This clinically-oriented summary of gut microbiota research was developed by members of the Gut Microbiota and Health section of the European Society of Neurogastroenterology & Motility (ESNM), and was approved by the Board of Directors of the Section and by the Steering Committee of ESNM.

The observed success of the low-FODMAP diet in reducing gastrointestinal (GI) symptoms in IBS made a group of researchers ask whether the diet could also address functional GI symptoms in those with inflammatory bowel diseases (IBDs) such as Crohn's disease. This idea was explored in a recent study from the group at Monash University (Australia) that originally developed and tested the low-FODMAP diet.

A recent study, led by Dr. Wendy A. Henderson from the National Institute of Nursing Research at National Institutes of Health (NIH) in Bethesda (USA), and co-authored by Research Fellow Dr. Nicolaas Fourie, has found that the oral microbiota could be a useful source of information in patients with irritable bowel syndrome (IBS).

Inflammatory bowel disease (IBD) is a family of intestinal disorders including Crohn’s disease (CD) and ulcerative colitis (UC) that are characterized by chronic and recurring periods of severe colonic (UC) or intestinal (CD) inflammation and extraintestinal symptoms.

Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, affecting more than 10% of the population, with the highest impact in women. Although its origin is still unknown, reduced gut microbial diversity could be involved in its development.

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