Category : Functional Disorders

Metabolites produced by the gut microbiota may affect host physiology both directly and indirectly. Tryptophan is an essential amino acid and a precursor to several such metabolites. Tryptamine is important example of a bacterially-produced, tryptophan-derived metabolite with previously unknown functions in the gastrointestinal tract. A new study, published in Cell Host & Microbe and led by Dr. Purna C. Kashyap…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

Metabolites produced by the gut microbiota may affect host physiology both directly and indirectly. Tryptophan is an essential amino acid and a precursor to several such metabolites. Tryptamine is important example of a bacterially-produced, tryptophan-derived metabolite with previously unknown functions in the gastrointestinal tract. A new study, published in Cell Host & Microbe and led by Dr. Purna C. Kashyap…

Megan Mouw
Megan Mouw holds a Bachelor of Science in microbiology from McGill University (Canada). Driven by her experiences at UCSF medical center in San Francisco, Megan is passionate about the role that the gut microbiota plays in maintaining health and wellness. She is currently perusing graduate studies in Microbiology and Environmental Toxicology at the University of California Santa Cruz and hopes to share her love of science through writing.

Functional dyspepsia (FD) -defined as discomfort or pain in the upper abdomen, often related to food intake, but with no apparent organic cause- is one of the most prevalent functional gastrointestinal disorders. Increasing evidence has emerged of the involvement of the gut microbiota as a target for managing functional gastrointestinal disorders. However, the therapeutic benefits and future perspectives of the…

GMFH Editing Team
GMFH Editing Team

Functional dyspepsia (FD) -defined as discomfort or pain in the upper abdomen, often related to food intake, but with no apparent organic cause- is one of the most prevalent functional gastrointestinal disorders. Increasing evidence has emerged of the involvement of the gut microbiota as a target for managing functional gastrointestinal disorders. However, the therapeutic benefits and future perspectives of the…

GMFH Editing Team
GMFH Editing Team

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team

Gut-related symptoms, including flatulence, bloating, heartburn, nausea, vomiting, constipation, diarrhoea, food intolerance, incontinence, and abdominal pain affect approximately one third of the general population, according to the World Gastroenterology Organisation. Among the functional gastrointestinal disorders (FGIDs) that are characterized by persistent and recurring GI symptoms, irritable bowel syndrome (IBS) affects around 11% of the population globally and can interfere with…

GMFH Editing Team
GMFH Editing Team

Gut-related symptoms, including flatulence, bloating, heartburn, nausea, vomiting, constipation, diarrhoea, food intolerance, incontinence, and abdominal pain affect approximately one third of the general population, according to the World Gastroenterology Organisation. Among the functional gastrointestinal disorders (FGIDs) that are characterized by persistent and recurring GI symptoms, irritable bowel syndrome (IBS) affects around 11% of the population globally and can interfere with…

GMFH Editing Team
GMFH Editing Team

Although probiotics have been reported to improve symptoms of irritable bowel syndrome (IBS), data in humans regarding their effects on psychiatric comorbidities is scarce. A new study, led by Prof. Premysl Bercik from the Department of Medicine at the Farncombe Family Digestive Health Research Institute at the McMaster University in Hamilton (Canada), has found that the probiotic Bifidobacterium longum NCC3001…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although probiotics have been reported to improve symptoms of irritable bowel syndrome (IBS), data in humans regarding their effects on psychiatric comorbidities is scarce. A new study, led by Prof. Premysl Bercik from the Department of Medicine at the Farncombe Family Digestive Health Research Institute at the McMaster University in Hamilton (Canada), has found that the probiotic Bifidobacterium longum NCC3001…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Constipation is a common condition that may result from altered gastrointestinal motility. Several factors appear relevant to gut motility: the gut luminal environment (including the gastrointestinal microbiota and fermentation), as well as factors related to the immune system, the enteric nervous system, and the central nervous system. Previous research has found associations between colonic transit time and aspects of patients’…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Constipation is a common condition that may result from altered gastrointestinal motility. Several factors appear relevant to gut motility: the gut luminal environment (including the gastrointestinal microbiota and fermentation), as well as factors related to the immune system, the enteric nervous system, and the central nervous system. Previous research has found associations between colonic transit time and aspects of patients’…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

For those seeking the latest science on gut health and its applications to clinical practice, Paris was the place to be on March 11th and 12th, 2017. At the 6th GMFH World Summit, over 400 professionals from all over the world met to review the past decade of advances in gut microbiota science and where the field is headed in…

GMFH Editing Team
GMFH Editing Team

For those seeking the latest science on gut health and its applications to clinical practice, Paris was the place to be on March 11th and 12th, 2017. At the 6th GMFH World Summit, over 400 professionals from all over the world met to review the past decade of advances in gut microbiota science and where the field is headed in…

GMFH Editing Team
GMFH Editing Team

Public awareness about the importance of the gut microbiota is growing, but many nutrition professionals struggle to know how to incorporate findings from gut microbiota science into their practice. In a rapidly-progressing field, what should clinicians know about how gut microbes and diet interact to produce different health outcomes? At the 2017 Gut Microbiota for Health World Summit in Paris…

GMFH Editing Team
GMFH Editing Team

Public awareness about the importance of the gut microbiota is growing, but many nutrition professionals struggle to know how to incorporate findings from gut microbiota science into their practice. In a rapidly-progressing field, what should clinicians know about how gut microbes and diet interact to produce different health outcomes? At the 2017 Gut Microbiota for Health World Summit in Paris…

GMFH Editing Team
GMFH Editing Team

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados