Category : Parkinson

Recent research has shown the presence of gut dysbiosis related to a shift in short-chain fatty acids in patients with Parkinson’s disease (PD). Besides this, constipation is a major nonmotor feature of PD and little is known about whether probiotics and prebiotics could improve constipation in patients with PD. A recent randomized, double-blind, placebo-controlled trial, led by Dr. Emanuele Cereda…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Recent research has shown the presence of gut dysbiosis related to a shift in short-chain fatty acids in patients with Parkinson’s disease (PD). Besides this, constipation is a major nonmotor feature of PD and little is known about whether probiotics and prebiotics could improve constipation in patients with PD. A recent randomized, double-blind, placebo-controlled trial, led by Dr. Emanuele Cereda…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Recent research has given important insights into the role of gut microbiota alterations in Parkinson’s disease (PD). Although motor deficits (including tremor, bradykinesia and rigidity) are the cardinal symptoms of PD, non-motor symptoms (NMS) (constipation, gastrointestinal disturbances, sleep disturbances and sensory alterations, among others) are also apparent and affect PD patients’ quality of life more negatively than the motor symptoms.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Recent research has given important insights into the role of gut microbiota alterations in Parkinson’s disease (PD). Although motor deficits (including tremor, bradykinesia and rigidity) are the cardinal symptoms of PD, non-motor symptoms (NMS) (constipation, gastrointestinal disturbances, sleep disturbances and sensory alterations, among others) are also apparent and affect PD patients’ quality of life more negatively than the motor symptoms.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

From cradle to grave, our gut is our most important physiological connection to the microbiome.  While significant progress has been made to understand the development of this complex community early in life, it is only recently that researchers have begun to understand its deterioration later in life.  Scientists are now recognizing the important influence the microbiome may have on the…

GMFH Editing Team
GMFH Editing Team

From cradle to grave, our gut is our most important physiological connection to the microbiome.  While significant progress has been made to understand the development of this complex community early in life, it is only recently that researchers have begun to understand its deterioration later in life.  Scientists are now recognizing the important influence the microbiome may have on the…

GMFH Editing Team
GMFH Editing Team

The pathomechanism of Parkinson´s disease (PD) is well known but its origin is far from completely understood. The fact that among the prodromal signs of PD are constipation and a number of other (autonomically regulated) symptoms that occur years before the onset of movement disorders has given rise to the idea that a peripheral origin may exist. Since a-synuclein inclusions…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The pathomechanism of Parkinson´s disease (PD) is well known but its origin is far from completely understood. The fact that among the prodromal signs of PD are constipation and a number of other (autonomically regulated) symptoms that occur years before the onset of movement disorders has given rise to the idea that a peripheral origin may exist. Since a-synuclein inclusions…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

I participated in the "Targeting microbiota" congress at Pasteur Institute because I considered the topics discussed very interesting and relevant to my research. For me microbiome conferences are still a rather foreign territory, but I very much like to talk to people with a very different view from what I have. And my learning curve in the microbiome field is…

Filip Scheperjans
I am German and studied medicine at the Heinrich-Heine-University in Duesseldorf, Germany and was a visiting student at the National Hospital for Neurology and Neurosurgery in London and at the Mount Sinai Medical School in New York. During my studies I started work on my doctoral theses in the C & U Vogt Brain Research Institute about the microscopical and neurochemical anatomy of the human parietal lobe. After graduating, I continued work on my thesis at the Institute of Medicine at the Research Center in Juelich. I received my doctoral degree and my thesis was awarded the best medical thesis in 2008 at Duesseldorf University. In 2007 I moved to Finland and started my clinical specialization in neurology. During this period I completed a 6 month fellowship in our clinical stroke research lab which gave me experience in the planning and conduction of clinical trials. I received my specialist degree in 2013.

I participated in the "Targeting microbiota" congress at Pasteur Institute because I considered the topics discussed very interesting and relevant to my research. For me microbiome conferences are still a rather foreign territory, but I very much like to talk to people with a very different view from what I have. And my learning curve in the microbiome field is…

Filip Scheperjans
I am German and studied medicine at the Heinrich-Heine-University in Duesseldorf, Germany and was a visiting student at the National Hospital for Neurology and Neurosurgery in London and at the Mount Sinai Medical School in New York. During my studies I started work on my doctoral theses in the C & U Vogt Brain Research Institute about the microscopical and neurochemical anatomy of the human parietal lobe. After graduating, I continued work on my thesis at the Institute of Medicine at the Research Center in Juelich. I received my doctoral degree and my thesis was awarded the best medical thesis in 2008 at Duesseldorf University. In 2007 I moved to Finland and started my clinical specialization in neurology. During this period I completed a 6 month fellowship in our clinical stroke research lab which gave me experience in the planning and conduction of clinical trials. I received my specialist degree in 2013.