Category : IBD

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Gut microbiome in Crohn’s disease (CD) and ulcerative colitis (UC), the two main forms of inflammatory bowel disease (IBD), has been previously shown to have a reduced microbial diversity and may play a role in their aetiology and pathogenesis. However, until now no clear comparison between dysbiosis in CD and in UC has been investigated in a large cohort. A…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Gut microbiome in Crohn’s disease (CD) and ulcerative colitis (UC), the two main forms of inflammatory bowel disease (IBD), has been previously shown to have a reduced microbial diversity and may play a role in their aetiology and pathogenesis. However, until now no clear comparison between dysbiosis in CD and in UC has been investigated in a large cohort. A…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the gut microbiota may have a role in the pathogenesis of immune-related diseases involving chronic inflammation, such as rheumatoid arthritis, Crohn’s disease, multiple sclerosis, and others. A recent review, led by Dr. Hai Lu from the Department of Orthopedic Surgery at The Third Affiliated Hospital of Southern Medical University in Guangzhou (China), discusses the existing…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the gut microbiota may have a role in the pathogenesis of immune-related diseases involving chronic inflammation, such as rheumatoid arthritis, Crohn’s disease, multiple sclerosis, and others. A recent review, led by Dr. Hai Lu from the Department of Orthopedic Surgery at The Third Affiliated Hospital of Southern Medical University in Guangzhou (China), discusses the existing…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Dietary fibre from plant-based foods is the most common fuel for some bacterial species in the gut microbiota and in some contexts has been shown to play a key role in protecting the host against immune-mediated diseases such food allergies and even neurological disorders. A diet rich in microbiota-accessible carbohydrates (MACs), which are complex carbohydrates found in fruits, vegetables, whole…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Dietary fibre from plant-based foods is the most common fuel for some bacterial species in the gut microbiota and in some contexts has been shown to play a key role in protecting the host against immune-mediated diseases such food allergies and even neurological disorders. A diet rich in microbiota-accessible carbohydrates (MACs), which are complex carbohydrates found in fruits, vegetables, whole…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Crohn’s disease (CD) is a relapsing inflammatory bowel disease that results from a complex interplay between host genetic factors and endogenous microbial communities. Host factors and environmental factors may have effects on the microbiota and possibly initiate inflammation, but then gut dysbiosis may play a role in maintaining this cycle of inflammation. While the vast majority of studies have focused…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Crohn’s disease (CD) is a relapsing inflammatory bowel disease that results from a complex interplay between host genetic factors and endogenous microbial communities. Host factors and environmental factors may have effects on the microbiota and possibly initiate inflammation, but then gut dysbiosis may play a role in maintaining this cycle of inflammation. While the vast majority of studies have focused…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Crohn’s disease (CD) is a chronic inflammatory condition of diverse aetiology in which host genetics and the gut microbiome may interact to regulate susceptibility. People with CD tend to have higher numbers of a type of gut bacteria known as adherent-invasive Escherichia coli (AIEC) in their guts. Besides this, acute infectious gastroenteritis caused by Salmonella or other enteric pathogens, increase…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Crohn’s disease (CD) is a chronic inflammatory condition of diverse aetiology in which host genetics and the gut microbiome may interact to regulate susceptibility. People with CD tend to have higher numbers of a type of gut bacteria known as adherent-invasive Escherichia coli (AIEC) in their guts. Besides this, acute infectious gastroenteritis caused by Salmonella or other enteric pathogens, increase…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The intestinal microbiota appears to be a key determinant of health and disease. Indeed, microbiota differences are associated with a number of inflammatory diseases, including inflammatory bowel disease (IBD). However, the method by which alterations in the microbiota composition (influenced by genetics, the environment, and diet) contribute to IBD pathogenesis is not well understood. In a recently published paper in…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

The intestinal microbiota appears to be a key determinant of health and disease. Indeed, microbiota differences are associated with a number of inflammatory diseases, including inflammatory bowel disease (IBD). However, the method by which alterations in the microbiota composition (influenced by genetics, the environment, and diet) contribute to IBD pathogenesis is not well understood. In a recently published paper in…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

A diet low in FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) has been studied mostly in the context of irritable bowel syndrome (IBS) and is known to reduce functional gastrointestinal symptoms in this population. In addition, altering FODMAP intake appears to impact fecal microbiota composition in both healthy individuals and those with IBS. The observed success of the low-FODMAP diet…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

A diet low in FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) has been studied mostly in the context of irritable bowel syndrome (IBS) and is known to reduce functional gastrointestinal symptoms in this population. In addition, altering FODMAP intake appears to impact fecal microbiota composition in both healthy individuals and those with IBS. The observed success of the low-FODMAP diet…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Inflammatory bowel disease (IBD) is a family of intestinal disorders including Crohn’s disease (CD) and ulcerative colitis (UC) that are characterized by chronic and recurring periods of severe colonic (UC) or intestinal (CD) inflammation and extraintestinal symptoms. While the pathogenesis is unknown and seen as controversial, among others a dysregulated immune response in genetically susceptible individuals is discussed. It has…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Inflammatory bowel disease (IBD) is a family of intestinal disorders including Crohn’s disease (CD) and ulcerative colitis (UC) that are characterized by chronic and recurring periods of severe colonic (UC) or intestinal (CD) inflammation and extraintestinal symptoms. While the pathogenesis is unknown and seen as controversial, among others a dysregulated immune response in genetically susceptible individuals is discussed. It has…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

A new report, led by Dr. Ken Cadwell from the New York University School of Medicine in New York (USA), has found that a symbiotic relationship between intestinal helminths and host may play a role in inhibiting intestinal inflammatory responses.   Changes in the gut microbiota and decreased exposure to intestinal helminths have been suggested as factors in the increased…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

A new report, led by Dr. Ken Cadwell from the New York University School of Medicine in New York (USA), has found that a symbiotic relationship between intestinal helminths and host may play a role in inhibiting intestinal inflammatory responses.   Changes in the gut microbiota and decreased exposure to intestinal helminths have been suggested as factors in the increased…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados