Category : Digestive Health

Although probiotics have been reported to improve symptoms of irritable bowel syndrome (IBS), data in humans regarding their effects on psychiatric comorbidities is scarce. A new study, led by Prof. Premysl Bercik from the Department of Medicine at the Farncombe Family Digestive Health Research Institute at the McMaster University in Hamilton (Canada), has found that the probiotic Bifidobacterium longum NCC3001…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although probiotics have been reported to improve symptoms of irritable bowel syndrome (IBS), data in humans regarding their effects on psychiatric comorbidities is scarce. A new study, led by Prof. Premysl Bercik from the Department of Medicine at the Farncombe Family Digestive Health Research Institute at the McMaster University in Hamilton (Canada), has found that the probiotic Bifidobacterium longum NCC3001…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Constipation is a common condition that may result from altered gastrointestinal motility. Several factors appear relevant to gut motility: the gut luminal environment (including the gastrointestinal microbiota and fermentation), as well as factors related to the immune system, the enteric nervous system, and the central nervous system. Previous research has found associations between colonic transit time and aspects of patients’…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Constipation is a common condition that may result from altered gastrointestinal motility. Several factors appear relevant to gut motility: the gut luminal environment (including the gastrointestinal microbiota and fermentation), as well as factors related to the immune system, the enteric nervous system, and the central nervous system. Previous research has found associations between colonic transit time and aspects of patients’…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

For those seeking the latest science on gut health and its applications to clinical practice, Paris was the place to be on March 11th and 12th, 2017. At the 6th GMFH World Summit, over 400 professionals from all over the world met to review the past decade of advances in gut microbiota science and where the field is headed in…

GMFH Editing Team
GMFH Editing Team

For those seeking the latest science on gut health and its applications to clinical practice, Paris was the place to be on March 11th and 12th, 2017. At the 6th GMFH World Summit, over 400 professionals from all over the world met to review the past decade of advances in gut microbiota science and where the field is headed in…

GMFH Editing Team
GMFH Editing Team

Public awareness about the importance of the gut microbiota is growing, but many nutrition professionals struggle to know how to incorporate findings from gut microbiota science into their practice. In a rapidly-progressing field, what should clinicians know about how gut microbes and diet interact to produce different health outcomes? At the 2017 Gut Microbiota for Health World Summit in Paris…

GMFH Editing Team
GMFH Editing Team

Public awareness about the importance of the gut microbiota is growing, but many nutrition professionals struggle to know how to incorporate findings from gut microbiota science into their practice. In a rapidly-progressing field, what should clinicians know about how gut microbes and diet interact to produce different health outcomes? At the 2017 Gut Microbiota for Health World Summit in Paris…

GMFH Editing Team
GMFH Editing Team

Helicobacter pylori (Hp) chronic infection is increasing worldwide and is involved in the pathogenesis of chronic gastritis, peptic ulcers, and gastric cancer. Eradication of the bacterium through proton-pump inhibitor (PPI)-based triple therapy (PPI, amoxicillin and either clarithromycin or metronidazole and clarithromycin) or bismuth-based quadruple therapy (bismuth added to the standard twice-daily PPI-based triple therapy) has recently decreased, mainly due to…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Helicobacter pylori (Hp) chronic infection is increasing worldwide and is involved in the pathogenesis of chronic gastritis, peptic ulcers, and gastric cancer. Eradication of the bacterium through proton-pump inhibitor (PPI)-based triple therapy (PPI, amoxicillin and either clarithromycin or metronidazole and clarithromycin) or bismuth-based quadruple therapy (bismuth added to the standard twice-daily PPI-based triple therapy) has recently decreased, mainly due to…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Faecal microbiota transplantation (FMT) is currently investigated as a novel treatment option for several chronic diseases related to gut dysbiosis with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although clear reporting of FMT methodology is important to better understand and reproduce studies, reports of the methodological components of FMT interventions in clinical trials vary…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation (FMT) is currently investigated as a novel treatment option for several chronic diseases related to gut dysbiosis with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although clear reporting of FMT methodology is important to better understand and reproduce studies, reports of the methodological components of FMT interventions in clinical trials vary…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the gut microbiome could influence cancer outcomes through its interaction with host immunity. Indeed, mouse studies have shown the anti-cancer effects of chemotherapeutic drugs such as cyclophosphamide and celecoxib could be mediated by commensal species. However, the mechanisms by which gut microbial communities influence response to chemotherapeutic drugs remains poorly understood. Two recent studies using…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the gut microbiome could influence cancer outcomes through its interaction with host immunity. Indeed, mouse studies have shown the anti-cancer effects of chemotherapeutic drugs such as cyclophosphamide and celecoxib could be mediated by commensal species. However, the mechanisms by which gut microbial communities influence response to chemotherapeutic drugs remains poorly understood. Two recent studies using…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous preclinical and clinical data have reported that alterations in the bidirectional interactions of the central nervous system with the gut (called the gut-brain axis) may be involved in irritable bowel syndrome (IBS) pathophysiology. Interestingly, IBS symptom severity has also been related to faecal microbiota signature. However, it is still uncertain to what extent gut microbial composition can be used…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Faecal microbiota transplantation (FMT) is a therapy targeting the gut microbiome with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although gut microbiota dysbiosis is involved in the pathogenesis of ulcerative colitis, the role of FMT as a therapy for it is still controversial as the two big randomised controlled trials done previously (here; here)…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Celiac disease (CeD) is a complex immune mediated disorder that is triggered by abnormal immune responses to the dietary protein gluten, which is found in grains like wheat, barley, and rye. Normally, immune tolerance to dietary proteins prevents inflammatory immune responses from developing. However, in those with CeD, the presence of HLA susceptibility genes plus unknown environmental or immune triggers…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Celiac disease (CeD) is a complex immune mediated disorder that is triggered by abnormal immune responses to the dietary protein gluten, which is found in grains like wheat, barley, and rye. Normally, immune tolerance to dietary proteins prevents inflammatory immune responses from developing. However, in those with CeD, the presence of HLA susceptibility genes plus unknown environmental or immune triggers…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.