Recent advances in research have described the importance of gut microbiota in influencing interactions between the central and the enteric nervous systems. These brain-gut interactions appear to be bidirectional by means of neural, endocrine, immune, and humoral signals. Most of the data have been acquired using rodents (mice or rats) and pigs.

This Chinese study aimed to characterize the gut microbiota of patients with major depressive disorder (MDD): one group of patients with acute MDD (who scored high on a depression scale, indicating clinically significant depression), called 'active-MDD', and a second group of patients with a history of MDD who had responded to treatment (achieving a 50% reduction in depression scale scores after 4 weeks of treatment), called 'responded-MDD'.

The Gut-Brain Axis: A Two-Way Street

25 Aug 2015

by Paul Enck

A study by De Palma, et al. used germ-free and specific pathogen-free mouse models to investigate the effects of early-life stress.

Does fermented food consumption lower social anxiety?

22 Jul 2015

by Mary Ellen Sanders

Fermented foods are not included in the recently revised ISAPP definition of probiotics, since the bacteria they contain are uncharacterized. But scientists are nevertheless studying how these foods may affect health, including brain function.

Philippe de Timary, MD., Ph.D., is a researcher and psychiatrist in the department of Adult Psychiatry and Institute of Neuroscience at Catholic University of Louvain and Hospital Saint-Luc in Brussels, Belgium. With a colleague, Professor Peter Starkel, he opened a clinical unit in the hospital

Functional GI disorders: From children to adults

23 Oct 2012

by GMFH Editing Team

Speakers: Nicholas Talley (Australia), Annamaria Staiano (Italy), Marc Benninga (The Netherlands), Lukas van Oudenhove (Belgium)   “The definition of functional gastrointestinal disorders (FGIDs) as laid out in the Rome III criteria is now highly questionable.” This was the view expressed

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