbiota composition in early life could be used as potential biomarkers of later allergic disease, or could be used…

GMFH Editing Team
GMFH Editing Team

The prevalence of childhood allergic diseases is increasing throughout the world. Although previous research (here; here) has found that gut microbial colonization dynamics differ between allergic and healthy infants, little is known regarding the extent to which specific changes in gut microbiota composition in early life could be used as potential biomarkers of later allergic disease, or could be used…

GMFH Editing Team
GMFH Editing Team

It is a well-known fact that caesarean section (c-section) birth is related to an increased risk of both immune and metabolic diseases later in life, possibly through aberrant gut microbiota composition and/or functional diversity. However, little is known about the effect of targeting gut microbiota with prebiotics and probiotics in c-section-born infants. A new randomized, double-blind, controlled multicentre study, led…

GMFH Editing Team
GMFH Editing Team

It is a well-known fact that caesarean section (c-section) birth is related to an increased risk of both immune and metabolic diseases later in life, possibly through aberrant gut microbiota composition and/or functional diversity. However, little is known about the effect of targeting gut microbiota with prebiotics and probiotics in c-section-born infants. A new randomized, double-blind, controlled multicentre study, led…

GMFH Editing Team
GMFH Editing Team

Although previous research has shown that host genetics (i.e., some human genes related to diet, metabolism, taste and immunity) are associated with the abundance of several gut bacterial taxa, the degree to which human genetics shape gut microbiome composition remains elusive. A new study, led by Prof. Eran Segal from the Department of Computer Science and Applied Mathematics and the…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although previous research has shown that host genetics (i.e., some human genes related to diet, metabolism, taste and immunity) are associated with the abundance of several gut bacterial taxa, the degree to which human genetics shape gut microbiome composition remains elusive. A new study, led by Prof. Eran Segal from the Department of Computer Science and Applied Mathematics and the…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although recent research in humans has found that the gut microbiota follows a circadian rhythm in vitro and responds to fluctuations in the hormone melatonin, further studies in humans related to the circadian rhythms in vivo are necessary and the exact mechanisms accounting for the observed bacterial rhythms have not been shown yet. Moreover, the impact of timing of food…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although recent research in humans has found that the gut microbiota follows a circadian rhythm in vitro and responds to fluctuations in the hormone melatonin, further studies in humans related to the circadian rhythms in vivo are necessary and the exact mechanisms accounting for the observed bacterial rhythms have not been shown yet. Moreover, the impact of timing of food…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Functional dyspepsia (FD) -defined as discomfort or pain in the upper abdomen, often related to food intake, but with no apparent organic cause- is one of the most prevalent functional gastrointestinal disorders. Increasing evidence has emerged of the involvement of the gut microbiota as a target for managing functional gastrointestinal disorders. However, the therapeutic benefits and future perspectives of the…

GMFH Editing Team
GMFH Editing Team

Functional dyspepsia (FD) -defined as discomfort or pain in the upper abdomen, often related to food intake, but with no apparent organic cause- is one of the most prevalent functional gastrointestinal disorders. Increasing evidence has emerged of the involvement of the gut microbiota as a target for managing functional gastrointestinal disorders. However, the therapeutic benefits and future perspectives of the…

GMFH Editing Team
GMFH Editing Team

Preeclampsia and preterm birth are major risks in pregnancy that are characterized by an increased inflammatory response, which is partly explained by microbial stimulation of the innate immune system and generation of pro-inflammatory mediators. Although the use of probiotics might reduce certain complications of pregnancy (here; here), little is known regarding whether timing of probiotic exposure could affect the pathophysiology…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Preeclampsia and preterm birth are major risks in pregnancy that are characterized by an increased inflammatory response, which is partly explained by microbial stimulation of the innate immune system and generation of pro-inflammatory mediators. Although the use of probiotics might reduce certain complications of pregnancy (here; here), little is known regarding whether timing of probiotic exposure could affect the pathophysiology…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados